0000000000109023

AUTHOR

Roberto Di Maio

showing 11 related works from this author

Synergistic action of CB1 and 5-HT2B receptors in preventing pilocarpine-induced status epilepticus in rats

2019

Abstract Endocannabinoids (eCBs) and serotonin (5-HT) play a neuromodulatory role in the central nervous system. Both eCBs and 5-HT regulate neuronal excitability and their pharmacological potentiation has been shown to control seizures in pre-clinical and human studies. Compelling evidence indicates that eCB and 5-HT systems interact to modulate several physiological and pathological brain functions, such as food intake, pain, drug addiction, depression, and anxiety. Nevertheless, there is no evidence of an eCB/5-HT interaction in experimental and human epilepsies, including status epilepticus (SE). Here, we performed video-EEG recording in behaving rats treated with the pro-convulsant age…

0301 basic medicineMaleCannabinoid receptormedicine.medical_treatmentPharmacologySettore BIO/09 - Fisiologia0302 clinical medicineStatus Epilepticus5-HT2BEEGStatus epilepticuPilocarpineCalcium Channel BlockersEndocannabinoid systemCB1Clinical applicationNeurologyPilocarpinemedicine.symptommedicine.drugReceptorAM251AgonistSerotoninEndocannabinoid systemmedicine.drug_classMorpholinesCannabinoid receptors; Clinical applications; EEG; Endocannabinoid system; Serotonin; Status epilepticus; Synergistic interactions; Animals; Benzoxazines; Calcium Channel Blockers; Male; Morpholines; Muscarinic Agonists; Naphthalenes; Pilocarpine; Rats; Rats Sprague-Dawley; Receptor Cannabinoid CB1; Receptor Serotonin 5-HT2B; Serotonin 5-HT2 Receptor Agonists; Status EpilepticusStatus epilepticusClinical applicationsMuscarinic AgonistsNaphthaleneslcsh:RC321-57103 medical and health sciencesmedicineAnimalsCannabinoid receptorslcsh:Neurosciences. Biological psychiatry. NeuropsychiatryCannabinoidbusiness.industryAntagonistSynergistic interactionsBenzoxazinesRats030104 developmental biologySerotoninCannabinoidSprague-Dawleybusiness030217 neurology & neurosurgerySerotonin 5-HT2 Receptor Agonists
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Geophysical study of the hydrothermal reservoir in the Panza area (Ischia, Italy)

2008

The aim of the work is the reconstruction of the main geometric pattern and the characterisation with geophysical parameters of geological structures lying at small and medium depths in an area of the Ischia island (Italy), where a sensible hydrothermal activity is present.

Settore GEO/11 - Geofisica Applicatageothermal reservoirgeophysical explorationIschia islandERT TDEM hydrotermal reservoir Ischia
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Nitric oxide/cGMP and lamotrigine/vigabatrin in a rat model of temporal lobe epilepsy

2005

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Microiontophoretic Evidence that Nitric Oxide Alters Spontaneous Activity of the Substantia Nigra Pars Reticulata Neurons in the Rat

2004

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Nitric oxide influences the activity of neurones in the subthalamic nucleus of the rat.

2006

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Effects of nitric oxide along basal ganglia pathways: a microiontophoretic study in the rat.

2006

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Lamotrigine and vigabatrin control of maximal dentate gyrus activation in the rat: role of nitric oxide(NO)/cGMP pathway

2005

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ROLE OF NITRIC OXIDE IN THE CONTROL OF MAXIMAL DENTATE GYRUS ACTIVATION BY LAMOTRIGINE IN THE RAT.

2006

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Lamotrigine and vigabatrin control of maximal dentate gyrus activation in the rat: role of nitric oxide (NO) / cGMP pathways

2005

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Caratterizzazione geofisica dell'acquiferio idrotermale dell'area di Panza (Ischia)

2007

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Nitric oxide/cGMP and Lamotrigine/Vigabatrin effects in a rat model of temporal lobe epilepsy.

2006

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