0000000000138864

AUTHOR

Raffaella Morreale Bubella

showing 58 related works from this author

THE CLINICAL ACTIVITY SCORE IN MANAGEMENT OF GRAVES’ OPHTHALMOPATHY: CORRELATION WITH ORBITAL MR IMAGING.

2015

Our aime was to investigate the correlation between GO ocular parameters obtained by MRI with contrast administration and the well-know clinical indicators of GO and to examine the relationship between the clinical course of hyperthyroidism and GO severity

GRAVES’ OPHTHALMOPATHY
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Lacrimal glands herniation in patients with Graves’ Ophthalmopathy: an effective MRI-derived marker of disease activity

2017

Aims and objectives Methods and materials Results Conclusion Personal information References

InflammationHead and neckStaginggenetic structuresEndocrine disordersEyesMREyes Head and neck MR Diagnostic procedure Staging Endocrine disorders InflammationDiagnostic procedure
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Adénocarcinome de la glande lacrymale dans un rétinoblastome bilatéral traité avec radiothérapie externe : à propos d’un cas

2011

This clinical case report describes the clinical findings and diagnosis of lacrimal gland adenocarcinoma that developed 20 years after external beam radiotherapy in the treatment of bilateral retinoblastoma. Visual acuity, slit lamp biomicroscopy, fundus color photography, nuclear magnetic resonance, lateral orbitotomy and histological analysis are described.

Visual acuityRadiotherapygenetic structuresLacrimal Gland AdenocarcinomaSettore MED/30 - Malattie Apparato Visivobusiness.industrymedicine.medical_treatmentFundus (eye)eye diseasesRadiation therapyBilateral retinoblastomaOphthalmologyLateral orbitotomyAdenocarcinoma of the lacrimal gland; Radiotherapy; Bilateral retinoblastomaAdenocarcinoma of the lacrimal glandmedicinesense organsExternal beam radiotherapyBilateral retinoblastomaSlit lamp biomicroscopymedicine.symptombusinessNuclear medicineJournal Français d'Ophtalmologie
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Lacrimal gland herniation in Graves ophthalmopathy: a simple and useful MRI biomarker of disease activity

2019

Lacrimal gland (LG) involvement in patients with Graves ophthalmopathy (GO) has been considered as a potential cause of the associated GO symptoms and different studies demonstrated the LG involvement in patients with GO than healthy controls. The aim of this study was to evaluate LG involvement, through measurement of its herniation, using a magnetic resonance imaging (MRI) index, in patients with different GO activities. Thirty-two consecutive Caucasian patients affected by GO were enrolled and grouped in group A (16 with inactive GO, CAS < 3) and B (16 with active GO, CAS ≥ 3) according to their GO activity. All patients underwent clinical-endocrinological assessment, a complete ocular e…

AdultMalemedicine.medical_specialtyHerniaTrabLacrimal glandSeverity of Illness IndexGastroenterologySettore MED/13 - Endocrinologia030218 nuclear medicine & medical imagingGraves' ophthalmopathy03 medical and health sciencesMagnetic resonance imaging0302 clinical medicineInternal medicineHumansMedicineRadiology Nuclear Medicine and imagingStage (cooking)Lacrimal apparatuAgedmedicine.diagnostic_testSettore MED/30 - Malattie Apparato Visivobusiness.industryThyroidLacrimal ApparatusSettore MED/37 - NeuroradiologiaOrbital diseasesMagnetic resonance imagingGeneral MedicineMiddle AgedGraves ophthalmopathymedicine.diseasemedicine.anatomical_structure030220 oncology & carcinogenesisBiomarker (medicine)FemaleRadiologySettore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessHormoneEuropean Radiology
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Variazione della pressione intraoculare durante le procedure diagnostiche endoscopiche

2012

Obiettivo. Obiettivo del presente studio è stato quello di rilevare qualsiasi possibile variazione nella pressione intraoculare (PIO) in soggetti non glaucomatosi sottoposti a esami endoscopici come la gastroscopia o la colonscopia, al fine di valutare il ruolo della tensione mentale in tali cambiamenti. Metodi. La frequenza cardiaca e il tono oculare sono stati misurati prima e subito dopo le procedure endoscopiche e 30’ dopo la somministrazione di un antagonista delle benzodiazepine in 100 soggetti, 52 uomini e 48 donne, sottoposti a gastroscopia, colonscopia o entrambi gli esami nella stessa occasione. Risultati. La frequenza cardiaca è diminuita da 82,10±14,41 a 76,11±10,96 30’ dopo la …

Settore MED/18 - Chirurgia GeneraleIntraocular pressureendoscopyvarations
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Large diurnal variation of intraocular pressure in open angle glaucoma in subjects with type A behaviour pattern

2014

Aim : To evaluate the possible causes of the greater perimetric damage found in OAG subjects with type A behaviour and the possible role of psycho-physiological stress. Materials and methods : 80 patients with OAG, 44 women and 36 men, 40 with type A behaviour and 40 with type B studied with the Type A/B Personality Questionnaire (A modified version of the Jenkins Activity Survey), underwent a complete ophthalmologic examination consisting of bio-microscopy, tonometry and daily tonometric curve, examination of the visual field by means of Octopus 1-2-3 computerised perimeter and its assessment with the Glaucoma Staging System 2 (GSS2), morphological monitoring of the Retinal Nerve Fibre Lay…

Intraocular pressuremedicine.medical_specialtyOpen angle glaucomabusiness.industrySettore MED/30 - Malattie Apparato VisivoeducationDiurnal temperature variationType A behaviour patternhumanitiesStress (mechanics)Blood pressureOphthalmologyType a behaviour pattern open angle glaucoma intraocular pressure perimetric damage arterial pressureOptometryMedicinebusiness
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Type A Behavior Pattern

2012

Aim : To evaluate the presence of type A behavior in patients affected by open-angle glaucoma (OAG) and the possible role of psychophysiological stress as a risk factor for OAG. Materials and methods Fifty patients, 30 women and 20 men, affected by OAG, underwent ophthalmological examination consisting of complete biomicroscopy, tonometry and daily tonometric curve, examination of the visual field by means of computerized perimeter "Octopus 1-2-3," and its assessment with the Glaucoma Staging System 2, morphologic monitoring of the retinal nerve fiber layer with GDx VCC and psychological assessment (Hamilton Anxiety Rating Scale) to evaluate the presence of anxiety and its level; type A/B p…

AdultMalemedicine.medical_specialtyIntraocular pressureOpen angle glaucomaHamilton Anxiety Rating ScaleType A Behavior Patternmedia_common.quotation_subjectGlaucomaManifest Anxiety ScaleTonometry OcularRisk FactorsOphthalmologyHumansMedicinePersonalityPsychological testingIntraocular PressureAgedmedia_commonSettore MED/30 - Malattie Apparato Visivobusiness.industryType A PersonalityType A and Type B personality theoryMiddle Agedmedicine.diseaseOpen-Angle Chronic GlaucomaOphthalmologyquality of lifeChronic DiseaseVisual Field TestsAnxietyFemaleVisual Fieldsmedicine.symptombusinessGlaucoma Open-AngleStress PsychologicalJournal of Glaucoma
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Risonanza magnetica DWI nei pazienti affetti da Orbitopatia di Graves.

2015

Orbitopatia di GravesSettore MED/30 - Malattie Apparato VisivoRisonanza magnetica DWI
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Azione antalgica di Hydrogel nell'orbitopatia basedowiana

2008

Hydrogel oftalmopatia basedowiana morbo di Graves
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La valutazione retinica mediante Tomografia a Coerenza Ottica (OCT) nel diabete mellito tipo 1.

2008

OCT diabete tipo 1
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Il film lacrimale:dall'anatomia alla semeiotica

2013

film lacrimaleghiandole lacrimalisindrome dell'occhio secco
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Su un caso di sindrome di Wolfram

2011

To aim of this paper was to offer a further contribution to the knowledge af the Wolfram Syndrome within the Italian population about hypotheses of its genetic trasmission and diagnostic problems.The study comprised the genetic investigation and the clinical ophthalmological examination of all the family members. Genetic investigation of family members showed the presence of a genetic disorder,consisting in a mutation of the gene wfs1, located on the short arm of chromosome 4, and which codifies for the protein Wolfranin. The gene wfs1 presents high penetrance and expression,since the mutation is recessive, it can only be clinicallly detected when it is present in the homozygous form. It sh…

Wolfram syndromeSettore MED/30 - Malattie Apparato Visivooptic atrophyGenetic diseases imborn
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L'occhio nella patologia endocrina

2014

oculopatieSettore MED/30 - Malattie Apparato VisivoMalattie endocrineretinopatia diabetica
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Evolution de le gliome du nerf optique chez des patients atteints de neurofibromatose de type I: environ 3 cas

2012

Settore MED/30 - Malattie Apparato Visivogliome nerf optiqueneurofibromatose de type I
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Valutazione tonometrica in due posizioni di sguardo nell'orbitopatia di Graves

2006

Aim.To asses effective role of thickness of superior rectus muscle in the variation of intraocular pression (IOP) in the patients with Graves' ophthalmopathy.Methods.IOP was measured in 76 eyes of 38 patients(mean age,42.4 years;range 19 to 58 years)with Graves' ophthalmopathy in primary and in upgaze position(Elevation with divergence of 23°).Results.IOP in 52 of the 76 eyes was 17.5 +/-2.12 mm Hgin primary position and 21.2 +/-2.75 mm Hg in upgaze position.In the eyes (28)with thickness of the superior rectus muscle >4.6 mm,IOP was 22.7+/-1.48 mm Hg in primary position and 27.1 +/-1.92 mm Hg in upgaze position.The difference in the values in this group is statistically significant ( the p…

Graves'ophthalmopathySuperior rectus muscleintraocular pressure
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Visual Field defects, type A personality,anxiety and coping style in patients with primary open angle glaucoma.

2012

Classification of glaucomatous visual field defects for different severity levels is important. The reasons for this are numerous, and include: to distinguish between healthy and diseased individuals, to have homogeneous grouping criteria when perimetry is used to define the severity of glaucoma, to adjust therapy on the basis of disease severity, to describe visual field conditions in a short and simple format, to monitor the progression of the disease, and to provide a common language for both clinical and research purposes. Many severity classification methods have been proposed, although none have had widespread use in clinical practice. Other methods, like the cumulative defect curve (…

Visual field defects type A personality primary open angle glaucoma.
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DISCOMFORT OCULARE E QUALITA’DELLA VITA NELLA TERAPIA CRONICA ANTIGLAUCOMATOSA: EFFETTO DI UNA SOLUZIONE OFTALMICA MONODOSE

2013

Glaucoma cronico ad angolo aperto qualità della vita discomfort oculare
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Lesioni perimetriche nelle neuriti ottiche

2004

Lesioni perimetricheneuriti ottiche perimetro Humphrey
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Involvement of the visual evoked potentials in type 2 diabetes

2013

Objective :To assess the function of the optic pathway in type 2 diabetics without retinopathy (40 subjects) or with mild Non Proliferative Diabetic Retinopathy (40 subjects). Methods: VEPs , elicited by means of pattern-reversal stimulation, were studied in a group of 80 non-insulin-dependent diabetics . Results: In subjects suffering from diabetes for less than 10 years, with mild retinopathy or without retinopathy, the amplitude N75-P100 decreased, and this is statistically significant with stimulation at 15’. As the time from disease onset increases, VEP latency (P100) shows a greater increase with the use of small checks (15’), than with large checks (30’) and this becomes statisticall…

Visual evoked potentials optic pathway conduction type 2 diabetes diabetic neuropathy.
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Traitement séquential avec des corticostéroides dans les ophtalmopathy Graves

2012

CorticostéroidesOphtalmopathy GravesSettore MED/30 - Malattie Apparato Visivo
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Visual field defects,type A personality,anxiety and coping styles in patients with primary open angle Glaucoma

2012

Settore MED/30 - Malattie Apparato VisivoVisual field defects type A personalityanxiety coping style primary open angle Glaucoma
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Complications ophthalmologiques au cours d'un diagnostic tardif de granulomatose de Wegener.

2008

Granulomatose de Wegener
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Case report di emangioma iuxtapapillare sporadico

2011

Emangioma iuxtapapillare von Hippel-Lindau
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Il campo visivo nei soggetti con comportamento di tipo A con glaucoma cronico ad angolo aperto

2011

Obiettivo: Valutare il campo visivo nei soggetti con GCAA di tipo A rispetto a quelli di tipo B Materiali e Metodi : Sono stati studiati 50 pazienti affetti da GCAA senza differenze significative di durata della malattia, dei quali 30 donne e 20 uomini,afferenti all’ambulatorio per il Glaucoma dell’Istituto di Oftalmologia dell’Università degli Studi di Palermo. Sono stati inclusi solo pazienti affetti da lesioni localizzate del campo visivo secondo la stadiazione del danno perimetrico del Glaucoma Staging System 2 (GSS2). L’età media è stata di 63,42 ± 12.9 senza significative differenze tra i due sessi. I pazienti sono stati sottoposti a: 1. Esame biomicroscopico completo 2. Tonometria e …

Settore MED/30 - Malattie Apparato VisivoAnsia Campo visivo Comportamento di tipo AGlaucoma cronico ad angolo apertoTonometria
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Ansia e comportamento di tipo A nei soggetti con Glaucoma cronico ad angolo aperto

2012

Ansia comportamento di tipo A Glaucoma cronico ad angolo apertoSettore MED/30 - Malattie Apparato Visivo
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Azione antalgica di Hydrogel nell'orbitopatia basedowiana

2007

La terapia dell'orbitopatia,nella fase acuta,si basa oltre che sulla correzione della turba endocrinologica,sulla protezione della cornea e sull'uso dei corticosteroidi ad alto dosaggio o di farmaci immunosoppressori o, in alternativa,sulla radioterapia orbitaria.Per attenuare la sintomatologia dolorosa,frequente nella fase acuta e che può inficiare la qualità della vita,data la componente flogistica,abbiamo voluto valutare gli effetti di una terapia antalgica mediante appliocazione sulla superficie palpebrale di un gel chirurgico criogenico decongestinante ( a contenuto di estratto di ananas più acido betaglicirretico),ad oggi utilizzato con risultati soddisfacenti in soggetti sottoposti a…

Settore MED/30 - Malattie Apparato VisivoOrbitopatia basedowiana (OB)American Thyroid Association MMI Hydrogel
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Antagonisti degli effetti collaterali delle prostaglandine

2013

Prostaglandine Glaucoma cronico ad angolo aperto Acido ialuronico
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Considerazioni su un caso di nistagmo familiare essenziale.

2007

A comparatively rare case of familial nystagmus is reported in a girl whose family tree was studied and the interest of which, apart from the need for greater involvement of health personnel and of school staff in campaigns for prevention of sight disturbances in infancy, was mainly related to the particular recessive trasmission bound to chromosome X with incomplete penetrance. The multiplicity of hereditary trasmission, in fact, explains the relative capricious expressivity of this pathological condition which should be born in mild in the event of genetic consultancy.

Settore MED/30 - Malattie Apparato VisivoNystagmusgenetics quality of life.
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Ansia,stili di coping e danno campimetrico in pazienti con Glaucoma cronico ad angolo aperto

2011

Settore MED/30 - Malattie Apparato VisivoGlaucoma cronico ad angolo aperto ansiastili di coping campo visivo
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Tossina botulinica e Neuropatia Ottica

2012

Tossina Botulinica Campo visivo Tomografia a coerenza ottica Neuropatia ottica
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Aberrations cornéennes pre et post intervention de la cataract avec incision supérieure de 2,8 mm en cornée claire.

2009

Cataract aberrations cornéennes.
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Parassiti: chi sono?

2012

Parassiti patogenesi delle parassitosi immunologia delle parassitosiSettore MED/30 - Malattie Apparato Visivo
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E' lo stress fattore di rischio per il glaucoma primario ad angolo aperto?

2011

Ansia Campo visivo Glaucoma cronico ad angolo apertoGDx VVC Stress
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Neuroprotezione del paziente con glaucoma cronico ad angolo aperto:ruolo della Citicolina in soluzione orale

2011

Aim: To verify the efficacy of Citicoline, taken orally, in the prevention of neurological damage in patients with Chronic Open Angle Glaucoma (COA G). Methods: 30 subjects with COA G were divided into 2 groups: 18 subjects (CT group) were treated with Citicoline and 12 (PP group) were treated with placebo. Both groups underwent 3 cycles of treatment. A cycle lasted 60 days and after every cycle there was a wash-out period of 30 days. On day 0, 60, 90, 150, 180, 240 and 270 all subjects underwent an examination of the optic nerve fibres by GDx VVC and a simultaneous recording of pattern reversal VEP s and pattern ER G. Results: In both groups endocular pressure values kept steady below 21 m…

Settore MED/30 - Malattie Apparato VisivoGlaucomaCiticolinaNeuroprotection
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Studio clinico randomizzato e controllato sull'efficacia clinica dell'uso di lenti multifocali refrattive versus diffrattive nella chirurgia della ca…

2006

IOL multifocali IOL diffrattive
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L'ansia nella chirurgia della cataratta

2009

Ansia Cataratta senile Facoemulsione
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Valutazione del tono oculare in diverse posizioni di sguardo nella oftalmopatia di Graves-Basedow

2003

tono oculareoftalmopatia di Graves-Basedow
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Effetti di una terapia con glucocorticoidi ev ad alte dosi sull'oftalmopatia di Graves moderata-severa:uno studio caso-controllo

2014

Oftalmopatia di Graveglucorticoidiesoftalmo
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Terapia sequenziale con corticosteroidi nell’Oftalmopatia di Graves

2012

Morbo di GraveOftalmopatia TiroideaTerapia steroidea
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La diplopia : studio epidemiologico nel quinquennio 2009-2013

2014

Diplopia epidemiologia test di Hess-Lancaster
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Anomalie oculari nella Sindrome di Down : risultati di uno studio retrospettivo

2015

Settore MED/30 - Malattie Apparato VisivoANOMALIE OCULARISINDROME DI DOWN
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Il Campo visivo nei soggetti di tipo A con Glaucoma cronico ad angolo aperto

2011

stressGlaucoma cronico ad angolo apertocampo visivo
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Tono oculare espessore oculare

2004

Tono oculare spessore corneale pachimetria corneale Glaucoma cronico ad angolo aperto
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Evaluation of the anti-inflammatory and analgesic action of hydrogel in thyroid orbitopathy.

2011

Purpose: To evaluate the analgesic efficacy of applying on the eyelid surface sterile hydrogel dressings containing substances such as pineapple extract which has anti-inflammatory and antioedema properties, and 18 beta-glycyrrhetinic acid. Design: Randomized prospective clinical trial. Methods: 50 patients (16 males and 34 females) affected with thyroid-associated orbitopathy in acute phase equally distributed in two groups. The level of patient satisfaction of the treatment was measured by answering a questionnaire before and after the treatment phase. Results: While 24 patients of study group reported an reduction in the pain only 2 of control group did. In the study group questionnaire’…

Settore MED/30 - Malattie Apparato VisivoThyroid orbitopathyhydrogelAnalgesic action anti-inflammatory action
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Disturbi emozionali nel trattamento chirurgico della cataratta

2010

Aim.The aim of this study was to appraise the degree of phychic uneasiness and anxiety in subjects who undergo surgical intervention of the cataract and the degree of satisfaction for the result of the interventetion.Methods.A sample of 50 subjects(22 males and 28 females)has been evaluated before the intervention on the cataract: the level of anxiety was measured by means of the Hamilton Anxiety Rating Scales T(HARS) and the degree of psychic uneasiness and psychopathological (phobia,somatization,depression) demonstrations by means of the test of psychic uneasiness-questionnaire IGD.The evalution of the degree of satisfaction for the results of the intervention has been obtained by means o…

Quality of lifeAnxiety.Cataract
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Terapia dell'occhio secco

2014

Dry eye syndrome lacrime artificiali iperosmolarità
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Epidemiologia delle otticopatie nelle urgenze oculistiche

2003

Otticopatieurgenze oculistiche
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Chirurgia della cataratta ad approccio refrattivo:"LRI",microincisione e "prelex"

2004

Cataratta LRI e prelex
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Paisseur centrale de la cornée chez le patients atteints d’acromégalie

2011

Settore MED/30 - Malattie Apparato VisivoCornée Acromégalie.
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Forskolin:valutazione efficacia ipotensiva nei pazienti in terapia massimale

2008

Glaucoma cronico ad angolo apertoForskolin
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The administration of a single dose collyrium containing hyaluronic acid, amino acids and echinacea purpurea improves the quality-of-life parameters …

2014

ophthalmic solutions Hyaluronic acid open-angle Glaucoma
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Corneal aberrations pre and post-application of new contact lens in the astigmatism after penetrating keratoplasty.

2007

Corneal aberrations new contact lens keratoplasty.
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Raffronto tra due formulazioni farmaceutiche di Timololo nel trattamento del glaucoma ad angolo aperto

2010

Settore MED/30 - Malattie Apparato VisivoGlaucoma cronico ad andolo aperto Timololo Compliance
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Central Corneal Thickness in patients with acromegaly

2011

Introduction Acromegaly is hormonal disorder caused by excessive growth hormone (GH) by the pituitary gland, this results in anatomical changes in many organs and also in the eye and specially in cornea. Objective To perform a connection between the disease activity and the corneal changes Matériels et Méthodes In 28 patients with acromegaly and in 22 voluntary healthy the central corneal thickness (CCT) was measured by pachymeter. And the patients were divided in 2 groups: the first (“group A”) contains 13 cases with not controlled acromegaly; and the other one (“group B”) is related to 15 patients with controlled acromegaly Résultats Patients with acromegaly have a central corneal thickne…

Settore MED/30 - Malattie Apparato Visivocorneal thickness acromegaly GH
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Photocoagulation laser et bevacizumab intravitréen dans la télengectasie rétinienne idiopatique:à propos d'un cas.

2008

Bevacizumab intravitréen Télengectasie rétinienne idiopatique
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Laser e Dry Eye syndrome

2014

Laser Dry Eye Syndrome Lasik e laser ad eccimeri acido ialuronico
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PaTOLOGIE OCULOPALPEBRALI SINDERMATOTICHE

2013

patologia palpebraleblefarocalasiblefaroptosi
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Spontaneous post-partum regression of diabetic macular edema:OCT3 analysis.

2007

Diabetic macular edema OCT3 pregnancy.
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