0000000000154725

AUTHOR

David Hopkins

showing 11 related works from this author

Direct and correlated responses to bi-directional selection on pre-adult development time in Drosophila montana.

2019

Selection experiments offer an efficient way to study the evolvability of traits that play an important role in insects’ reproduction and/or survival and to trace correlations and trade-offs between them. We have exercised bi-directional selection on Drosophila montana flies’ pre-adult development time under constant light and temperature conditions for 10 generations and traced the indirect effects of this selection on females’ diapause induction under different day lengths, as well as on the body weight and cold tolerance of both sexes. Overall, selection was successful towards slow, but not towards fast development. However, all fast selection line replicates showed at the end of selecti…

0106 biological sciences0301 basic medicineMalePhysiologymahlakärpäsetmedia_common.quotation_subjectAcclimatizationPhotoperiodCircadian clockevoluutiopre-adult developmental timeZoologyreproductive diapauseDiapauseBiologyDiapause Insect01 natural sciencestalvehtiminenbi-directional selection experimentbody weight03 medical and health scienceskylmänkestävyysControl lineAnimalsCircadian rhythmpaino (fysiikka)Selection GeneticSelection (genetic algorithm)media_commonvuorokausirytmiluonnonvalintaDirectional selectionBody WeightPupacold tolerancecritical day lengthEvolvabilityCold Temperature010602 entomology030104 developmental biologyInsect ScienceLarvata1181DrosophilaFemaleReproductionJournal of insect physiology
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Corrigendum to “Soil fungal community composition does not alter along a latitudinal gradient through the maritime and sub-Antarctic” Fungal Ecology …

2012

0106 biological sciencesEcologyFungal ecologyEcologyEcological ModelingEnvironmental ethicsPlant ScienceBiologySub antarctic010603 evolutionary biology01 natural sciencesCommunity compositionEcology Evolution Behavior and Systematics010606 plant biology & botanyFungal Ecology
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A health promotion intervention to improve lifestyle choices and health outcomes in people with psychosis: a research programme including the IMPaCT …

2020

Background People with psychotic disorders have reduced life expectancy largely because of physical health problems, especially cardiovascular disease, that are complicated by the use of tobacco and cannabis. Objectives We set out to (1) chart lifestyle and substance use choices and the emergence of cardiometabolic risk from the earliest presentation with psychosis, (2) develop a pragmatic health promotion intervention integrated within the clinical teams to improve the lifestyle choices and health outcomes of people with psychosis and (3) evaluate the clinical effectiveness and cost-effectiveness of that health promotion intervention. Design We performed a longitudinal cohort study of peo…

dysglycaemiamedicine.medical_specialtyhealth promotionMotivational interviewingmotivational interviewinglaw.invention03 medical and health sciences0302 clinical medicineQuality of life (healthcare)Randomized controlled triallawIntervention (counseling)medicinepsychosis030212 general & internal medicinerctFirst episodelifestyle choicesbusiness.industrylcsh:Public aspects of medicineweightlcsh:RA1-1270waist circumferenceMental health030227 psychiatryHealth promotionquality of lifeFamily medicineLife expectancybusinessphysical healthmental healthProgramme Grants for Applied Research
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Soil fungal community composition does not alter along a latitudinal gradient through the maritime and sub-Antarctic

2012

We investigated the relationships between fungal community composition, latitude and a range of physicochemical parameters in 58 soils sampled from a 2370 km latitudinal gradient between South Georgia (54 S, 38 W) in the sub-Antarctic and Mars Oasis (72 S, 68 W) on Alexander Island in the southern maritime Antarctic. Our study, which is based on approximately ten times the number of samples used in previous similar studies, indicates that latitude and its associated environmental parameters are not related to fungal community composition. Significant changes in the composition of soil fungal communities were observed in relation to gradients of the ratio of total organic carbon to nitrogen,…

Total organic carbonAntarctica C:N ratio Extreme environments Latitudinal gradient pH Soil fungal community composition0303 health sciencesEcology030306 microbiologyRange (biology)EcologyEcological ModelingSettore AGR/13 - Chimica AgrariaPlant ScienceMars Exploration Program15. Life on landBiologyLatitude03 medical and health sciencesOceanographyCommunity compositionSoil pHSoil waterExtreme environment14. Life underwaterEcology Evolution Behavior and Systematics030304 developmental biologyFungal Ecology
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Biogeochemical responses to nutrient, moisture and temperature manipulations of soil from Signy Island, South Orkney Islands in the Maritime Antarctic

2014

AbstractWe have investigated how the microbially-driven processes of carbon (C) mineralization (respiration) and nitrogen (N) mineralization/immobilization in a soil from the northern Maritime Antarctic respond to differences in water availability (20% and 80% water-holding capacity) and temperature (5°C and 15°C) in the presence and absence of different organic substrates (2 mg C as either glucose, glycine or tryptone soy broth (TSB) powder (a complex microbial growth medium)) in a controlled laboratory experiment over 175 days. Soil respiration and N mineralization/immobilization in the presence of a C-rich substrate (glucose) increased with increases in water and temperature. These facto…

Biogeochemical cycleMoistureChemistrySettore AGR/13 - Chimica Agrariacarbon mineralization nitrogen mineralization organic substrates soil respiration warming water additionGeologyMineralization (soil science)OceanographySoil respirationNutrientEnvironmental chemistryBotanyRespirationCyclingNitrogen cycleEcology Evolution Behavior and SystematicsAntarctic Science
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Plant litter decomposition and microbial characteristics in volcanic soils (Mt Etna, Sicily) at different stages of development

2006

Soils at different developmental stages were sampled from eight sites on the slopes of Mt Etna, Sicily (Italy) and characterized for total C, microbial biomass and microbial respiration. The values of these parameters were greatest for the most developed soils, but differences in recent management and site characteristics limited analysis of trends with soil development across the eight sites. The decomposition kinetics of both intact leaf litter and the water-insoluble fraction of leaf litter from three common species on Etna [Etnean broom (Genista aetnensis), European chestnut (Castanea sativa), and Corsican pine (Pinus nigra)] were determined in four of the soils (the two with the smalle…

Biomass (ecology)Genista aetnensisBroomSoil ScienceGenistaBiologyPlant litterbiology.organism_classificationMicrobiologyCommon speciesSoil waterBotanyLitterCarbon . Castanea sativa . Decomposition . Genista aetnensis . Litter quality . Pinus nigra . RespirationAgronomy and Crop Science
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Structural diversity and enzyme activity of volcanic soils at different stages of development and response to experimental disturbance

2008

We investigated the phospholipid fatty acid (PLFA) diversity and enzyme activities in soils from the volcano, Mt. Etna (Sicily). The soils were at sites which have been developing for different periods of time and have formed in volcanic lava of differing ages that have been supplemented with volcanic ejecta from subsequent eruptions. However, the plant communities indicated a marked successional difference between the sites and we have used this as a proxy for developmental stage. We have compared the structural and functional properties of the microbial communities in soils from the two sites and tested experimentally the hypothesis that the more diverse community was more resistant and r…

geographygeography.geographical_feature_categorybiologyLavaEcologySettore AGR/13 - Chimica AgrariaAcid phosphataseSoil SciencePlant communityMicrobiologyEnzyme assayVolcanoMicrobial population biologySoil waterbiology.proteinArylsulfatasePLFA Enzyme activity Volcanic Development Disturbance
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Selection for reproduction under short photoperiods changes diapause-associated traits and induces widespread genomic divergence.

2019

The work has been supported by the Academyof Finland to A.H. (project 267244) and Natural Environment Research Council (NERC) funding (NE/J020818/1 to M.G.R.; NE/L501852/1 to R.A.W.W.). The incidence of reproductive diapause is a critical aspect of life history in overwintering insects from temperate regions. Much has been learned about the timing, physiology and genetics of diapause in a range of insects, but how the multiple changes involved in this and other photoperiodically regulated traits are inter-related is not well understood. We performed quasinatural selection on reproduction under short photoperiods in a northern fly species, Drosophila montana, to trace the effects of photoper…

0106 biological sciencesPhysiology030310 physiologyQH301 BiologyCircadian clockGenome Insect01 natural sciencestalvehtiminenkylmänkestävyyscircadian clockmedia_commonvuorokausirytmi0303 health sciencesluonnonvalintagenome analysesReproductionPhenotypeAdaptation PhysiologicalCircadian RhythmCold TemperatureDrosophila melanogasterPhenotypeFemaleReproductionLocomotionendocrine systemmahlakärpäsetPeriod (gene)media_common.quotation_subjectPhotoperiodZoologyreproductive diapausefotobiologiaAquatic ScienceDiapauseBiology010603 evolutionary biology03 medical and health sciencesQH301Quantitative Trait Heritablephotoperiodic timerAnimalsCircadian rhythmMolecular BiologyGeneEcology Evolution Behavior and SystematicsSelection (genetic algorithm)Critical day lenghtGenetic VariationDAScold tolerancelisääntyminenDiapauseChromosomes Insectcritical day lengthInsect ScienceperimähyönteisetLinear ModelsAnimal Science and ZoologyThe Journal of experimental biology
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Microbial community structure in soils with decomposing residues from plants with genetic modifications to lignin biosynthesis

2006

Lignin is a major determinant of the decomposition of plant materials in soils. Advances in transgenic technology have led to the possibility of modifying lignin to improve the pulping properties of plant materials for papermaking. Previous studies have shown that lignin modifications also affect the rate of plant material decay in soil. The aim of this work was to investigate short-term changes in soil microbial community structures when tobacco residues with reduced activity of enzymes in the monolignol pathway decompose. The residues from lignin-modified plants all decomposed faster than unmodified plant materials. The relative proportions of some of the structural groups of microbial ph…

PaperNitrogenAlcohol oxidoreductaseLignincomplex mixturesMicrobiologysoilchemistry.chemical_compoundTobaccoBotanyGeneticsgenetic modificationLigninMolecular BiologySoil MicrobiologydecompositionBacteriaPlant StemsbiologyfungiFungifood and beveragesMethyltransferasesPlants Genetically Modifiedbiology.organism_classificationDecompositionCarbonAlcohol Oxidoreductases[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyMicrobial population biologychemistrymicrobial community structureSoil waterMonolignolSoil microbiologyBacteriaFEMS Microbiology Letters
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Responses to increases in temperature of heterotrophic micro-organisms in soils from the maritime Antarctic

2015

Understanding relationships between environmental changes and soil microbial respiration is critical for predicting changes in soil organic carbon (SOC) fluxes and content. The maritime Antarctic is experiencing one of the fastest rates of warming in the world and is therefore a key location to examine the effect of temperature on SOC mineralization by the respiration of soil micro-organisms. However, depletion of the labile substrates at higher temperatures relative to the total SOC and greater temperature sensitivity of recalcitrant components of the SOC confound simple interpretations of the effects of warming. We have addressed these issues by testing the hypothesis that respiration by …

Soil organic matterEcologySoil organic matterSettore AGR/13 - Chimica AgrariaMineralization (soil science)Soil carbonBiologySoil respirationchemistry.chemical_compoundCarbon dioxideAgricultural and Biological Sciences (all)chemistryThermalEnvironmental chemistryCarbon dioxideRespirationSoil watersense organsGeneral Agricultural and Biological SciencesRespiration rateAcclimationPolar Biology
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40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004

2004

0303 health sciencesmedicine.medical_specialtybusiness.industryEASDEndocrinology Diabetes and MetabolismHuman physiologymedicine.disease03 medical and health sciences0302 clinical medicineDiabetes mellitusFamily medicineInternal MedicineMedicinebusiness030217 neurology & neurosurgery030304 developmental biology
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