0000000000135657

AUTHOR

Nicola De’angelis

0000-0002-1211-4916

showing 18 related works from this author

Emergency abdominal surgery after solid organ transplantation: a systematic review

2016

Aims: Due to the increasing number of solid organs transplantations, emergency abdominal surgery in transplanted patients is becoming a relevant challenge for the general surgeon. The aim of this systematic review of the literature is to analyze morbidity and mortality of emergency abdominal surgery performed in transplanted patients for graft-unrelated surgical problems. Methods: The literature search was performed on online databases with the time limit 1990–2015. Studies describing all types of emergency abdominal surgery in solid organ transplanted patients were retrieved for evaluation. Results: Thirty-nine case series published between 1996 and 2015 met the inclusion criteria and were…

medicine.medical_specialtymedicine.medical_treatmentGallbladder diseaseReviewHeart transplantation030230 surgeryLiver transplantationKidney transplantation03 medical and health sciences0302 clinical medicineSolid organ transplantationMedicineLung transplantationGeneral surgeryKidney transplantationEmergency abdominal surgeryLiver transplantationbusiness.industryGeneral surgeryEmergency abdominal surgery General surgery Solid organ transplantation Liver transplantation Kidney transplantation Heart transplantation Lung transplantation Systematic reviewDiverticulitismedicine.diseaseAppendicitisSurgeryTransplantationSettore MED/18 - Chirurgia GeneraleLung transplantationSystematic reviewEmergency Medicine030211 gastroenterology & hepatologySurgerybusinessAbdominal surgery
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Robotic Versus Laparoscopic Gastric Resection for Primary Gastrointestinal Stromal Tumors5 cm: A Size-Matched and Location-Matched Comparison.

2017

This study compared robotic (RR) and laparoscopic resection (LR) for primary gastrointestinal stromal tumors (GISTs) of the stomach >5 cm. Twelve consecutive patients who underwent RR from 2012 to 2015 were matched for tumor size and location with 24 patients who underwent LR from 2000 to 2012. The median tumor size was 7.1 cm (range, 5.5 to 11.5). GISTs were resected by wedge resection (91.7%) or distal gastrectomy. The median RR operative time was longer than that of LR (162.5 vs. 130 min, respectively; P=0.004). Only 1 LR patient required conversion. The time to flatus and hospital stay were similar between groups. Overall, 3 patients developed minor postoperative complications that w…

AdultMalemedicine.medical_specialtyStromal cellGastrointestinal Stromal TumorsOperative TimeBlood Loss Surgical030230 surgeryRobotic gastric resectionRisk Assessment03 medical and health sciences0302 clinical medicinePostoperative ComplicationsRobotic Surgical ProceduresStomach Neoplasmslaparoscopic gastric resectionmedicineHumansLaparoscopic resectionGastric resectionUltrasonography InterventionalAgedAged 80 and overTumor sizebusiness.industryStomachIncidence (epidemiology)Length of StayMiddle AgedSurgerySettore MED/18 - Chirurgia Generalemedicine.anatomical_structureTreatment OutcomeSurgery Computer-Assisted030220 oncology & carcinogenesisCosts and Cost AnalysisOperative timeSurgeryFemaleLaparoscopybusinessprimary gastrointestinal stromal tumorGISTWedge resection (lung)Surgical laparoscopy, endoscopypercutaneous techniques
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Emergency Colorectal Surgery Checklist and Technical Considerations

2019

A surgical checklist is a step-by-step control procedure carried on for checking through the most delicate phases of the perioperative period, in order to increase surgical patient’s safety and avoid preventable complications. The checklist implementation within operating rooms have proved to be effective in reducing morbidity and mortality rates significantly, without being costly and lengthy. These results have been confirmed also in emergency surgery, which represents in itself a cause of higher risks for patients. Thus, the checklist use has rapidly spread out all over the world. The mechanism responsible for the improvement of surgical outcomes is not completely clear, partly due to am…

Surgical teammedicine.medical_specialtySurgical Safety Checklistbusiness.industryEmergency colorectal surgeryPatient positioningPerioperativemedicine.diseaseColorectal surgeryChecklistSettore MED/18 - Chirurgia GeneraleEmergency surgerymedicineMedical emergencySurgical checklistbusinessSurgical patients
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What is the best surgical option for the resection of transverse colon cancer?

2019

Transverse colon is an infrequent localization of colon cancer and it is burdened by a poor prognosis. The principle of oncological radicality includes primary tumor resection with adequate lymphadenectomy. To date, there is still no consensus on which type of surgical resection perform in case of transverse colon cancer (TCC). Lymphatic drainage and vascularization of this section of the colon is highly variable presenting with different anatomical variants. Moreover, mobilization of the transverse colon can be particularly challenging in comparison to other colon tracts. Despite a lack of standardized definitions, three main surgical options are proposed: segmental colectomy of the transv…

Poor prognosismedicine.medical_specialtybusiness.industryColorectal cancermedicine.medical_treatmentTransverse colon cancer (TCC)Transverse colonmedicine.diseasePrimary tumorextended colectomy (EC)Resectiontransverse colectomy (TC)Transverse ColectomyMedicineSurgeryLymphadenectomyRadiologybusinessTransverse colon cancersubtotal colectomy (STC)
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Incidence and predictors of portal and splenic vein thrombosis after pure laparoscopic splenectomy.

2017

Background. Optimal modalities for diagnosis, treatment, and surveillance of portal or splenic vein thrombosis have not yet been defined. The present retrospective study aimed to investigate the role of computed tomography performed systematically before and after laparoscopic splenectomy to assess the incidence of portal or splenic vein thrombosis, predictors, and outcomes. Methods. Computed tomography scans were obtained from 170 patients undergoing elective laparoscopic splenectomy between 2005 and 2015. Pre- and postoperative splenic vein diameter was measured at the splenoportal junction and at a distance of 2, 4, 6 cm from it. Univariate and multivariate analyses were used to identify…

Malemedicine.medical_treatment030230 surgery0302 clinical medicinePostoperative ComplicationsRisk FactorsLaparoscopyAged 80 and overVenous Thrombosismedicine.diagnostic_testPortal VeinIncidenceMiddle Agedsplenic vein thrombosiTreatment Outcomecardiovascular systemSplenectomy030211 gastroenterology & hepatologyFemaleRadiologymedicine.symptomAdultmedicine.medical_specialtyAdolescentSplenectomylaparoscopic splenectomyAsymptomaticPerioperative Care03 medical and health sciencesYoung AdultmedicineHumansThrombusPortal vein thrombosiAgedRetrospective Studiesbusiness.industryRetrospective cohort studycomputed tomographyOdds ratiomedicine.diseaseSurgerySettore MED/18 - Chirurgia GeneraleLogistic ModelsSplenic veinSplenic VeinAsymptomatic DiseasesSurgeryLaparoscopybusinessComplicationTomography X-Ray ComputedFollow-Up StudiesSurgery
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2017 WSES guidelines for the management of iatrogenic colonoscopy perforation

2017

Abstract Iatrogenic colonoscopy perforation (ICP) is a severe complication that can occur during both diagnostic and therapeutic procedures. Although 45–60% of ICPs are diagnosed by the endoscopist while performing the colonoscopy, many ICPs are not immediately recognized but are instead suspected on the basis of clinical signs and symptoms that occur after the endoscopic procedure. There are three main therapeutic options for ICPs: endoscopic repair, conservative therapy, and surgery. The therapeutic approach must vary based on the setting of the diagnosis (intra- or post-colonoscopy), the type of ICP, the characteristics and general status of the patient, the operator’s level of experienc…

MaleIatrogenic DiseaseColonoscopyReviewIatrogenic colonoscopy perforation0302 clinical medicine80 and overOpen abdomenAged 80 and overintegumentary systemmedicine.diagnostic_testmusculoskeletal neural and ocular physiologylcsh:Medical emergencies. Critical care. Intensive care. First aidDisease ManagementIatrogenic colonoscopy perforation Colonoscopy Gastrointestinal endoscopy Emergency surgery Laparoscopy Antibiotic therapy Intra-abdominal infection Open abdomenColonoscopyMiddle Agedhumanities030220 oncology & carcinogenesisEmergency surgeryEmergency MedicineFemale030211 gastroenterology & hepatologymedicine.medical_specialtyColonPerforation (oil well)lcsh:SurgeryGuidelines as TopicSigns and symptomsGeneral status03 medical and health sciencesTherapeutic approachIntra-abdominal infectionEmergency surgerymedicineHumansGastrointestinal endoscopyIntensive care medicineAgedbusiness.industrylcsh:RD1-811lcsh:RC86-88.9Antibiotic therapyEndoscopic Procedurenervous system diseasesSettore MED/18 - Chirurgia GeneraleIntestinal PerforationAntibiotic therapy; Colonoscopy; Emergency surgery; Gastrointestinal endoscopy; Iatrogenic colonoscopy perforation; Intra-abdominal infection; Laparoscopy; Open abdomen; Aged; Aged 80 and over; Colon; Colonoscopy; Disease Management; Female; Humans; Intestinal Perforation; Male; Middle Aged; Guidelines as Topic; Iatrogenic DiseaseAntibiotic therapy; Colonoscopy; Emergency surgery; Gastrointestinal endoscopy; Iatrogenic colonoscopy perforation; Intra-abdominal infection; Laparoscopy; Open abdomen;LaparoscopySurgerySurgical devicebusiness
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Comparison of Different Nodal Staging in Patients With Locally Advanced Mid-low Rectal Cancer After Long-term Neoadjuvant Chemoradiation Therapy.

2019

Background/Aim: The aim of this study was to compare the ability of different lymph nodal staging systems to predict cancer recurrence in a multicenter European series of patients who underwent proctectomy after neoadjuvant chemoradiotherapy for locally advanced rectal cancer. Patients and Methods: Data on 170 consecutive patients undergoing proctectomy after neoadjuvant therapy for cT3-4 or cN+ rectal adenocarcinoma were retrieved from the European MRI and Rectal Cancer Surgery database. The prognostic role of the number of retrieved and examined nodes, nodal ratio, and log odds of positive lymph nodes (LODDS) was analyzed and compared by receiver operating characteristic curves, Pearson t…

AdultMaleCancer Researchmedicine.medical_specialtyMultivariate analysisColorectal cancerDisease-free survivalmedicine.medical_treatmentLODDSLocally advancedAdenocarcinomaDisease-Free SurvivalLog odds of positive lymph nodeRectal AdenocarcinomaMedicineHumansRectal cancerLog odds of positive lymph nodesNeoadjuvant therapyAgedNeoplasm StagingAged 80 and overReceiver operating characteristicddc:617business.industryRectal NeoplasmsHazard ratioGeneral MedicineNodal ratioChemoradiotherapyMiddle Agedmedicine.diseasePrognosisConfidence intervalNeoadjuvant TherapyOncologydisease-free survival; lodds; log odds of positive lymph nodes; neoadjuvant therapy; nodal ratio; rectal cancer; adenocarcinoma; adult; aged; aged 80 and over; disease-free survival; female; humans; lymph nodes; male; middle aged; neoplasm recurrence Local; Neoplasm Staging; Prognosis; Rectal Neoplasms; Chemoradiotherapy; Neoadjuvant TherapyNeoadjuvant therapyFemaleRadiologyLymph NodesNeoplasm Recurrence LocalbusinessAnticancer research
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Educational value of surgical videos on YouTube: quality assessment of laparoscopic appendectomy videos by senior surgeons vs. novice trainees

2019

Background To prepare for surgery, surgeons often recur to surgical videos, with YouTube being reported as the preferred source. This study aimed to compare the evaluation of three surgical trainees and three senior surgeons of the 25 most viewed laparoscopic appendectomy videos listed on YouTube. Additionally, we assessed the video conformity to the published guidelines on how to report laparoscopic surgery videos (LAP-VEGaS). Methods Based on the number of visualization, the 25 most viewed videos on laparoscopic appendectomy uploaded on YouTube between 2010 and 2018 were selected. Videos were evaluated on the surgical technical performance (GOALS score), critical view of safety (CVS), and…

Educational videos; Laparoscopic appendectomy; Resident surgeons; Surgical training; YouTube; Appendectomy; Health Education; Humans; Internet; Laparoscopy; Social Media; Surgical Procedures Operative; Video RecordingLaparoscopic surgerymedicine.medical_specialtyResident surgeonsmedicine.medical_treatmentSurgical training[SDV]Life Sciences [q-bio]Video Recordinglcsh:SurgeryEducational videoVideo qualityLikert scale03 medical and health sciences0302 clinical medicineCronbach's alphaLaparoscopic appendectomySurgical technicalAppendectomyHumansMedicineMedical physicsHealth EducationEducational videoseducational videos; laparoscopic appendectomy; resident surgeons; surgical training; youtube; appendectomy; health education; humans; internet; laparoscopy; social media; surgical procedures; operative; video recordingInternetSurgical ProceduresQuality assessmentbusiness.industryYouTubelcsh:Medical emergencies. Critical care. Intensive care. First aidlcsh:RD1-811lcsh:RC86-88.9Video imageOperative3. Good healthSettore MED/18 - Chirurgia GeneraleSurgical Procedures Operative030220 oncology & carcinogenesisEmergency MedicineHigh definitionLaparoscopy030211 gastroenterology & hepatologySurgeryResident surgeonbusinessSocial MediaResearch Article
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Impact of operation duration on postoperative outcomes of minimally-invasive right colectomy

2022

Aim: Operation time (OT) is a key operational factor influencing surgical outcomes. The present study aimed to analyse whether OT impacts on short-term outcomes of minimally-invasive right colectomies by assessing the role of surgical approach (robotic [RRC] or laparoscopic right colectomy [LRC]), and type of ileocolic anastomosis (i.e., intracorporal [IA] or extra-corporal anastomosis [EA]). Methods: This was a retrospective analysis of the Minimally-invasivE surgery for oncological Right ColectomY (MERCY) Study Group database, which included adult patients with nonmetastatic right colon adenocarcinoma operated on by oncological RRC or LRC between January 2014 and December 2020. Univariate…

right colectomyGastroenterologylaparoscopyrobotic right colectomyoperating timeminimally-invasive surgery
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Real-time fluorescence image-guided gastrointestinal oncologic surgery: Towards a new era

2021

Technological improvements are crucial in the evolution of surgery. Real-time fluorescence-guided surgery (FGS) has spread worldwide, mainly because of its usefulness during the intraoperative decision-making processes. The success of any gastrointestinal oncologic resection is based on the anatomical identification of the primary tumor and its regional lymph nodes. FGS allows also to evaluate the blood perfusion at the gastrointestinal stumps after colorectal or esophageal resections. Therefore, a reduction on the anastomotic leak rates has been postulated as one of the foreseeable benefits provided by the use of FGS in these procedures. Although the use of fluorescence in lymph node detec…

Splenic flexuremedicine.medical_specialtyColorectal cancerbusiness.industryEsophageal cancerSentinel lymph nodeGastroenterologyReviewEsophageal cancermedicine.diseaseColorectal cancerPrimary tumorFluorescenceImage-guided surgerymedicine.anatomical_structureBreast cancerOncologymedicineImage-guided surgeryAnastomotic leakSurgeryLymph nodeRadiologybusinessLymph nodeWorld Journal of Gastrointestinal Oncology
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Impact of conversion from laparoscopy to open surgery in patients with right colon cancer

2019

Conversion to open surgery is reported in up to 20 per cent of laparoscopic colectomies for cancer. This study aims to compare postoperative outcomes and survival between converted and successful laparoscopic right colectomy for cancer. Records of patients who underwent laparoscopic right colectomy for cancer between 2005 and 2015 were retrieved from the CLermontFerrand Ircad Mondor Hopital European Tours (CLIMHET) database. Perioperative, postoperative, and survival outcomes were evaluated. Multivariate analysis was performed to identify predictive factors for conversion. Overall, 445 patients underwent a successfully completed laparoscopic right colectomy and 28 (5.9%) were converted to …

MaleColectomiesmedicine.medical_specialtyColorectal cancermedicine.medical_treatmentOperative TimeDisease-Free SurvivalmedicineHumansLaparoscopySurvival rateColectomyColectomyconversion laparoscopy colon cancermedicine.diagnostic_testbusiness.industryCancerGeneral MedicinePerioperativemedicine.diseaseConversion to Open SurgerySurgerySurvival RateSettore MED/18 - Chirurgia GeneraleTreatment Outcomecolonic neoplasms; disease-free survival; female; humans; male; operative time; survival rate; treatment outcome; colectomy; conversion to open surgery;laparoscopyColonic NeoplasmsRight ColectomyFemaleLaparoscopybusiness
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Postoperative pain management in non-traumatic emergency general surgery: WSES-GAIS-SIAARTI-AAST guidelines

2022

Abstract Background Non-traumatic emergency general surgery involves a heterogeneous population that may present with several underlying diseases. Timeous emergency surgical treatment should be supplemented with high-quality perioperative care, ideally performed by multidisciplinary teams trained to identify and handle complex postoperative courses. Uncontrolled or poorly controlled acute postoperative pain may result in significant complications. While pain management after elective surgery has been standardized in perioperative pathways, the traditional perioperative treatment of patients undergoing emergency surgery is often a haphazard practice. The present recommended pain management g…

United StateAnalgesicsPain PostoperativePainAcuteUnited StatesPerioperative CareTreatmentEmergencyAbdomenEmergency MedicineHumansSurgeryAnalgesicAnesthesiaMorbidityHuman
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Robotic transanal total mesorectal excision: Is the future now?

2021

Total mesorectal excision (TME) is the standard surgical treatment for the curative radical resection of rectal cancers. Minimally invasive TME has been gaining ground favored by the continuous technological advancements. New procedures, such as transanal TME (TaTME), have been introduced to overcome some technical limitations, especially in low rectal tumors, obese patients, and/or narrow pelvis. The earliest TaTME reports showed promising results when compared with the conventional laparoscopic TME. However, recent publications raised concerns regarding the high rates of anastomotic leaks or local recurrences observed in national series. Robotic TaTME (R-TaTME) has been proposed as a nove…

High ratemedicine.medical_specialtyMinimally-invasive surgerybusiness.industryMinireviewsRoboticsRectal TumorsTransanal approachTotal mesorectal excisionSurgeryNatural orifice surgeryDissectionAnastomotic leaksmedicineNarrow pelvisRectal cancerSurgical treatmentRadical resectionbusinessTotal mesorectal excisionWorld Journal of Gastrointestinal Surgery
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Laparoscopic versus robotic right colectomy with extra-corporeal or intra-corporeal anastomosis: a systematic review and meta-analysis.

2020

Purpose: The aim of the present systematic review and meta-analysis is to compare laparoscopic right colectomy (LRC) versus robotic right colectomy (RRC) using homogeneous subgroup analyses for extra-corporeal anastomosis (EA) and intra-corporeal anastomosis (IA). Methods: MEDLINE, Scopus, and Web of Science databases were searched up to April 2020 for prospective or retrospective studies comparing LRC versus RRC on at least one short- or long-term outcome. The primary outcome was the length of hospital stay (LOS). The secondary outcomes included operative and pathological results, survival, and total costs. LRC and RRC were compared using three homogeneous subgroups: without distinction by…

medicine.medical_specialtyOperative TimeAnastomosisRobotic right colectomy03 medical and health sciences0302 clinical medicineRobotic Surgical ProceduresmedicineExtra-corporeal anastomosis; Intra-corporeal anastomosis; Laparoscopic right colectomy; Meta-analysis; Robotic right colectomyHumansIntra-corporeal anastomosisProspective StudiesColectomyRetrospective Studiesbusiness.industryAnastomosis SurgicalRetrospective cohort studyVascular surgeryLength of StayCardiac surgerySurgeryLaparoscopic right colectomyExtra-corporeal anastomosisMeta-analysisTreatment OutcomeCardiothoracic surgery030220 oncology & carcinogenesisMeta-analysisRight Colectomy030211 gastroenterology & hepatologySurgeryLaparoscopybusinessAbdominal surgeryLangenbeck's archives of surgery
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Milestones in robotic colorectal surgery development: an historical overview

2020

The present article is a historical review intended to trace the most important phases in the development of robotic surgical technology, with a special focus on colorectal surgery. The initial section considers the origin and some etymological aspects of the word “robot”. Then, a historical overview traces the development of robotic technology in industry and its implementation within the operating theatres. Finally, the first publications concerning robot-assisted colon and rectal surgery are reported together with a brief state of the art about this issue.

medicine.medical_specialtySettore MED/18 - Chirurgia Generalebusiness.industryGeneral surgerymedicineRobotic surgeryRobotic surgery colorectal surgery historybusinessColorectal surgery
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Predictors of surgical outcomes of minimally invasive right colectomy: the MERCY study

2022

PURPOSE: The optimal approach for minimally invasive (MIS) right colectomy remains under debate. This study aimed to describe surgical trends in the treatment of nonmetastatic right colon cancer and to identify predictors of short-term surgical outcomes. METHODS: A retrospective multicenter cohort study of Minimally-invasivE surgery for oncologic Right ColectomY (MERCY) was conducted on patients who underwent laparoscopic or robotic right colectomy between 2014 and 2020. Classification tree approach was used to describe the extracorporeal (EA) or intracorporeal (IA) anastomosis choice. Mixed-model regressions were used to identify patient- and surgery-related factors predictive of postopera…

Colonic NeoplasmAnastomosisAnastomosis SurgicalOperative TimeGastroenterologyRight colectomyIntracorporeal anastomosisRobotic surgeryIntracorporeal anastomosiColon cancerCohort StudiesTreatment OutcomeRobotic Surgical ProceduresRetrospective StudieMinimally invasive surgerySurgicalColonic NeoplasmsColon cancer; Intracorporeal anastomosis; Laparoscopy; Minimally invasive surgery; Right colectomy; Robotic surgery; Anastomosis Surgical; Cohort Studies; Colectomy; Humans; Operative Time; Retrospective Studies; Treatment Outcome; Colonic Neoplasms; Laparoscopy; Robotic Surgical ProceduresHumansLaparoscopyCohort StudieColectomyHumanRetrospective Studies
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Solitary splenic metastasis from nasopharyngeal carcinoma: a case report and systematic review of the literature

2016

Background: Solitary splenic metastases are a rare occurrence, and the nasopharyngeal carcinoma represents one of the most uncommon primary sources. The present study aimed to describe a rare case of a solitary single splenic metastasis from nasopharyngeal carcinoma and to assess the number of cases of isolated nasopharyngeal carcinoma metastases to the spleen reported in the literature. Main body: We describe the case of a 56-year-old man with a history of nasopharyngeal carcinoma and complete remission after chemo-radiotherapy. Three months after complete remission, positron emission tomography/ computed tomography scan revealed a hypermetabolic splenic lesion without increased metabolic …

MaleHerpesvirus 4 HumanPathologymedicine.medical_specialtySplenic metastasisBiopsymedicine.medical_treatmentSplenectomyNasopharyngeal neoplasmSplenic metastasis Nasopharyngeal carcinoma Systematic reviewSplenic NeoplasmReview03 medical and health sciencesRare Diseases0302 clinical medicineSurgical oncologyNasopharynxPositron Emission Tomography Computed TomographyBiopsymedicineCarcinomaHumansNeoadjuvant therapyNeoplasm StagingNasopharyngeal Carcinomamedicine.diagnostic_testbusiness.industrySplenic NeoplasmsCarcinomaNasopharyngeal NeoplasmsChemoradiotherapyMiddle Agedmedicine.diseaseMagnetic Resonance ImagingNeoadjuvant TherapySettore MED/18 - Chirurgia GeneraleTreatment OutcomeOncologyNasopharyngeal carcinomaLymphatic Metastasis030220 oncology & carcinogenesisSystematic reviewSplenectomyLaparoscopy030211 gastroenterology & hepatologySurgerybusinessWorld Journal of Surgical Oncology
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Additional file 1: of Educational value of surgical videos on YouTube: quality assessment of laparoscopic appendectomy videos by senior surgeons vs. …

2019

Table S1. Conformity to the 37 items of the LAP-VEGaS guidelines. (DOCX 172 kb)

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