In vivo morphological and clinical effects of a desensitizing agent

Objectives: This study evaluated the in vivo effectiveness of Universal Dentin Sealant (UDS), a new resin-based material, as dentinal desensitizing agent on dentin morphology and clinical symptoms. Materials and methods: Thirty premolars, exhibiting non-carious cervical lesions, and scheduled for extraction for periodontal reasons, were selected for the ultrastructural study. These samples were randomly divided into three groups ( n = 10): group 1, brushing with UDS; group 2, brushing with Flor-Opal ® Varnish (FOV); and group 3, untreated control. After 7 days, teeth were extracted and samples processed for SEM and TEM comparative observations. The in vivo study was carried out on 90 teeth …