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AUTHOR
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Stability and disassembly properties of human naïve Hsp60 and bacterial GroEL chaperonins.
Human Hsp60 chaperonin and its bacterial homolog GroEL, in association with the corresponding co-chaperonins Hsp10 and GroES, constitute important chaperone systems promoting the proper folding of several mitochondrial proteins. Hsp60 is also currently described as a ubiquitous molecule with multiple roles both in health conditions and in several diseases. Naïve Hsp60 bearing the mitochondrial import signal has been recently demonstrated to present different oligomeric organizations with respect to GroEL, suggesting new possible physiological functions. Here we present a combined investigation with circular dichroism and small-angle X-ray scattering of structure, self-organization, and sta…
Leach-Proof Sol–Gel Microcapsules as Curing Agents for One-Pot Thermosetting Resins
The sol-gel microencapsulation of free-radical initiator benzoyl peroxide in sol-gel methyl-modified silica microcapsules of core/shell geometry allows curing of acrylate-based polyurethane and polyester resin formulations sprayed from a pressurized can without the need to compartmentalize reactants from the initiator to cross-link. These results open the route to widespread application of sol-gel microcapsules to efficiently cure polymer and composite mixtures that are widely used as functional coatings, molding compounds, adhesives, and sealants.
Quantifying OAE2 marine oxygen levels from coupled Mo and U isotopes: A Tethyan perspective.
U and Mo isotopes are promising geochemical proxies for globally averaged ocean redox conditions in deep time. Because the Mo and U isotope compositions of seawater are controlled primarily by variation in ocean redox conditions, coupled Mo and U isotope records can be used to reconstruct variation in the relative sizes of oxic/suboxic, anoxic and euxinic sinks over geological time. The different sensitivities of Mo and U to anoxic and euxinic conditions creates a situation in which joint evaluation of the Mo and U isotope records provide greater constraints on variation in ocean redox conditions than either proxy can in isolation. Here we report new and published Mo- and U-isotope data fro…
Academic domains as political battlegrounds: A global enquiry by 99 academics in the fields of education and technology
WOS: 000401148100005
EVpedia: a community web portal for extracellular vesicles research
Abstract Motivation: Extracellular vesicles (EVs) are spherical bilayered proteolipids, harboring various bioactive molecules. Due to the complexity of the vesicular nomenclatures and components, online searches for EV-related publications and vesicular components are currently challenging. Results: We present an improved version of EVpedia, a public database for EVs research. This community web portal contains a database of publications and vesicular components, identification of orthologous vesicular components, bioinformatic tools and a personalized function. EVpedia includes 6879 publications, 172 080 vesicular components from 263 high-throughput datasets, and has been accessed more tha…
Step-by-Step Growth of HKUST-1 on Functionalized TiO2 Surface: An Efficient Material for CO2 Capture and Solar Photoreduction
The present study reports on a simple preparation strategy of a hybrid catalyst, TiO2/HKUST-1, containing TiO2 anatase nanoparticles (NPs) with tailored morphology and photocatalytic activity coupled with a porous metal-organic framework (MOF), namely HKUST-1, as an advanced material for the CO2 photocatalytic reduction. In detail, TiO2/HKUST-1 catalyst was prepared via an easy slow-diffusion method combined with a step-by-step self-assembly at room temperature. The growth of crystalline HKUST-1 onto titania surface was achieved by functionalizing TiO2 nanocrystals, with phosphoesanoic acid (PHA), namely TiO2-PHA, which provides an intimate contact between MOF and TiO2. The presence of a cr…
Interactions of fungi with other organisms.
Living organisms establish complex networks of mutualistic and antagonistic interactions in nature, which impact strongly on their own survival and on the stability of the whole population. Fungi, in particular, can shape natural as well as man-managed ecosystems due to their ubiquitous occurrence and the range of interactions they establish with plants, animals and other microbes. This review describes some examples of mutualistic and antagonistic fungal interactions that are of particular interest for their ecological role, or because they can be exploited by man to improve plant health and/or productivity in sustainable agriculture and forestry.
The Gaia-ESO Survey: Extracting diffuse interstellar bands from cool star spectra DIB-based interstellar medium line-of-sight structures at the kpc scale
We study how diffuse interstellar bands (DIBs) measured toward distance-distributed target stars can be used to locate dense interstellar (IS) clouds in the Galaxy and probe a line-of-sight (LOS) kinematical structure, a potential useful tool when gaseous absorption lines are saturated or not available in the spectral range. Cool target stars are numerous enough for this purpose. We have devised automated DIB fitting methods appropriate to cool star spectra and multiple IS components. The data is fitted with a combination of a synthetic stellar spectrum, a synthetic telluric transmission, and empirical DIB profiles. In parallel, stellar distances and extinctions are estimated self-consisten…
Jevons on the Ricardian Theory of Distribution. An Interpretation
The paper reconstructs Jevons' strategy of interpretation of Ricardian economics in the light of some hermeneutic categories. Jevons' basic goal appears to be a critical assessment of the net scientific content of Classical economics. He envisages a three steps exegetical strategy: first he points out the scientific standards all economic theories should conform to and elaborates his new economic theory in compliance with these standards; then he scrutinizes the corpus of received economic doctrines in the light of his theory and, finally, he passes his sentence. Jevons' belief that truth in economics is one prevents him to recognize that what he calls scientific errors may actually be theo…
Coronal properties of G-type stars in different evolutionary phases
We report on the analysis of XMM-Newton observations of three G-type stars in very different evolutionary phases: the weak-lined T Tauri star HD 283572, the Zero Age Main Sequence star EK Dra and the Hertzsprung-gap giant star 31 Com. They all have high X-ray luminosity (10^31 erg/s for HD 283572 and 31 Com and 10^30 erg/s for EK Dra). We compare the Emission Measure Distributions (EMDs) of these active coronal sources, derived from high-resolution XMM-Newton grating spectra, as well as the pattern of elemental abundances vs. First Ionization Potential (FIP). We also perform time-resolved spectroscopy of a flare detected by XMM from EK Dra. We interpret the observed $EMD$s as the result of …
Electroweak measurements in electron-positron collisions at W-boson-pair energies at LEP
The ALEPH, DELPHI, L3, OPAL collaborations and LEP Electroweak Working Group.-- arXiv:1302.3415
Family reunification: the case of the Muslim migrant children in Europe
Adopting a child is not a legal concept recognized in Islamic law, who however giving a great importance to orphans and children's rights, has introduced the legal institute of the "Kafala". This institute can be defined as a commitment by the "kafil" to ensure maintenance, education and protection of a minor "makfoul" until his legal majority, in the same way as would a father to his son, but without creating any family relationship. For these reasons the “Kafala” can not be compared to an international adoption, which, contrariwise, entails the creation of a parent-child relationship. If, in one side the Kafala is a legal concept recognized by International Law, in particular by the Unite…
International Law, War and Human Rights: The Humanitarian Response
One of the most important issues in the international political and legal system comprises the interaction between human rights and humanitarian law. In particular, the separate treatment of such areas of law allows to delineate different contents and application procedures, while the joint consideration is not simple, in view of the reasons for which each of the two has been created. Humanitarian law is a set of rules of conduct limited to a political and legal situation pathological, and presumably temporary. Against this regulatory system, the international law of human rights is the establishment of a political and legal concept of man as endowed with certain inalienable rights that con…