The signature of longevity in Sicily

Ageing is a natural and physiological condition that is the result of compromised stress response, homeostatic imbalance and increased risk of developing diseases. However, if aging with good health and functions (successful ageing) and aging with disease and disability (unsuccessful ageing) depends on a combination of “positive features”, including genetic, epigenetic and phenotypic characteristics in combination with favourable environment, economic status and social involvement. In our study, we summarize some key points for the identification of a longevity signature, with a particular focus on long-living Sicilian individuals and centenarians. Analysing three different Sicilian cohorts…

Profilo proteomico del polline di Parietaria judaica

Proteome profiling of mature pollen of Parietaria judaica.

Analisi proteomica del polline di Parietaria judaica

Hypoallergenic fragment of Parj 2 increases functional expression of toll like receptor in atopic children

Electrophoresis of proteins and DNA on horizontal sodium dodecyl sulfate polycrylamide gels

In vivo and in vitro effects of variants Parj2 in asthmatic children

Proteomic analysis of mature pollen grains of Parietaria judaica