0000000000132990
AUTHOR
Giuseppe Currò
Retention strength of ball-attachment titanium post for removable partial denture or overdenture
Aim: To evaluate the retention of an endodontic titanium post with a spherical head for removable partial denture or overdenture attachment according to surface treatment type. Methods: Sixty healthy single-rooted teeth, sectioned at the enamel/cementum junction, were treated endodontically and steadily fixed in the embedding acrylic resin. The titanium posts were subdivided into four groups: control, no surface treatment (Ctrl); posts with macro-retentive grooves (MR); air abrasion of the post surface (AB); and posts with macro-retentive grooves and air abrasion of the post surface (MR+AB). The posts were luted in the root canal using self-adhesive dual resin cement. Pull-out testing was p…
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
Background: Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods: This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, r…
Are Long Noncoding RNAs New Potential Biomarkers in Gastrointestinal Stromal Tumors (GISTs)? The Role of H19 and MALAT1
Long noncoding RNAs (lncRNAs) are emerging as key regulators of genetic and epigenetic networks, and their deregulation may underlie complex diseases, such as carcinogenesis. Several studies described lncRNA alterations in patients with solid tumors. In particular, HOTAIR upregulation has been associated with tumor aggressiveness, metastasis, and poor survival in gastrointestinal stromal tumor (GIST) patients. We analyzed expression levels of other lncRNAs, H19 and MALAT1, in FFPE tissue specimens from 40 surgically resected and metastatic GIST patients, using real-time PCR analysis. H19 and MALAT1 were both upregulated in 50% of GIST patients. MALAT1 lncRNA expression levels seem to be cor…
Why laparoscopists may opt for three-dimensional view: a summary of the full HTA report on 3D versus 2D laparoscopy by S.I.C.E. (Società Italiana di Chirurgia Endoscopica e Nuove Tecnologie)
Background Three-dimensional view in laparoscopic general, gynaecologic and urologic surgery is an efficient, safe and sustainable innovation. The present paper is an extract taken from a full health technology assessment report on three-dimensional vision technology compared with standard two-dimensional laparoscopic systems. Methods A health technology assessment approach was implemented in order to investigate all the economic, social, ethical and organisational implications related to the adoption of the innovative three-dimensional view. With the support of a multi-disciplinary team, composed of eight experts working in Italian hospitals and Universities, qualitative and quantitative d…
Ortodonzia estetica: vantaggi e limiti della tecnica Invisalign
Riassunto Obiettivi Lo scopo di questo lavoro e definire vantaggi e limiti della tecnica Invisalign rispetto a metodiche ortodontiche tradizionali. Materiali e metodi E stata condotta una revisione sistematica della letteratura attraverso l’uso di diversi database, come MedLine, PubMed, Scopus. La ricerca copre il periodo che intercorre tra il 2000 e il 2011. Altre fonti sono state selezionate dai riferimenti bibliografici citati nei lavori consultati. Risultati e conclusioni La ricerca scientifica ha portato negli anni allo sviluppo di soluzioni atte a soddisfare esigenze estetiche e funzionali, a partire dai bracket in ceramica e dalla tecnica linguale fino ad arrivare negli anni Novanta …
Acupuncture in the treatment of temporomandibular disorders, facial pain, and postural neuromuscular disorders. Presentation of a clinical case
Abstract Background and objectives Temporomandibular disorders have a multifactorial etiology and involve the masticatory muscles, temporomandibular joint and associated structures. Therefore, different treatments are proposed and used. The aim of this paper is the use of acupuncture to treat temporomandibular disorders and associated symptoms. This article presents a clinical case study of a 39-year-old patient who presented temporomandibular disorders and headache of muscular origin. Results After 10 acupuncture sessions, the results were highly satisfactory, with complete relief of headache pain and absence of joint disorders. These results suggest the efficacy of acupuncture in the symp…
How to Deal with Second Line Dilemma in Metastatic Colorectal Cancer? A Systematic Review and Meta-Analysis
Monoclonal antibodies targeting epidermal growth factor receptor (EGFR) or vascular endothelial growth factor (VEGF) have demonstrated efficacy with chemotherapy (CT) as second line treatment for metastatic colorectal cancer (mCRC). The right sequence of the treatments in all RAS (KRAS/NRAS) wild type (wt) patients has not precisely defined. We evaluated the impact of aforementioned targeted therapies in second line setting, analyzing efficacy and safety data from phase III clinical trials. We performed both direct and indirect comparisons between anti-EGFR and anti-VEGF. Outcomes included disease control rate (DCR), objective response rate (ORR), progression-free survival (PFS), overall su…
Validity and reliability of measurements of the parameters of smile aesthetics: a comparison between digital and plaster models
This study aims to evaluate the validity and reliability of the TRIOS3 Color intraoral scanner (3Shape A/S, Copenhagen, Denmark) and its associated Ortho Analyzer™ software in measuring parameters of smile aesthetics compared with measurements on plaster casts. The study sample comprised plaster casts and digital models obtained from 30 subjects. Height (H), mesiodistal diameter (MDD) and connecting space (CS) of the anterior teeth were measured with a digital calliper on the plaster models and with the orthodontic software on the digital models. Validity was assessed using a 2-tailed paired t-test; the reliability of measurements for intra-examiner was evaluated with the Intra-class Correl…
Quantitative and Qualitative in vivo Analysis of Metal Residuals in the Saliva of Subjects with and without Fixed Orthodontic Appliances
Aim of the Work: The aim of this work was to evaluate Ni e Cr ions in the saliva of subjects with and without fixed orthodontic appliances. Materials and Methods: This was a prospective, non-randomized study of 100 patients, so selected: 50 have undergone fixed orthodontic appliance at least from 24 months; others 50 subjects as control-group, without any fixed and/or removable orthodontic appliance It was conducted according to the Declaration of the World Medical Association of Helsinki. The two selected groups were compatible for age, sex, absence of restoration in amalgam or other metals in the oral cavity. The saliva of all the subjects was collected with standardized sterile methods. …
Transverse Asymmetries of the Maxilla Even in Healthy and Apparently Symmetrical Subjects
In the formulation of an orthodontic treatment plan, the three-dimensional analysis of the dental arches represents a fundamental moment for the evaluation of all the morphological parameters necessary in order to have a correct and complete diagnosis. In this regard, the study of the dental arches on the horizontal plane is sometimes neglected or not thorough enough. When evaluating the transverse dimensions of the dental upper arche, the presence of an asymmetry is frequently found, and it means that an hemiarch is larger than the other. Furthermore, any variation in one of the three planes of space always involves an alteration also on the other two planes in order to have compensation. …