0000000000139421

AUTHOR

Manuel Desco

0000-0003-0989-3231

showing 2 related works from this author

Diez años de investigación traslacional colaborativa en enfermedades mentales: el CIBERSAM

2019

Psychiatry and Mental healthbusiness.industryMedicinebusinessHumanitiesRevista de Psiquiatría y Salud Mental
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Age at First Episode Modulates Diagnosis-Related Structural Brain Abnormalities in Psychosis.

2016

Brain volume and thickness abnormalities have been reported in first-episode psychosis (FEP). However, it is unclear if and how they are modulated by brain developmental stage (and, therefore, by age at FEP as a proxy). This is a multicenter cross-sectional case-control brain magnetic resonance imaging (MRI) study. Patients with FEP (n = 196), 65.3% males, with a wide age at FEP span (12-35 y), and healthy controls (HC) (n = 157), matched for age, sex, and handedness, were scanned at 6 sites. Gray matter volume and thickness measurements were generated for several brain regions using FreeSurfer software. The nonlinear relationship between age at scan (a proxy for age at FEP in patients) and…

Cingulate cortexAdultMalemedicine.medical_specialtyAdolescentBipolar disorderCortical thicknessTemporal lobe03 medical and health sciencesYoung Adult0302 clinical medicineInternal medicinemedicineHumansAge of OnsetGray MatterChildTemporal cortexFirst episodeCerebral CortexParietal lobeAge FactorsAge at onsetRegular ArticleCortical volumeFirst-episode psychosisMagnetic Resonance Imaging030227 psychiatryPsychiatry and Mental healthCross-Sectional StudiesFrontal lobePsychotic DisordersCase-Control StudiesBrain sizeCardiologySchizophreniaFemaleAge of onsetPsychologyNeuroscience030217 neurology & neurosurgeryMRISchizophrenia bulletin
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