0000000000138437
AUTHOR
Mc Onorati
An RNA Memory Mechanism to Inherit Epigenetic Marks
Functional Interaction between the Nucleosome Remodeling Factor ISWI and the Hsrω non-coding RNA
The Nucleosome Remodeling Factor ISWI Functionally Interacts with the Hsr-ω non-coding RNA
Chromatin associated RNAi components take part in active transcriptional regulation in Drosophila
Emerging Roles for hnRNPs in post-transcriptional regulation: what can we learn from flies?
Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a highly conserved family of RNA-binding proteins able to associate with nascent RNAs in order to support their localization, maturation and translation. Research over this last decade has remarked the importance of gene regulatory processes at post-transcriptional level, highlighting the emerging roles of hnRNPs in several essential biological events. Indeed, hnRNPs are key factors in regulating gene expression, thus, having a number of roles in many biological pathways. Moreover, failure of the activities catalysed by hnRNPs affects various biological processes and may underlie several human diseases including cancer, diabetes and neur…