0000000000085282

AUTHOR

I. N. Ferrier

showing 2 related works from this author

Neuropsychological testing of cognitive impairment in euthymic bipolar disorder: an individual patient data meta-analysis

2013

© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

AdultMalemedicine.medical_specialtyBipolar DisorderBipolar disorderTrail Making TestReviewNeuropsychological TestsVerbal learning03 medical and health sciencesMental Processes0302 clinical medicineRisk FactorsmedicineMemory spanHumansMental CompetencyAffective SymptomsBipolar disorderAge of OnsetPsychiatryPsychiatric Status Rating ScalesPsychotropic DrugsNeuropsychologyConfounding Factors EpidemiologicMiddle Agedmedicine.disease030227 psychiatryAffectPsychiatry and Mental healthMoodCognitive impairmentSchizophreniaNeuropsychological testsFemaleVerbal memoryCognition DisordersPsychology030217 neurology & neurosurgeryClinical psychology
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Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

2019

Crohn Disease (CD) is a complex genetic disorder for which more than 140 genes have been identified using genome wide association studies (GWAS). However, the genetic architecture of the trait remains largely unknown. The recent development of machine learning (ML) approaches incited us to apply them to classify healthy and diseased people according to their genomic information. The Immunochip dataset containing 18,227 CD patients and 34,050 healthy controls enrolled and genotyped by the international Inflammatory Bowel Disease genetic consortium (IIBDGC) has been re-analyzed using a set of ML methods: penalized logistic regression (LR), gradient boosted trees (GBT) and artificial neural ne…

Male/692/4020/1503/257/1402GenotypeGenotyping TechniquesLOCI/45/43lcsh:MedicinePolymorphism Single NucleotideCrohn's disease genetics genome wide associationArticleDeep LearningCrohn DiseaseINDEL MutationGenetics researchHumansgeneticsGenetic Predisposition to Disease/129lcsh:ScienceAllelesScience & Technologygenome wide associationRISK PREDICTION/45Models Geneticlcsh:RDecision Trees/692/308/2056ASSOCIATIONMultidisciplinary SciencesCrohn's diseaseLogistic ModelsNonlinear DynamicsROC CurveArea Under CurveScience & Technology - Other Topicslcsh:QFemaleNeural Networks ComputerINFLAMMATORY-BOWEL-DISEASEGenome-Wide Association StudyScientific Reports
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