0000000000084601
AUTHOR
Emanuele Lentini
Coronary endarterectomy to facilitate bypass surgery for patients with extensive stenting of the left anterior descending artery
A 52-year-old male. Admitted for acute coronary syndrome because of three-vessel disease with a FMJ–LAD
Ascending aorta phenotypic and genotypic changes in bicuspid aortic valve disease
Bicuspid aortic valve (BAV) with left-right (L-R), right-non coronary (R-NC) and left-non coronary (L-NC) cusp fusion represents distinct pathological entities and the rate of aortic enlargement varies according to the pattern of cusps fusion (1). Here, we investigated the histological features of aneurysms associated to different BAV phenotypes and we looked for specific microRNAs (miRNA) as biomarkers of medial degeneration severity. Aortic specimens and blood were obtained from BAV patients treated surgically for the repair of thoracic aortic aneurysm and were divided into two groups: low grade medial degeneration (LGMD, n=10); high grade medial degeneration (HGMD, n=10). A control group…