0000000000133732

AUTHOR

Gemma Castillejo

showing 3 related works from this author

Non-Celiac Gluten Sensitivity: The New Frontier of Gluten Related Disorders

2013

Non Celiac Gluten sensitivity (NCGS) was originally described in the 1980s and recently a “re-discovered” disorder characterized by intestinal and extra-intestinal symptoms related to the ingestion of gluten-containing food, in subjects that are not affected with either celiac disease (CD) or wheat allergy (WA). Although NCGS frequency is still unclear, epidemiological data have been generated that can help establishing the magnitude of the problem. Clinical studies further defined the identity of NCGS and its implications in human disease. An overlap between the irritable bowel syndrome (IBS) and NCGS has been detected, requiring even more stringent diagnostic criteria. Several studies sug…

medicine.medical_specialtySettore MED/09 - Medicina InternaGlutensNon-celiac gluten sensitivitylcsh:TX341-641ReviewDiseaseGastroenterologyIrritable Bowel SyndromeDiet Gluten-Freegluten-free dietTerminology as TopicNon-celiac gluten sensitivity; gluten related disordersInternal medicineEpidemiologymedicineHumansAutistic DisorderIntestinal MucosaIrritable bowel syndromeRandomized Controlled Trials as Topicchemistry.chemical_classificationNutrition and Dieteticsbusiness.industrygluten related disordersgluten sensitivitymedicine.diseaseGlutenwheat allergyIntestinal DiseaseschemistrySchizophreniaImmunologySchizophreniaAutismGluten freebusinessgluten-related disorderslcsh:Nutrition. Foods and food supplyWheat allergyceliac diseaseFood Science
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The Overlapping Area of Non-Celiac Gluten Sensitivity (NCGS) and Wheat-Sensitive Irritable Bowel Syndrome (IBS): An Update

2017

Gluten-related disorders have recently been reclassified with an emerging scientific literature supporting the concept of non-celiac gluten sensitivity (NCGS). New research has specifically addressed prevalence, immune mechanisms, the recognition of non-immunoglobulin E (non-IgE) wheat allergy and overlap of NCGS with irritable bowel syndrome (IBS)-type symptoms. This review article will provide clinicians with an update that directly impacts on the management of a subgroup of their IBS patients whose symptoms are triggered by wheat ingestion.

0301 basic medicinemedicine.medical_specialtySettore MED/09 - Medicina InternaGlutensamylase-trypsin inhibitors (ATIs)Gluten sensitivitylcsh:TX341-641Non-Celiac Gluten SensitivityReviewWheat HypersensitivityGastroenterologyIrritable Bowel Syndrome03 medical and health sciencesDiet Gluten-Free0302 clinical medicineMalabsorption Syndromesgluten-free dietMedizinische FakultätInternal medicineMedicineHumansddc:610Irritable bowel syndromeImmune mechanismsRandomized Controlled Trials as Topicgluten-related disorder030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industrygluten sensitivitynutritional and metabolic diseasesGluten-related disordersWheat-Sensitive Irritable Bowel Syndromemedicine.diseaseMalabsorption Syndromedigestive system diseasesNon-Celiac Gluten Sensitivity; Wheat-Sensitive Irritable Bowel SyndromeReview articlewheat allergy030211 gastroenterology & hepatologybusinessNon-celiac gluten sensitivitygluten-related disorderslcsh:Nutrition. Foods and food supplyWheat allergyGlutenceliac diseaseFood ScienceHuman
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Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts’ Criteria

2015

Non-Celiac Gluten Sensitivity (NCGS) is a syndrome characterized by intestinal and extra-intestinal symptoms related to the ingestion of gluten-containing food, in subjects that are not affected by either celiac disease or wheat allergy. Given the lack of a NCGS biomarker, there is the need for standardizing the procedure leading to the diagnosis confirmation. In this paper we report experts' recommendations on how the diagnostic protocol should be performed for the confirmation of NCGS. A full diagnostic procedure should assess the clinical response to the gluten-free diet (GFD) and measure the effect of a gluten challenge after a period of treatment with the GFD. The clinical evaluation i…

Diagnosis; Non-Celiac Gluten SensitivityPediatricsmedicine.medical_specialtySettore MED/09 - Medicina InternaGlutensdiagnosislcsh:TX341-641DiseasePlaceboArticleDiet Gluten-FreeDouble-Blind MethodRating scaleSurveys and QuestionnairesHumansMedicineIntestinal MucosaIrritable bowel syndromedouble-blind placebo-controlled challengechemistry.chemical_classificationirritable bowel syndromeCross-Over StudiesNutrition and Dieteticsbusiness.industrynon-celiac gluten sensitivitygastrointestinal symptom rating scalenutritional and metabolic diseasesmedicine.diseaseGlutenCrossover studySurgerychemistryImmunoglobulin GBiomarker (medicine)businesslcsh:Nutrition. Foods and food supplyBiomarkersFood HypersensitivityWheat allergyFood ScienceDiagnosiNutrients
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