0000000000144475

AUTHOR

Giovanni De Manzoni

showing 4 related works from this author

Extranodal Extension of Nodal Metastases Is a Poor Prognostic Indicator in Gastric Cancer: a Systematic Review and Meta-analysis.

2016

Introduction: The extranodal extension (ENE) of nodal metastases (the extension of neoplastic cells through the nodal capsule into the perinodal soft tissue) is a histological feature that has been considered a prognostic factor in several cancers, but the role in gastric cancer was not yet investigated. We aimed to investigate the prognostic role of ENE in patients affected by gastric cancer through a systematic review and meta-analysis. Material and Methods: Two independent authors searched major databases until 09/30/2015 to identify studies providing data on gastric cancer patients’ prognostic parameters and comparing patients with ENE (ENE+) vs intra-nodal extension (ENE−). The data we…

Oncologymedicine.medical_specialty03 medical and health sciencesNodal Metastases Extranodal Extension Gastric Cancer0302 clinical medicineextranodal extension nodal metastases gastric cancerRecurrenceStomach NeoplasmsInternal medicineExtranodal extensionmedicineOdds RatioHumansGastric cancer . ENE . Extranodal extensionENE; Extranodal extension; Gastric cancer; Lymph node metastasis; Surgery; GastroenterologyProportional Hazards ModelsLymph node metastasisbusiness.industryProportional hazards modelNodal MetastasesHazard ratioConfoundingGastroenterologyCancerOdds ratiomedicine.diseasePrognosisConfidence interval030220 oncology & carcinogenesisMeta-analysisRelative riskLymphatic MetastasisENE030211 gastroenterology & hepatologySurgeryLymph NodesNeoplasm Recurrence LocalbusinessGastric cancerJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
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Individualisierte Chirurgie des Magenkarzinoms

2013

Die chirurgische Behandlung beim Magenkarzinom besteht aus ablativen und rekonstruktiven Phasen. Die wesentlichen Phasen der Operation sind: 1. Ablosung des Omentum majus vom Querkolon und Eroffnung der Bursa omentalis, 2. Mobilisierung und Durchtrennung des Bulbus duodeni, 3. Mobilisierung des Magens entlang der grosen Kurvatur, 4. Mobilisierung des Magens entlang der kleinen Kurvatur, 5. Retrogastrale Mobilisierung und Durchtrennung der A. gastrica sinistra, 6. Durchtrennung des Magens bzw. Mobilisierung und Durchtrennung des Osophagus, 7. Lymphadenektomie (meist in Kombination mit anderen Schritten), 8. Rekonstruktion der Passage. Die Reihenfolge der Operationsschritte variiert in Abhang…

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The SIC-GIRCG 2013 Consensus Conference on Gastric Cancer.

2014

Abstract The topic chosen by the Board of the Italian Society of Surgery for the 2013 annual Consensus Conference was gastric cancer. With this purpose, under the direction of 2 chairmen, 36 experts nominated by the Regional Societies of Surgery and by the Italian Research Group for Gastric Cancer (GIRCG) participated in an experts consensus exercise, preceded by a questionnaire and mainly held by telematic vote, in accordance with the rules of the Delphi method. The results of this Consensus Conference, presented to the 115th National Congress of the Italian Society of Surgery, and approved in plenary session, are reported in the present paper.

Malemedicine.medical_specialtyGastric cancer Surgery Chemotherapy Staging Endoscopy LaparoscopyStagingDelphi TechniqueMEDLINEDelphi methodchemotherapyEndosonographyDelphi Technique; Endosonography; Female; Humans; Italy; Lymph Node Excision; Male; Neoplasm Staging; Societies Medical; Stomach NeoplasmsStomach NeoplasmStomach NeoplasmsMedicalmedicineHumanslapaoscopyguidelinesgastric cancer; chemotherapy; staging endoscopy; lapaoscopySocieties MedicalNeoplasm StagingSettore MED/06 - ONCOLOGIA MEDICAtreatmentbusiness.industryConsensus conferenceCancerEndoscopymedicine.diseasePlenary sessionSurgerySettore MED/18 - Chirurgia GeneraleGastric CancerItalyLymph Node ExcisionNeoplasm stagingLaparoscopySurgeryFemaleguidelines; Gastric Cancer; treatmentbusinessSocietiesstaging endoscopyHuman
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Extranodal extension of lymph node metastasis is a marker of poor prognosis in oesophageal cancer: A systematic review with meta-analysis

2016

The extranodal extension (ENE) of nodal metastasis is the extension of neoplastic cells through the nodal capsule into the perinodal adipose tissue. This histological feature has recently been indicated as an important prognostic factor in different types of malignancies; in this manuscript, we aim at defining its role in the prognosis of oesophageal cancer with the tool of meta-analysis. Two independent authors searched SCOPUS and PubMed until 31 August 2015 without language restrictions. The studies with available data about prognostic parameters in subjects with oesophageal cancer, comparing patients with the presence of ENE (ENE+) versus only intranodal extension (ENE-), were considered…

Poor prognosismedicine.medical_specialty2734OESOPHAGUSLymph node metastasisGastroenterologyCANCER; METASTASIS; OESOPHAGUS; 2734Pathology and Forensic MedicineMetastasis03 medical and health sciences0302 clinical medicineExtranodal extensionInternal medicinemedicinebusiness.industryExtranodal ExtensionConfoundingCancerCANCER; METASTASIS; OESOPHAGUSGeneral Medicinemedicine.diseaseCANCERSurgery030220 oncology & carcinogenesisMeta-analysisRelative riskMETASTASIS030211 gastroenterology & hepatologybusiness
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