0000000000133468
AUTHOR
José Luis Llisterri
Additional file 1 of Cardiovascular risk factors and the impact on prognosis in patients with chronic kidney disease secondary to autosomal dominant polycystic kidney disease
Additional file 1.
Prevalencia de fibrilación auricular y uso de fármacos antitrombóticos en el paciente hipertenso ≥ 65 años. El registro FAPRES.
Introduccion y objetivos Entre los principales factores asociados a la presencia de fibrilacion auricular y mayor riesgo embolico estan la edad y la hipertension arterial. Nuestro objetivo es conocer la prevalencia de fibrilacion auricular en el paciente hipertenso de 65 o mas anos de edad en la Comunidad Valenciana y el empleo de farmacos antitromboticos. Metodos Cada investigador incluyo a los primeros 3 pacientes hipertensos de edad ≥ 65 anos que acudian a la consulta el primer dia de la semana durante 5 semanas. Se recogieron los factores de riesgo, la historia cardiovascular, la puntuacion CHADS2 y el tratamiento farmacologico y se realizo un electrocardiograma para su analisis central…
Prevalencia de filtrado glomerular disminuido en la población española de edad avanzada. Estudio PREV-ICTUS
Fundamento y objetivo Estimar la prevalencia de filtrado glomerular (FG) disminuido ( Pacientes y metodo Se analizo el estudio PREV-ICTUS, realizado en una muestra de individuos de 60 anos o mas seleccionada aleatoriamente, estratificada por comunidades autonomas segun el censo y el habitat de atencion. Se recogieron datos demograficos, factores de riesgo y enfermedades cardiovasculares. Se calculo el FG utilizando la formula de MDRD (Modification of Diet in Renal Disease). Resultados En 6.799 individuos (edad media 71,9 anos; 53,6% mujeres; 72,9% con hipertension arterial [HTA]; 27,0% con diabetes mellitus [DM]; 24,3% con enfermedad cardiovascular), el 25,9% presento FG disminuido (interva…
Losartan reduces microalbuminuria in hypertensive microalbuminuric type 2 diabetics.
Background. The aim of the present study was to assess the antialbuminuric effect of losartan in a large number of hypertensive type 2 diabetics. Methods. This was a 6-month, open-label, prospective and multicentre study. A total of 422 patients with type 2 diabetes who were hypertensive [sitting systolic blood pressure (SBP) > 140 mmHg and/or diastolic blood pressure (DBP) ≥90 mmHg] and microalbuminuric [urinary albumin excretion (UAE) 30-300 mg/day] were eligible for the study. After a 2-week run-in period, patients were placed on losartan 50 mg once a day. If the BP did not reach the desired goal (<140/90 mmHg) after a 4-week period, the losartan dose was doubled. In the absence of contr…
Gender differences related to the presence of atrial fibrillation in older hypertensive patients
AIM: To determine whether there are gender differences in the epidemiological profile of atrial fibrillation (AF) and to characterise the clinical, biochemical, and therapeutic factors associated with AF. METHODS: Each investigator (primary care physicians or physicians based in hospital units for hypertension treatment) recruited the first 3 patients with an age of ≥ 65 years and a clinical diagnosis of hypertension (ambulatory blood pressure monitoring and an electrocardiogram, were performed) on the first working day of the week for 5 wk and identified those individuals with atrial fibrillation. A binary logistic regression was performed, including all of the variables that were signific…
Perioperative and Periprocedural Management of Antithrombotic Therapy: Consensus Document of SEC, SEDAR, SEACV, SECTCV, AEC, SECPRE, SEPD, SEGO, SEHH, SETH, SEMERGEN, SEMFYC, SEMG, SEMICYUC, SEMI, SEMES, SEPAR, SENEC, SEO, SEPA, SERVEI, SECOT and AEU
During the last few years, the number of patients receiving anticoagulant and antiplatelet therapy has increased worldwide. Since this is a chronic treatment, patients receiving it can be expected to need some kind of surgery or intervention during their lifetime that may require treatment discontinuation. The decision to withdraw antithrombotic therapy depends on the patient's thrombotic risk versus hemorrhagic risk. Assessment of both factors will show the precise management of anticoagulant and antiplatelet therapy in these scenarios. The aim of this consensus document, coordinated by the Cardiovascular Thrombosis Working Group of the Spanish Society of Cardiology, and endorsed by most o…
Differences in blood pressure control and stroke mortality across Spain: the Prevención de Riesgo de Ictus (PREV-ICTUS) study.
The objective was to assess the stroke risk and prevalence of the cardiovascular risk factors and to analyze their relationship with the specific stroke rates of mortality in each of the autonomic communities of Spain. We conducted a multicenter, cross-sectional study of population >60 years old in Spanish primary care centers. In all of the subjects, clinical, biochemical, and electrocardiographic data were obtained, and the 10-year stroke risk was calculated using the Framingham score. Mortality rates of stroke, age and sex adjusted, were obtained for each of the autonomic communities from the Ministry of Health. A total of 7343 subjects (mean age: 71.6 years, 53.4% women, 34.4% obese…
Prevalencia de sobrepeso y obesidad en población española de 60 años o más y factores relacionados. Estudio PREV-ICTUS
Fundamento y objetivo: Los datos sobre prevalencia de obesidad en poblacion de edad avanzada en Espana son escasos. El objetivo de este trabajo ha sido describir la prevalencia de obesidad y los factores relacionados en una muestra aleatoria de la poblacion espanola de 60 anos o mas, estratificada por comunidades autonomas (CC.AA.). Sujetos y metodo: Se analizo el estudio PREV-ICTUS, realizado en una muestra seleccionada aleatoriamente entre septiembre y diciembre de 2005, estratificada por CC.AA. segun el censo y el habitat de atencion. Se clasifico a los sujetos segun su indice de masa corporal (IMC) en aquellos con peso normal (IMC < 25), sobrepeso (IMC de 25-29,9) y obesos (IMC $ 30). R…
Cardiovascular risk factors and the impact on prognosis in patients with chronic kidney disease secondary to autosomal dominant polycystic kidney disease
Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent hereditary renal disease. There is an increased rate of cardiovascular disease (CVD) in ADPKD. In this study, we evaluate the prevalence of cardiovascular risk factors, the achievement rates for treatment goals and cardiovascular events (CVE) in ADPKD and their relations with asymptomatic CVD in CKD from other etiologies (CKDoe) and controls. Methods: We evaluated 2445 CKD patients (2010–2012). The information collected was: clinical, anthropometric and analytical parameters, treatments and CVD evaluation (intima-media thickness (IMT), atheromatous plaque presence and ankle-brachial index (ABI)). Laborator…
Prevalencia de fibrilación auricular en la población española de 60 o más años de edad. Estudio PREV-ICTUS
Introduction and objectives. The aims of this study were to determine the prevalence of atrial fibrillation in individuals aged 60 years or more in Spain using a random sample of the population and to identify associated factors. Methods. An analysis of the PREV-ICTUS study, a randomized cross-sectional population-based study of individuals aged 60 years or more, was carried out. Data on demographic variables, cardiovascular risk factors, and cardiovascular disease were obtained from medical records. The diagnosis of atrial fibrillation was based on the patient’s medical history and an electrocardiogram performed during the study. Results. In the 7108 individuals studied (mean age, 71.9 [7.…
Prevalencia del síndrome metabólico en la población española de 60 años o más. Estudio de base poblacional PREV-ICTUS
Resumen Fundamento y objetivos se dispone de poca informacion sobre el sindrome metabolico (SM) en poblacion de edad avanzada. Los objetivos de este estudio han sido estimar su prevalencia en poblacion general espanola de 60 anos o mas y los factores asociados. Pacientes y metodo se realizo un estudio transversal de ambito poblacional en una muestra aleatoria y representativa de individuos de 60 anos o mas de todo el territorio espanol, estratificada por comunidades autonomas segun censo y habitat de residencia, entre septiembre y diciembre de 2005. Se recogieron datos sociodemograficos, clinicos, bioquimicos y electrocardiograficos. Para la definicion del SM se utilizaron los criterios del…
Blood pressure and estimated risk of stroke in the elderly population of Spain: the PREV-ICTUS study.
Background and Purpose— The objective of this study was to estimate the high blood pressure values and the 10-year risk of stroke in the Spanish general population aged 60 years or older using the Framingham scale. Methods— This was a multicenter, population-based, cross-sectional study performed in Spanish primary care centers. A randomized selection of centers and recruitment population was used. We collected clinical, biochemical, and electrocardiographic data. Results— We analyzed 7343 subjects (mean age, 71.6 years; standard deviation, 7.0; 53.4% females, 34.4% obese subjects, and 27.1% diabetic subjects). Electrocardiographic–left ventricle hypertrophy was present in 12.9% of the sub…