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. . R

Letter to the Editor regarding the paper by Aurilio et al., A meta-analysis of oestrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 discordance between primary breast cancer and metastases

Sir,We have read with great interest the article in press ofAurilio et al., A meta-analysis of oestrogen receptor, pro-gesterone receptor and human epidermal growth factorreceptor 2 discordance between primary breast cancerand metastases (http://dx.doi.org/10.1016/j.ejca.2003.10.004), which will appear in Eur J Cancer. In the paper,the Authors have performed a meta-analysis of the stud-ies published in the literature concerning the discor-dance rate in oestrogen receptor (ER), progesteronereceptor (PgR) and HER2 status between primarytumour and corresponding relapse. It is well known thata considerable controversy concerns the issue of hor-mone receptors (HRs) expression as well as HER2 sta…

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CHANGE IN VOLUME AND MORPHOLOGY IN CULTURES OF OLEISPIRA ANTARCTICA AS A FUNCTION OF TEMPERATURE AND SUBSTRATES USED

Bacterial population under nutritional and physic stress react in order to adequate cell metabolism and physiology to stressful conditions. One of the most frequently observed behaviours in the stress-starvation response of gram-negative bacteria is the size reduction and cell morphology conversion from rod to resistant shape-form. In such framework, we report here on morphology (cell volume and cell shape) variations in psychrophilic strain Oleispira antarctica RB 8T under different growth temperature and different hydrocarbons mixtures sources. Six different hydrocarbons mixtures (car commercial diesel, commercial crude oil engine; 2 different bilge waters, military jet fuel and crude oil…

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