0000000000156915

AUTHOR

Kristin Klemmetsby Solli

showing 2 related works from this author

Patients’ experiences of continued treatment with extended-release naltrexone: a Norwegian qualitative study

2022

Abstract Background The opioid antagonist extended-release naltrexone (XR-NTX) in the treatment of opioid use disorder (OUD) is effective in terms of safety, abstinence from opioid use and retention in treatment. However, it is unclear how patients experience and adjust to losing the possibility of achieving an opioid effect. This qualitative study is the first to explore how people with opioid dependence experience XR-NTX treatment, focusing on the process of treatment over time. Methods Using a purposive sampling strategy, semi-structured interviews were undertaken with 19 persons with opioid use disorder (15 men, four women, 22–55 years of age) participating in a clinical trial of XR-NTX…

AdultMaleNarcotic AntagonistsGeneral MedicineMiddle AgedOpioid-Related DisordersInjections IntramuscularNaltrexoneAnalgesics OpioidYoung AdultVDP::Medisinske Fag: 700::Helsefag: 800Delayed-Action PreparationsHumansFemale
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‘Not at all what I had expected’: Discontinuing treatment with extended-release naltrexone (XR-NTX): A qualitative study

2021

Background: Extended-release naltrexone (XR-NTX), an opioid antagonist, has demonstrated equal treatment outcomes, in terms of safety, opioid use, and retention, to the recommended OMT medication buprenorphine. However, premature discontinuation of XR-NTX treatment is still common and poorly understood. Research on patient experiences of XR-NTX treatment is limited. We sought to explore participants' experiences with discontinuation of treatment with XR-NTX, particularly motivation for XR-NTX, experiences of initiation and treatment, and rationale for leaving treatment. Methods: We conducted qualitative, semi-structured interviews with participants from a clinical trial of XR-NTX. The study…

Malemedicine.medical_specialtymedicine.drug_classNarcotic Antagonistsmedia_common.quotation_subjectMedicine (miscellaneous)Injections IntramuscularNaltrexonemedicineHumansVDP::Medisinske Fag: 700PsychiatryQualitative Researchmedia_commonbusiness.industryClinical Studies as TopicAbstinenceOpioid-Related DisordersNaltrexoneBuprenorphineDiscontinuationAnalgesics OpioidClinical trialPsychiatry and Mental healthClinical PsychologyVDP::Medisinske Fag: 700::Helsefag: 800Delayed-Action PreparationsFemalePshychiatric Mental HealthThematic analysisbusinesshuman activitiesOpioid antagonistQualitative researchmedicine.drugBuprenorphine
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