0000000000088102

AUTHOR

Julio Fernández

showing 2 related works from this author

Usefulness of Clinical Data and Biomarkers for the Identification of Frailty After Acute Coronary Syndromes

2015

Abstract Background Frailty predicts mortality after acute coronary syndrome (ACS). The standard frailty scales, such as the Fried score, consist of a variety of questionnaires and physical tests. Our aim was to investigate easily available clinical data and blood markers to predict frailty at discharge, in elderly patients after ACS. Methods A total of 342 patients older than 65 years, survivors after ACS, were included. A high number of clinical variables were collected. In addition, blood markers potentially linked to frailty and related to the processes of inflammation, coagulation, hormonal dysregulation, nutrition, renal dysfunction, and heart dysfunction were determined. Frailty was …

Malemedicine.medical_specialtyAcute coronary syndromeFrail ElderlyMyocardial InfarctionComorbidityDiseaseCohort StudiesRisk FactorsInternal medicineVitamin D and neurologyHumansMedicineMyocardial infarctionAcute Coronary SyndromeCystatin CVitamin DGeriatric AssessmentAgedAged 80 and overbusiness.industryPrognosismedicine.diseaseComorbidityPatient DischargeSurgeryPatient Outcome AssessmentHeart failureHemoglobinometryBiomarker (medicine)FemaleCardiology and Cardiovascular MedicinebusinessBiomarkersFollow-Up StudiesCohort studyCanadian Journal of Cardiology
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Frailty and other geriatric conditions for risk stratification of older patients with acute coronary syndrome

2014

Background Geriatric conditions may predict outcomes beyond age and standard risk factors. Our aim was to investigate a wide spectrum of geriatric conditions in survivors after an acute coronary syndrome. Methods A total of 342 patients older than 65 years were included. At hospital discharge, 5 geriatric conditions were evaluated: frailty (Fried and Green scores), physical disability (Barthel index), instrumental disability (Lawton-Brody scale), cognitive impairment (Pfeiffer questionnaire), and comorbidity (Charlson and simple comorbidity indexes). The outcomes were postdischarge mortality and the composite of death/myocardial infarction during a 30-month median follow-up. Results Seventy…

MaleGerontologyAcute coronary syndromemedicine.medical_specialtyFrail ElderlyMyocardial InfarctionComorbidityRisk AssessmentCohort StudiesRisk FactorsInternal medicineActivities of Daily LivingmedicineHumansProspective StudiesMyocardial infarctionAcute Coronary SyndromeGeriatric AssessmentAgedProportional Hazards ModelsAged 80 and overHand StrengthReceiver operating characteristicProportional hazards modelbusiness.industryHazard ratioPrognosismedicine.diseaseComorbidityROC CurveArea Under CurveMultivariate AnalysisExercise TestFemaleCognition DisordersCardiology and Cardiovascular MedicineRisk assessmentbusinessCohort studyAmerican Heart Journal
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