0000000000115504

AUTHOR

Courtney Lancaster

showing 1 related works from this author

Correction

2019

ABSTRACT During gastrulation, embryonic cells become specified into distinct germ layers. In mouse, this continues throughout somitogenesis from a population of bipotent stem cells called neuromesodermal progenitors (NMps). However, the degree of self-renewal associated with NMps in the fast-developing zebrafish embryo is unclear. Using a genetic clone-tracing method, we labelled early embryonic progenitors and found a strong clonal similarity between spinal cord and mesoderm tissues. We followed individual cell lineages using light-sheet imaging, revealing a common neuromesodermal lineage contribution to a subset of spinal cord tissue across the anterior-posterior body axis. An initial pop…

0303 health sciencesTailbudGastrulationCorrection205Computational biologyBiologySpinal cordImaging dataData availability03 medical and health sciences0302 clinical medicinemedicine.anatomical_structureAxial elongationmedicineMolecular BiologyZebrafish030217 neurology & neurosurgeryResearch Article030304 developmental biologyDevelopmental BiologyDevelopment (Cambridge)
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