0000000000123077

AUTHOR

Cesare Selli

showing 5 related works from this author

Adrenal myelolipoma associated with adenoma

2004

The association of an adrenal myelolipoma with a non-functioning adenoma is very rare. Herein, we report on such a case in an asymptomatic 64-year-old woman. To the best of our knowledge, there is only one other case of non-functioning adrenocortical adenoma associated with myelolipoma in the same gland. Furthermore, only two other adenomas (mineral corticoids and corticosteroid producing tumors) associated with myelolipomas have been reported, and both myelolipomas were less than 1 cm in size. In conclusion, the 8.5 cm myelolipoma in our case is the largest compared with the three previously reported ones.

MyelolipomaAdenomamedicine.medical_specialtyPathologyAdenomamedicine.drug_classUrologymedicine.medical_treatmentAdrenal Gland NeoplasmsAdrenal neoplasmAsymptomaticadenoma adrenal neoplasms adrenalectomy myelolipoma.Adrenocortical adenomaMyelolipomaInternal medicinemedicineHumansAdrenal myelolipomabusiness.industryAdrenalectomyAdrenalectomyMiddle Agedmedicine.diseaseEndocrinologyCorticosteroidFemalemedicine.symptombusiness
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Transperitoneal vs retroperitoneal minimally invasive partial nephrectomy: comparison of perioperative outcomes and functional follow-up in a large m…

2020

Abstract Background Aim of this study was to evaluate and compare perioperative outcomes of transperitoneal (TP) and retroperitoneal (TR) approaches in a multi-institutional cohort of minimally invasive partial nephrectomy (MI-PN). Material and methods All consecutive patients undergone MI-PN for clinical T1 renal tumors at 26 Italian centers (RECORd2 project) between 01/2013 and 12/2016 were evaluated, collecting the pre-, intra-, and postoperative data. The patients were then stratified according to the surgical approach, TP or RP. A 1:1 propensity score (PS) matching was performed to obtain homogeneous cohorts, considering the age, gender, baseline eGFR, surgical indication, clinical dia…

medicine.medical_specialtyIntraoperative ComplicationUrologymedicine.medical_treatmentOperative TimeSurgical approach030232 urology & nephrologyMinimally invasive partial nephrectomy Renal cell carcinoma Retroperitoneal Surgical approach Transperitoneal.lcsh:RC870-923lcsh:RC254-282NephrectomyArticle03 medical and health sciences0302 clinical medicineRenal cell carcinomamedicineMinimally invasive partial nephrectomy; Renal cell carcinoma; Retroperitoneal; Surgical approach; TransperitonealHumansRetroperitoneal SpaceRetrospective StudiesMinimally invasive partial nephrectomybusiness.industryRenal cell carcinoma; Minimally invasive partial nephrectomy; Transperitoneal; Retroperitoneal; Surgical approachTransperitonealPerioperativeRetroperitoneallcsh:Diseases of the genitourinary system. Urologylcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseaseNephrectomyKidney NeoplasmsRenal cell carcinomaSurgerySettore MED/24Treatment Outcome030220 oncology & carcinogenesisPropensity score matchingCohortSurgeryLaparoscopyPositive Surgical MarginMinimally invasive partial nephrectomy; Renal cell carcinoma; Retroperitoneal; Surgical approach; Transperitoneal; Follow-Up Studies; Humans; Nephrectomy; Operative Time; Retroperitoneal Space; Retrospective Studies; Treatment Outcome; Kidney Neoplasms; LaparoscopybusinessAbdominal surgeryFollow-Up StudiesSurgical endoscopy
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Predicting positive surgical margins in partial nephrectomy: A prospective multicentre observational study (the RECORd 2 project)

2020

PURPOSE: to evaluate clinical predictors of positive surgical margins (PSMs) in a large multicenter prospective observational study and to develop a clinic nomogram to predict the likelihood of PSMs after partial nephrectomy (PN). MATERIALS AND METHODS: We prospectively evaluated 4308 patients who had surgical treatment for renal tumors between January 2013 and December 2016 at 26 urological Italian Centers (RECORd 2 project). Two multivariable logistic models were evaluated to predict the likelihood of PSMs. Center caseload was dichotomized using a visual assessment adjusted for several predictors of PSMs. A nomogram predicting PSMs was developed. RESULTS: Overall, 2076 patients treated wi…

MaleNeoplasm ResidualDatabases Factualmulticenter prospective observational studymedicine.medical_treatment030232 urology & nephrologyNephron-sparing surgeryNephrectomyNomogram0302 clinical medicineRenal cell carcinomaRisk Factorsclinical predictorPartial nephrectomyProspective StudiesStage (cooking)Prospective cohort studySurgical margins Nephron-sparing surgery Nomogram Partial nephrectomy Renal cell carcinoma Robot-assisted partial nephrectomySurgical marginsRobot-assisted partial nephrectomyMargins of ExcisionGeneral MedicineMiddle AgedNephrectomyKidney NeoplasmsHospitalsRenal cell carcinomaOncologyElective Surgical Procedures030220 oncology & carcinogenesisArea Under CurveResidualNephron-sparing surgery; Nomogram; Partial nephrectomy; Renal cell carcinoma; Robot-assisted partial nephrectomy; Surgical marginsFemalepositive surgical marginPositive Surgical MarginElective Surgical Proceduremedicine.medical_specialtyHospitals Low-VolumeHigh-Volume03 medical and health sciencesDatabasesSurgical margins; Nephron-sparing surgery; Nomogram; Partial nephrectomy; Renal cell carcinoma; Robot-assisted partial nephrectomyInternal medicineLow-VolumemedicineHumansNeoplasm InvasivenessCarcinoma Renal CellFactualAgedNeoplasm Stagingbusiness.industryCarcinomaRenal CellNomogrammedicine.diseaseNomogramsSettore MED/24Logistic ModelsROC CurveNeoplasmSurgeryObservational studybusinessHospitals High-Volume
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p53 and Ki-67 expression in renal cell carcinomas of pregnant women and their correlation with prognosis: a pilot study.

2007

In the present study, we reported two cases of renal cell carcinoma (RCC) diagnosed in pregnant women (Pt) that were submitted to radical nephrectomy, in both cases within the fourth month. The patients, after 13 and 3 years, respectively, did not show evidence of recurrent disease. We performed an immunohistochemical study on RCC specimens in comparison to seven age-matched controls (Cl). The panel of antibodies included Ki-67, p53, bcl-2, ER, PgR, PCNA, and IGF-1. We describe a difference in the expression of p53 and Ki-67. Specifically, p53 was highly expressed in RCC of both Pt but scarcely present or absent in Cl; by contrast, Ki-67 was hardly expressed or negative in RCC of both Pt, b…

Adultmedicine.medical_specialtyPathologymedicine.medical_treatmentPilot ProjectsDiseaseGastroenterologyNephrectomyImmunoenzyme Techniquescarcinomas prognosisRenal cell carcinomaPregnancyInternal medicinemedicineBiomarkers TumorHumansCarcinoma Renal CellKEYWORDS: IGF-1 Ki-67 pregnancy p53 protein renal cell carcinoma.Pregnancybiologybusiness.industryObstetrics and Gynecologymedicine.diseasePrognosisNephrectomyKidney NeoplasmsProliferating cell nuclear antigenKi-67 AntigenOncologyKi-67biology.proteinImmunohistochemistryFemalePregnant WomenAntibodyTumor Suppressor Protein p53businessPregnancy Complications Neoplastic
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Primitive Neuroectodermal Tumor (PNET) of the kidney: a case report.

2004

Abstract Background A case of Primitive Neuroectodermal Tumor (PNET) of the kidney in a 27-year-old woman is presented. Few cases are reported in the literature with a variable, nonspecific presentation and an aggressive behaviour. In our case, a radical nephrectomy with lymphadenectomy was performed and there was no residual or recurrent tumour at 24-month follow-up. Methods The surgical specimens were formalin-fixed and paraffin embedded. The sections were stained with routinary H&E. Immunohistochemistry was performed. Results The immunohistochemical evaluation revealed a diffuse CD99 positivity in the cytoplasm of the neoplastic cells. Pankeratin, cytokeratin AE1/AE3, vimentin, desmin, S…

AdultEwing's SarcomaPNETCancer ResearchPathologymedicine.medical_specialtyRenal PNETmedicine.medical_treatmentCD99Case Reportlcsh:RC254-282Diagnosis DifferentialCytokeratinImmunophenotypingSurgical oncologystem cellsGeneticsmedicineHumansNeuroectodermal Tumors Primitive Peripheralrhabdomyosarcoma tumorbusiness.industryEwing's sarcomalcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseaseNephrectomyKidney NeoplasmsOncologyPrimitive neuroectodermal tumorFemaleDifferential diagnosisbusinesscarcinogenesis
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