0000000000141242

AUTHOR

Ping Song

showing 2 related works from this author

Inhibitory Effect of Kurarinone on Growth of Human Non-small Cell Lung Cancer: An Experimental Study Both in Vitro and in Vivo Studies

2018

Kurarinone, a flavonoid isolated from Sophora flavescens Aiton, has been reported to have significant antitumor activity. However, the cytotoxic activity of kurarinone against non-small cell lung cancer (NSCLC) cells is still under explored. In our study, we have evaluated the inhibitory effects of kurarinone on the growth of NSCLC both in vivo and in vitro as well as the molecular mechanisms underlying kurarinone-induced A549 cell apoptosis. The results showed that kurarinone effectively inhibited the proliferation of A549 cells with little toxic effects on human bronchial epithelial cell line BEAS-2B. FASC examination and Hoechst 33258 staining assay showed that kurarinone dose-dependentl…

0301 basic medicineCaspase 303 medical and health sciences0302 clinical medicineIn vivoCytotoxic T cellPharmacology (medical)Protein kinase BPharmacologyA549 cellCaspase-9biologyChemistrymulti-targetlcsh:RM1-950apoptosiskurarinoneIn vitrorespiratory tract diseases030104 developmental biologyanticancer activitylcsh:Therapeutics. PharmacologyApoptosis030220 oncology & carcinogenesisCancer researchbiology.proteinlung carcinomaFrontiers in Pharmacology
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Differences in Inhibitory Control between Impulsive and Premeditated Aggression in Juvenile Inmates

2017

Inhibitory control dysfunction was considered a universal characteristic of violent offenders. The aim of this study was to examine differences in inhibitory control between two subtypes of violent youth; those displaying predominantly impulsive and those presenting predominantly premeditated aggression (PM). Forty-four juvenile offenders, defined on the basis of the Procedures for the Classification of Aggressive/Violent Acts (Stanford and Barratt, 2001) participated (N = 23: impulsive; N = 21 premeditated). A visual Go/NoGo task was used to compare behavioral responses and event-related potentials (ERPs) between groups. The task contained two letters (W and M), W was the Go stimulus and M…

Poison controlStimulus (physiology)Impulsivityevent-related potentialslcsh:RC321-571Developmental psychology03 medical and health sciencesBehavioral Neuroscienceviolence0302 clinical medicineEvent-related potentialInjury preventionmental disordersmedicineJuvenile delinquencyJuvenile0501 psychology and cognitive scienceslcsh:Neurosciences. Biological psychiatry. NeuropsychiatryBiological PsychiatryOriginal ResearchAggression05 social sciencespremeditated aggressioninhibitory controlPsychiatry and Mental healthNeuropsychology and Physiological PsychologyNeurologyimpulsive aggressionmedicine.symptomPsychology030217 neurology & neurosurgerypsychological phenomena and processes050104 developmental & child psychologyNeuroscienceFrontiers in Human Neuroscience
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