0000000000138081

AUTHOR

Stenroth L

showing 2 related works from this author

EMG-Assisted Muscle Force Driven Finite Element Model of the Knee Joint with Fibril-Reinforced Poroelastic Cartilages and Menisci.

2019

Abnormal mechanical loading is essential in the onset and progression of knee osteoarthritis. Combined musculoskeletal (MS) and finite element (FE) modeling is a typical method to estimate load distribution and tissue responses in the knee joint. However, earlier combined models mostly utilize static-optimization based MS models and muscle force driven FE models typically use elastic materials for soft tissues or analyze specific time points of gait. Therefore, here we develop an electromyography-assisted muscle force driven FE model with fibril-reinforced poro(visco)elastic cartilages and menisci to analyze knee joint loading during the stance phase of gait. Moreover, since ligament pre-st…

AdultCartilage ArticularMaleKnee JointTibiaElectromyographyFinite Element Analysismusculoskeletal systemModels BiologicalElasticityArticleMechanical engineeringBiomechanical PhenomenaHumansComputer SimulationMeniscusFemurStress MechanicalMuscle Skeletalhuman activitiesPorosityBiomedical engineeringScientific reports
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Association between osteocalcin and cognitive performance in healthy older adults.

2016

INTRODUCTION: cognitive deterioration and reductions of bone health coincide with increasing age. We examine the relationship between bone composition and plasma markers of bone remodelling with measures of cognitive performance in healthy adults.METHODS: this cross-sectional study included 225 old (52% women, mean age: 74.4 ± 3.3 years) and 134 young (52% women, mean age: 23.4 ± 2.7 years) adult participants from the MyoAge project. Whole body bone mineral density was measured by dual-energy X-ray absorptiometry. Blood analyses included a panel of bone-related peptides (dickkopf-1, osteoprotegerin, osteocalcin (OC), osteopontin, sclerostin, parathyroid hormone and fibroblast growth factor …

cognitionMaleAgingosteopontinvery elderlyCognitive declinesclerostinNeuropsychological Testsolder peopleExecutive FunctionAbsorptiometry PhotonBone Densityblood analysiscognitive defectphoton absorptiometry80 and overcalcium blood leveldickkopf 1 protein25 hydroxyvitamin D; calcium; dickkopf 1 protein; fibroblast growth factor 23; osteocalcin; osteopontin; osteoprotegerin; parathyroid hormone; sclerostin; biological marker; osteocalcin adult; aged; Article; blood analysis; bone density; bone remodeling; calcium blood level; cognition; controlled study; cross-sectional study; dual energy X ray absorptiometry; episodic memory; executive function; female; human; male; neuropsychological test; priority journal; working memory; adolescent; age; aging; blood; clinical trial; cognitive aging; cognitive defect; comparative study; Europe; metabolic bone disease; multicenter study; photon absorptiometry; psychology; sex difference; short term memory; very elderly; young adult Absorptiometry Photon; Adolescent; Adult; Age Factors; Aged; Aged 80 and over; Aging; Biomarkers; Bone Density; Bone Diseases Metabolic; Bone Remodeling; Cognition; Cognition Disorders; Cognitive Aging; Cross-Sectional Studies; Europe; Executive Function; Female; Humans; Male; Memory Episodic; Memory Short-Term; Neuropsychological Tests; Osteocalcin; Sex Factors; Young Adult; Ageing; Cognitive decline; Older people; Osteocalcincomparative studyAged 80 and overdual energy X ray absorptiometryadultAge Factorsclinical trialepisodic memorybiological markerPhotonEuropeagedMemory Short-Termfemalepriority journalyoung adultmetabolic bone diseaseBone RemodelingBone DiseasesEpisodicResearch PaperAdolescentMemory Episodicsex differenceOsteocalcinosteocalcinpsychologyArticleworking memoryfibroblast growth factor 23short term memorySex FactorsbloodMemoryparathyroid hormonecross-sectional studyHumanscontrolled studyhumanAbsorptiometrycalciumcognitive agingcognitive declineBone Diseases MetabolicAgeingikääntyminen25 hydroxyvitamin Dmulticenter studyCross-Sectional StudiesageShort-Termosteoprotegerinneuropsychological testMetabolicOlder peopleCognition DisordersBiomarkers
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