0000000000147320

AUTHOR

Paul Tafforeau

showing 7 related works from this author

A multiscale X-ray phase-contrast tomography dataset of whole human left lung

2021

ABSTRACTTechnological advancements in X-ray imaging using bright and coherent synchrotron sources now allows to decouple sample size and resolution, while maintaining high sensitivity to the microstructure of soft, partially dehydrated tissues. The recently developed imaging technique, hierarchical phase-contrast tomography, is a comprehensive approach to address the challenge of organ-scale (up to tens of centimeters) soft tissue imaging with resolution and sensitivity down to the cellular level. Using this technique, we imaged ex vivo an entire human left lung at an isotropic voxel size of 25.08 μm along with local zooms down to 6.05 - 6.5 μm and 2.45 - 2.5 μm in voxel size. The high tiss…

MicrometreLeft lungPhase contrast tomographyMaterials sciencelawResolution (electron density)X-raySynchrotron radiationTomographySynchrotronlaw.inventionBiomedical engineering
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The bronchial circulation in COVID-19 pneumonia.

2021

American journal of respiratory and critical care medicine : AJRCCM 205(1), 121-125 (2022). doi:10.1164/rccm.202103-0594IM

Pulmonary and Respiratory Medicine2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)bronchial circulationRespiratory SystemCritical Care and Intensive Care Medicine03 medical and health sciences0302 clinical medicineMedicinepneumoniaIntussusceptive angiogenesis11 Medical and Health Sciencesintussusceptive angiogenesisbusiness.industryCOVID-19Bronchial circulationhierarchial phase-contrast tomographymedicine.disease3. Good healthPneumonia030228 respiratory systemImmunologyHuman medicinebusiness030217 neurology & neurosurgery
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Multiscale three-dimensional imaging of intact human organs down to the cellular scale using hierarchical phase-contrast tomography

2021

ABSTRACTHuman organs are complex, three-dimensional and multiscale systems. Spatially mapping the human body down through its hierarchy, from entire organs to their individual functional units and specialised cells, is a major obstacle to fully understanding health and disease. To meet this challenge, we developed hierarchical phase-contrast tomography (HiP-CT), an X-ray phase propagation technique utilising the European Synchrotron Radiation Facility’s Extremely Brilliant Source: the world’s first high-energy 4th generation X-ray source. HiP-CT enabled three-dimensional and non-destructive imaging at near-micron resolution in soft tissues at one hundred thousand times the voxel size whilst…

Phase contrast tomographyHuman healthThree dimensional imagingCoronavirus disease 2019 (COVID-19)Human kidneyHuman bodyTomographyBiologyVoxel sizeBiomedical engineering
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Anthropoid versus strepsirhine status of the African Eocene primates Algeripithecus and Azibius: craniodental evidence.

2009

Recent fossil discoveries have demonstrated that Africa and Asia were epicentres for the origin and/or early diversification of the major living primate lineages, including both anthropoids (monkeys, apes and humans) and crown strepsirhine primates (lemurs, lorises and galagos). Competing hypotheses favouring either an African or Asian origin for anthropoids rank among the most hotly contested issues in paleoprimatology. The Afrocentric model for anthropoid origins rests heavily on the >45 Myr old fossil Algeripithecus minutus from Algeria, which is widely acknowledged to be one of the oldest known anthropoids. However, the phylogenetic position of Algeripithecus with respect to other p…

10207 Department of Anthropology010506 paleontologyAzibiusZoologyLemuractivity pattern1100 General Agricultural and Biological Sciences01 natural sciencesGeneral Biochemistry Genetics and Molecular Biology2300 General Environmental ScienceNocturnality03 medical and health sciencesSpecies Specificity1300 General Biochemistry Genetics and Molecular BiologyResearch articles2400 General Immunology and Microbiologybiology.animalAnimalsOdontometryPrimateCladePhylogenyprimate evolution030304 developmental biology0105 earth and related environmental sciencesGeneral Environmental Science[ SDU.STU.PG ] Sciences of the Universe [physics]/Earth Sciences/Paleontology0303 health sciencesGeneral Immunology and Microbiologybiology300 Social sciences sociology & anthropologyFossilsAlgeripithecus[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]StrepsirhiniHaplorhiniGeneral Medicinebiology.organism_classificationStrepsirhini[ SDV.BID.EVO ] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]toothcombed primatesToothcombAlgeriaAfricaGeneral Agricultural and Biological Sciences[SDU.STU.PG]Sciences of the Universe [physics]/Earth Sciences/PaleontologyTooth
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100‐million‐year‐old ant–conifer associates inside French amber: a fortuitous or ecological association?

2020

International audience; Ants exhibit a plethora of ecological interactions with terrestrial plants. These interactions are broadly surveyed in modern ecosystems, but are much more difficult to unveil in the fossil record. Here, we report a unique ant–conifer association preserved in an opaque piece of 100‐million‐year‐old amber from Charentes in Western France, revealed by propagation phase‐contrast X‐ray synchrotron microtomography (PPC‐SRμCT). Most legs of the ant encircle the conifer twig, and the arthropod harbours a hooked position onto the leafy axis. The conifer is assigned to Glenrosa carentonensis Moreau, Néraudeau, Tafforeau and Dépré, whereas the ant is ascribed to Gerontoformica…

0106 biological sciences0303 health sciencesbiologyEcologyAssociation (object-oriented programming)Paleontologybiology.organism_classification010603 evolutionary biology01 natural sciencesCretaceousANT03 medical and health sciencesSphecomyrminaeGeography[SDU.STU.PG]Sciences of the Universe [physics]/Earth Sciences/PaleontologyEcology Evolution Behavior and Systematics030304 developmental biology
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Early Triassic conodont clusters from South China: revision of the architecture of the 15 element apparatuses of the superfamily Gondolelloidea

2012

Several fused clusters of conodont elements of the genera Neospathodus and Novispathodus were recovered from limestone beds at the Dienerian-Smithian and Smithi- an-Spathian boundaries, respectively, from several localities in Guangxi province, South China. Conodont clusters are otherwise extremely rare in the Triassic, and these are first described for the Early Triassic. The exceptional specimens partially preserve the relative three-dimensional position and orientation of ramiform elements and are therefore extremely important for testing hypotheses on the architecture of appa- ratuses. These specimens partly confirm the previous recon- struction of the Novispathodus apparatus by Orchard…

010506 paleontologySouth chinaSubfamilybiologyEarly TriassicPaleontologySUPERFAMILY010502 geochemistry & geophysicsbiology.organism_classification01 natural sciencesPaleontology10. No inequalityConodontEcology Evolution Behavior and SystematicsGeology0105 earth and related environmental sciencesPalaeontology
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Synthèse sur la diversité des préservations végétales du site d’Archingeay-Les Nouillers (France) : un Konservat-Lagerstätte pour les flores de l’Alb…

2017

Since the end of the XXth century, the palaeontological site of Archingeay-Les Nouillers (Charente-Maritime, western France) continued to afford Albian-Cenomanian (ca 93–113 Ma) plant meso- and macroremains. The successive excavations provided numerous specimens useful for the reconstruction of mid-Cretaceous coastal forest ecosystems. However, one of the most remarkable features of this locality is the diversity of plant preservations. Unique in Europe from this point of view, the fossiliferous site of Archingeay-Les Nouillers yielded compressions with or without cuticle, impressions/imprints, and silicified permineralizations/petrifications. The quality of the silicified tissues and the c…

0106 biological sciences010506 paleontologyGeographyCuticleForest ecologyPaleontology15. Life on land010603 evolutionary biology01 natural sciencesArchaeology0105 earth and related environmental sciencesAnnales de Paléontologie
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