0000000000137823

AUTHOR

Enrico Pace

showing 23 related works from this author

Cigarette smoke upregulates TLR4 expression and enhances TLR4 mediated responses

2006

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Cigaretta smoke up-regulates toll like receptor 4 (TLR4) expression and enhances TLR4 mediated responses

2005

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the expression of innate immunity and coagulative response in acute lung injury. septic verus non septic patients.

2007

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Elevated expression of prostaglandin receptor and increased release of prostaglandin E maintain the survival of CD45RO T cells in the inflamed human …

2007

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Counteracting effects of apigenin and leptin on lung adenocarcinoma cells.

2007

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Altered expression of TLR4 and beta 2 defensin in chronic obstructive pulmonary disease

2006

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Hypoallergenic fragment of Parj 2 increases functional expression of toll like receptor in atopic children

2006

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LTB4 is present in exudative pleural effusions and contributes actively to neutrophil recruitment in the inflamed pleural space

2004

SUMMARY The pleural space is a virtual compartment between the lung and chest wall that becomes filled with fluid and inflammatory cells during a variety of respiratory diseases. Here, we study the potential role of the eicosanoid metabolite leukotriene B4 (LTB4) in disparate diseases leading to acute (pneumonia) or chronic (tuberculosis, cancer) inflammation of the pleural space. LTB4 concentrations were significantly higher in pleural fluid due to pneumonia, tuberculosis and cancer with respect to congestive heart failure and correlated with neutrophil elastase, which is used as an indication of state of activation of neutrophils in the pleural space. Moreover, pleural LTB4 was biological…

LipopolysaccharidesPathologyHot TemperatureNeutrophilsLeukotriene B4Gene ExpressionEpitheliumchemistry.chemical_compoundNeoplasmsClinical StudiesImmunology and AllergyMedicineRespiratory systemPancreatic ElastasebiologyNeutrophilMiddle Agedrespiratory systemChemotaxis Leukocytemedicine.anatomical_structureNeutrophil InfiltrationNeutrophil elastaseLTB4Pleuralipids (amino acids peptides and proteins)medicine.symptomAdultmedicine.medical_specialtyImmunologyInflammationGranulocyteLeukotriene B4HumansRNA MessengerTuberculosis PulmonaryAgedArachidonate 5-LipoxygenaseLungbusiness.industryPneumoniaMacrophage Activationmedicine.diseaserespiratory tract diseasesPleural EffusionPneumoniaEicosanoidchemistryImmunologybiology.proteinbusinessClinical and Experimental Immunology
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Cigarette smoke up-regulates toll like receptor 4 (TLR4) expression and enhances TLR4 mediated responses

2005

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THE M3 MUSCARINIC RECEPTOR IS INVOLVED IN THE ACTIVATION OF AIRWAY EPITHELIUM IN VITRO

2006

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La risposta immune neella insufficienza respiratoria acuta in terapia intensiva: correlazione tra scores clinici e markers bioumorali

2006

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Alterated expression of leptin and its receptor in the epithelium of asthmatic patients

2006

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In vivo and in vitro effects of variants Parj2 in asthmatic children

2005

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Cigarette smoke increases TLR4 expression and modifies LPS mediated responses in airway epithelial cells.

2007

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Pleural mesothelial cells express both BLT2 and PPARa and mount an integrated response to pleural LTB4

2005

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Reduced apoptosis of CD8+ T-lymphocytes in the airways of mild COPD patients.

2008

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Multiple synergystic effects of fluticasone propionate and salmeterol on T lymphocyte activation in asthma

2004

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Lung Immune and Coagulative Host Response in Patients With Acute Exacerbations of Chronic Obstructive Pulmonary Disease (aeocpd).

2008

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Role of PGE2 in the invasiveness, growth and protection of cancer cells in malignant pleuritis

2006

Abstract The recurrence of pleural effusions is a common event in a variety of neoplastic diseases. The objective of this study was to identify the mechanisms promoting the homing and growth of cancer cells within the pleural space. A cancer cell line recovered from malignant pleural fluids (lung adenocarcinoma cell line) that constitutively expresses cyclooxygenase 2 (COX-2) and all types of prostaglandin receptors was studied. It was first demonstrated using a matrigel system, that malignant pleural fluids increase the invasiveness of adenocarcinoma cells more than congestive heart failure (CHF) pleural fluids. Moreover, exposure to exudative malignant, but not to CHF pleural fluids, incr…

Critical care medicine Acute lung injury Palliative medicine
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The expression of innate immunity and coagulative response in acute lung injury.Septic vs non sepstic patients.

2007

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Pleural LTB4 upregulates ICAM-1 molecules via STAT-1 activation on pleural mesothelial cells

2004

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The release of PGE2 by pleural macrophage prolongs the survival of T lymphocytee within the inflamed human pleural space

2005

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Leptin and Apigenin: Antagonists in the Apoptotic Pathway of Lung Adenocarcinoma Cell Line

2007

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