0000000000140975
AUTHOR
Sacco R.
Estimation of lead-time bias and its impact on the outcome of surveillance for the early diagnosis of hepatocellular carcinoma.
Lead-time is the time by which diagnosis is anticipated by screening/surveillance with respect to the symptomatic detection of a disease. Any screening program, including surveillance for hepatocellular carcinoma (HCC), is subject to lead-time bias. Data regarding lead-time for HCC are lacking. Aims of the present study were to calculate lead-time and to assess its impact on the benefit obtainable from the surveillance of cirrhotic patients. Background & Aims: Lead-time is the time by which diagnosis is anticipated by screening/surveillance with respect to the symptomatic detection of a disease. Any screening program, including surveillance for hepatocellular carcinoma (HCC), is subject to …
An international assessment of the adoption of enhanced recovery after surgery (ERAS®) principles across colorectal units in 2019–2020
Aim The Enhanced Recovery After Surgery (ERAS® ) Society guidelines aim to standardise perioperative care in colorectal surgery via 25 principles. We aimed to assess the variation in uptake of these principles across an international network of colorectal units. Method An online survey was circulated amongst European Society of Coloproctology members in 2019/20. For each ERAS® principle, respondents were asked to score how frequently the principle was implemented in their hospital, from 1 ('rarely') to 4 ('always'). Respondents were also asked to recall whether practice had changed since 2017. Subgroup analyses based on hospital characteristics were conducted. Results Of hospitals approache…
Search for di-muon decays of a low-mass Higgs boson in radiative decays of the Gamma(1S)
We search for di-muon decays of a low-mass Higgs boson (A(0)) produced in radiative Gamma(1S) decays. The Gamma(1S) sample is selected by tagging the pion pair in the Gamma(2S, 3S) -> pi(+)pi(-) Gamma(1S) transitions, using a data sample of 92.8 x 10(6) Gamma(2S) and 116.8 x 10(6) Gamma(3S) events collected by the BABAR detector. We find no evidence for A(0) production and set 90% confidence level upper limits on the product branching fraction B(Gamma(1S) -> gamma Lambda(0)) x B(Lambda(0)->mu(+)mu(-)) in the range of (0.28 - 9.7) x 10(-6) for 0.212 gamma Lambda(0), Lambda(0) -> mu(+)mu(-) to set limits on the effective coupling of the b quark to the Lambda(0).