showing 7 related works from this author
Optimization of electrospun polylactide-based ultrathin fibers for osteoconductive bone scaffolds
2011
Bone tissue interfacial scaffolds, which encourage cell growth, are critical determinants for clinical success after implant surgery. Over the years, a number of resorbable configurations have emerged for bone cell support and growth, but only a few have demonstrated clinical efficacy. Polymer coatings produced by electrospinning are regarded as very promising bone interfaces because of the ultrathin-scaled dimensions of its physical structure. In this study, the morphology, composition, thermal properties, and cell growth viability of a number of polylactide-based systems containing different binary and ternary formulations of this biomaterial with collagen and commercial hydroxyapatite na…
Effect of graphene nanoplatelets on the dielectric permittivity and segmental motions of electrospun poly(ethylene-co-vinyl alcohol) nanofibers
2021
The influence of the addition of graphene nanoplatelets (GNPs) on the intra/inter – molecular segmental motions of poly(ethylene-co-vinyl alcohol) (EVOH) was assessed by means of dielectric thermal analysis (DETA). The relaxation spectra were studied in terms of the dielectric permittivity (ε′) and the dielectric loss tangent (tan δ) at wide ranges of frequency (from 10−2 to 107 Hz) and temperature (from -150 to 140 °C). Two relaxation zones were disthinguished. Below the glass transition temperature (Tg), two β-relaxations were observed, which are characteristic local modes of mobility of the EVOH side groups, and related to the influence of the different surroundings of ethylene or vinyl …
Stabilization of a nutraceutical omega-3 fatty acid by encapsulation in ultrathin electrosprayed zein prolamine.
2010
Docosahexaenoic acid (DHA) is a long chain polyunsaturated fatty acid of the omega-3 series (omega-3), which exerts strong positive influences on human health. The target of this study was the stabilization by encapsulation of this bioactive ingredient in zein ultrathin capsules produced by electrospraying. The zein ultrathin DHA encapsulation was observed by ATR-FTIR spectroscopy to be more efficient against degradation under both ambient conditions and in a confined space (so-called headspace experiment). In the latter case, that more closely simulates a sealed food packaging situation, the bioactive DHA was considerably more stable. By fitting the degradation data to a specific auto-deco…
Novel antimicrobial ultrathin structures of zein/chitosan blends obtained by electrospinning
2009
Abstract This paper describes the formulation, morphology and biocide properties of novel antimicrobial electrospun zein based ultrathin fiber structures. From the results, it was found that the electrospun fibers of zein can turn the material into a new strong antimicrobial ultrathin-structured system due to retention of remnant amounts of trifluoroacetic acid as determined by ATR–FTIR spectroscopy. Unfortunately, this system may be considered to yield very aggressive high acidic media due to release of the strong acid, which causes the antimicrobial behavior. Nevertheless, since biocide properties are more desirable at mild acidic conditions, blending zein with the natural antimicrobial c…
Electrospun Poly(ethylene-co-vinyl alcohol)/Graphene Nanoplatelets Composites of Interest in Intelligent Food Packaging Applications
2018
Graphene nanoplatelets (GNPs) were synthetized from graphite powder and, thereafter, embedded in poly(ethylene-co-vinyl alcohol) (EVOH) fibers by electrospinning in the 0.1&ndash
Controlled Delivery of Gentamicin Antibiotic from Bioactive Electrospun Polylactide-Based Ultrathin Fibers
2011
The purpose of this study was to generate ultrathin fibers based on polylactide (PLA) biopolyester with antimicrobial controlled release capacity to treat bacterial infections. To achieve this objective, gentamicin antibiotic was encapsulated into pure PLA fibers, a blend of PLA–collagen and coaxial fibers containing a skin of PLA and a core of collagen using the electrospinning technique. The morphology of the gentamicin-loaded fibers and the antibiotic distribution within the fibers were examined by SEM and TEM. The drug delivery profile of the different electrospun fibers was analyzed using a spectrophotometric method. The performance for treating common possible post-surgical infections…
Comparative performance of electrospun collagen nanofibers cross-linked by means of different methods.
2009
[EN] Collagen, as the major structural protein of the extracellular matrix in animals, is a versatile biomaterial of great interest in various engineering applications. Electrospun nanofibers of collagen are regarded as very promising materials for tissue engineering applications because they can reproduce the morphology of the natural bone but have as a drawback a poor structural consistency in wet conditions. In this paper, a comparative study between the performance of different cross-linking methods such as a milder enzymatic treatment procedure using transglutaminase, the use of N-[3-(dimethylamino)propyl]-N¿-ethylcarbodiimide hydrochloride/ N-hydroxysuccinimide, and genipin, and the u…