0000000000154379

AUTHOR

Markus K. Diener

showing 2 related works from this author

Repeated resection for recurrent intrahepatic cholangiocarcinoma: A retrospective German multicentre study.

2020

Background Tumour recurrence is common after resection of intrahepatic cholangiocarcinoma (ICC). Repeated resection is a potential curative treatment, but outcomes are not well-defined thus far. The aim of this retrospective multicentre cohort study was to show the feasibility and survival of repeated resection of ICC recurrence. Methods Data were collected from 18 German hepato-pancreatico-biliary centres for patients who underwent repeated exploration of recurrent ICC between January 2008 and December 2017. Primary end points were overall (OS) and recurrence-free survival from the day of primary and repeated resection. Results Of 156 patients who underwent repeated exploration for recurre…

medicine.medical_specialtyResectionCholangiocarcinomaCohort Studies03 medical and health sciences0302 clinical medicineMedicineHepatectomyHumansIntrahepatic CholangiocarcinomaRetrospective StudiesHepatologybusiness.industryPrimary resectionRecurrent Intrahepatic Cholangiocarcinoma3. Good healthTumor recurrenceSurgeryTreatment OutcomeBile Duct NeoplasmsMedian timeCurative treatment030220 oncology & carcinogenesis030211 gastroenterology & hepatologyNeoplasm Recurrence LocalbusinessCohort studyLiver international : official journal of the International Association for the Study of the LiverReferences
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Meta-analysis of Randomized Controlled Trials and Individual Patient Data Comparing Minimally Invasive With Open Oesophagectomy for Cancer

2021

Minimally invasive oesophagectomy (MIO) for oesophageal cancer may reduce surgical complications compared with open oesophagectomy. MIO is, however, technically challenging and may impair optimal oncological resection. The aim of the present study was to assess if MIO for cancer is beneficial.A systematic literature search in MEDLINE, Web of Science and CENTRAL was performed and randomized controlled trials (RCTs) comparing MIO with open oesophagectomy were included in a meta-analysis. Survival was analysed using individual patient data. Random-effects model was used for pooled estimates of perioperative effects.Among 3219 articles, six RCTs were identified including 822 patients. Three-yea…

medicine.medical_specialtyEsophageal Neoplasmsmedicine.medical_treatment610 Medicine & healthLower risklaw.inventionRandomized controlled triallawOpen ResectionMedicineHumansMinimally Invasive Surgical ProceduresRandomized Controlled Trials as Topic10217 Clinic for Visceral and Transplantation Surgerybusiness.industryCancerOdds ratioPerioperativeLength of Staymedicine.diseaseSurgery2746 SurgeryEsophagectomyTreatment OutcomeEsophagectomyMeta-analysisSurgerybusiness
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