0000000000148225

AUTHOR

Elisabeth Heylen

showing 2 related works from this author

Multiple reassortment and interspecies transmission events contribute to the diversity of feline, canine and feline/canine-like human group A rotavir…

2011

Abstract RNA–RNA hybridization assays and complete genome sequence analyses have shown that feline rotavirus (FRV) and canine rotavirus (CRV) strains display at least two distinct genotype constellations (genogroups), represented by the FRV strain RVA/Cat-tc/AUS/Cat97/1984/G3P[3] and the human rotavirus (HRV) strain RVA/Human-tc/JPN/AU-1/1982/G3P3[9], respectively. G3P[3] and G3P[9] strains have been detected sporadically in humans. The complete genomes of two CRV strains (RVA/Dog-tc/ITA/RV198-95/1995/G3P[3] and RVA/Dog-tc/ITA/RV52-96/1996/G3P[3]) and an unusual HRV strain (RVA/Human-tc/ITA/PA260-97/1997/G3P[3]) were determined to further elucidate the complex relationships among FRV, CRV a…

Microbiology (medical)RotavirusSettore MED/07 - Microbiologia E Microbiologia ClinicaGenes ViralGenotypevirusesReassortmentBiologymedicine.disease_causeCat DiseasesMicrobiologyGenomeRotavirus InfectionsFelineDogsReassortmentRotavirusZoonosesGenotypeGeneticsmedicineAnimalsHumansDog DiseasesMolecular BiologyEcology Evolution Behavior and SystematicsPhylogenyGeneticsWhole genome sequencingNSP1Phylogenetic treeStrain (biology)virus diseasesGenetic VariationSequence Analysis DNARotaviruVirologyInfectious DiseasesInterspecies transmissionChild PreschoolCatsReassortant VirusesHumanInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
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Evolution of DS-1-like human G2P[4] rotaviruses assessed by complete genome analyses

2013

Group A rotaviruses (RVAs) are a leading cause of viral gastroenteritis in children, with G2P[4] RVA being one of the most common human strain worldwide. The complete genome sequences of nine G2P[4] RVA strains, selected from a 26-year archival collection (1985-2011) established in Palermo/Italy, were determined. A strain associated with a peak of G2P[4] RVA activity in 1996 resembled a reassortant strain identified in Kenya in 1982 and completely differed in the genomic make up from more recent strains that circulated during 2004-2011. Conversely, the 2004-2011 G2P[4] RVAs were genetically more similar to contemporary RVA strains circulating globally. Recent G2P[4] strains possessed either…

RotavirusSettore MED/07 - Microbiologia E Microbiologia ClinicaMolecular Sequence DataReassortmentSequence alignmentGenome ViralBiologymedicine.disease_causeGenomeRotavirus InfectionsEvolution MolecularViral ProteinsPhylogeneticsVirologyRotavirusGenotypemedicineHumansAmino Acid SequencePeptide sequencePhylogenyGeneticsRotavirus G2P[4] evolution ItalyStrain (biology)VirologyItalySequence AlignmentJournal of General Virology
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