0000000000148230
AUTHOR
Emanuele Calabrò
Thermostabilization of BSA in TMAO Water Mixtures by Infrared Spectroscopy
Background:Trimethylamine-N-Oxide (TMAO) is a small organic molecule derived from the metabolism of L-carnitine and choline after ingestion of animal food. TMAO has many functions such as electron acceptor, an osmolyte, stabilizer of macromolecules folding. It seems that TMAO plays an important role in nature but, in humans, it is a remnant of the evolution of the osmolyte system.Objective:The present paper is addressed on the study of thermal stability of hydrated Bovine Serum Albumins (BSA) in the presence of water and TMAO water solution by means of InfraRed spectroscopy. In particular, this work has investigated the protein amide I spectral regions, which is sensitive to protein seconda…
Core and Shell: facciate storiche e nuovi edifici. Il caso dell’ex Chelsea and Fulham Power Station a Londra
The maintenance of the façade(s) is one of the most common solutions – in countries where this intervention is allowed – which can also guarantee the “preservation” of the existing built herit- age, as well as the construction of new “zero land consumption buildings”. The English term used to identify this area of work is Façadism. The paper analyses a perfect example attributable to this area of work that is being implement- ed on the former Chelsea and Fulham Power Station in London. The refurbishment project, in the construction phase, was instructed to Midgard Design Service Ltd (Design Department of the Irish construction company JRL Group Limited) which will transform the entire area …