0000000000147497

AUTHOR

A Blettgen

showing 2 related works from this author

SEXUALHORMONE-BINDING GLOBULINE (SHBG) AND FREE TESTOSTERONE (FTE) IN PATIENTS WITH ULLRICH TURNLR SYNDROME(UTS) RECEIVING OXANDROLONE

1993

Our investigation showed that the concentration of SHBG decreased in healthy girls and boys at increased FIE concentrations. It was therefore the aim of the present study to examine the effects of anabolic steroid oxandrolone in SHBG and FTE concentrations in patients with Turner's syndrome. The normal dose to promote growth in patients wilh UTS is 0,1 mg/kg/BW. Our patients received a very low dose of 1,25 mg oxandrolone/doy. We analysed 21 sera of UTS patients. The determination of SHBG concentrations was performed with the IRMA (Famos diagnostics, Oulunsala, Finnland), the concentration of FTE was determined with the RIA (Immunchem.Corporation, Carson, USA). In 7 untreated UIS patients w…

medicine.medical_specialtyPubic hair stagebiologyFree testosteronebusiness.industrymedicine.medical_treatmentLow doseOxandroloneSex hormone-binding globulinEndocrinologyInternal medicinePediatrics Perinatology and Child Healthbiology.proteinMedicineIn patientbusinesshormones hormone substitutes and hormone antagonistsTestosteroneAnabolic steroidmedicine.drugPediatric Research
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MR IMAGING AND HORMONAL FINDINGS IN PATIENTS WITH IDIOPATHIC GROWTH HORMONU DEFICIENCY

1993

Until the introduction of MR imaging in neuroradiological diagnostic, diagnosis of the ecotopic posterior pituitary lobe, first described by the pathologist Priesel in 1920, was rare. Recently it has increasingly been diagnosed by MR in patients whose anamnesis showed birth trauma. We performed MR of the hypothalamic-pituitary region in 17 patients with idiopathic growth hormone deficiency. 8 patients had additional deficiencies of the anterior pituitary lobe whereas the function of the posterior lobe of the hypophysis was normal in all patients. Indications of birth trauma were present in only 2 patients. The cause of anterior lobe insufficiency was determined by MR in 8 patients with panh…

Pituitary stalkmedicine.medical_specialtybusiness.industryBirth traumaAnatomymedicine.diseaseHypoplasiaLobeInfundibulummedicine.anatomical_structureAnterior pituitaryPosterior pituitaryMedian eminencePediatrics Perinatology and Child HealthMedicineRadiologybusinessPediatric Research
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