0000000000103879
AUTHOR
Valentina Bravata'
showing 18 related works from this author
Radiosensitizing effect of Curcumin loaded lipid nanoparticles in breast cancer cells
2016
Biomolecular Investigations in Osteoarthritis
2012
An integrative genomic and proteomic analysis in breast cancer patients negative and positive to 18F-FDG PET screening.
2011
Gene Expression Profiling of Epithelial–Mesenchymal Transition in Primary Breast Cancer Cell Culture
2014
Background/Aim: Epithelial–mesenchymal transition (EMT) is a process co-opted by cancer cells to invade and form metastases. In the present study we analyzed gene expression profiles of primary breast cancer cells in culture in order to highlight genes related to EMT. Materials and Methods: Microarray expression analysis of primary cells isolated from a specimen of a patient with an infiltrating ductal carcinoma of the breast was performed. Real-Time Quantitative Reverse Transcription PCR (qRT-PCR) analyses validated microarray gene expression trends. Results: Thirty-six candidate genes were selected and used to generate a molecular network displaying the tight relationship among them. The …
Metabolic Signature of Breast Cancer Patients Negative and Positive to 18F-FDG PET Srceening.
2011
Cell, molecular and inflammatory breast cancer response to IntraOperative Electron Radiation Therapy (IOERT)
2016
Metabolic signature of breast cancer patients negative and positive to 18F-FDG PET screening.
2010
CLINICAL, BIOMOLECULAR AND IMMUNOLOGICAL INVESTIGATION OF KNEE OSTEOARTHRITIS
2014
Introduction. Osteoarthritis (OA) is a slowly progressive disorder characterized by a gradual loss of articular cartilage. The OA classification is mainly based on clinical and radiographic evaluations, using the Knee Society Score (AKSS) and the Kellgren and Lawrence (KL) scale. Single nucleotide polymorphisms (SNPs) in frzb, matn3,aspn, pthr2, gdf5 and dvwa genes are involved in OA susceptibility. However, very few studies in Caucasian people describe the association between KL grading scale and genetical alterations. In this study we assessed the associations between KL grade, clinical features,SNPs and inflammatory mediators in Sicilian individuals Methods. We enrolled 66 patients with …
Aromatic aminoacids and Calcium Dependent Antibiotic:Relation of primary metabolism to antibiotic production in Actinomycetes
2007
Biomolecular investigation in osteoarthritis
2012
A Study of Choline and Standard Uptake Value Correlation in Discriminating IDC from ILC.
2012
A genetic study on the role of thiamine transporters in a case of atrophic Beri-Beri
2011
A putative membrane protein and an ABC-transporter of Planobispora rosea induce antibacterial activity of Streptomyces lividans
2006
Genomic and Proteomic Integrated Approach to Study Breast Cancer: Differences in Patients negative and Positive to 18F-FDG PET Screening
2012
Breast cancer rather presents distinct subtypes associated with different clinical outcomes. Understanding this heterogeneity is a key factor for the development of targeted preventative and therapeutic interventions (Rakha et al 2008). 18Ffluoro- 2-deoxy-D-glucose Positron Emission Tomography (18F-FDG PET) has been evaluated in breast cancer to characterize primary tumors, lymph node staging and patients follow-up after surgery, chemotherapy and/or external radiotherapy (Lind et al 2004). PET is a molecular imaging technique sensitive to functional or metabolic changes in tissues. Since functional changes precede anatomical changes, FDG PET has the capability to detect viable tumor tissue …
Single-nucleotide polymorphisms and FDG-PET in breast cancer. Clin Transl Imaging, 2013: 1 (Suppl 1):S6.
2013
Correlation between SUV with Partial Volume Correction and choline in breast cancer.
2012
Inflammatory Response to a High Radiation Dose in Breast Cancer
2014
Background: Radiation therapy (RT) is an essential treatment modality used for breast cancer (BC) care. Radiations can stimulate the immune system via the early activation of cytokine cascades, which can greatly affect cellular radio-sensitivity. Our aim is to analyze inflammatory response induced by high ionizing radiation (IR) doses, generated by intraoperative radiotherapy (IORT) treatment, to identify several potential targets that may influence cell radio-response. Methods: MCF10, MCF7 and MDA-MB231 BC cell lines have been exposed to high IR (23 Gray and 9 Gray), delivered by IORT treatments. Conditioned media (CM) were assayed at the time points: 0’, 30’, 1, 3, 6, 24, 48, and 72 hours…