0000000000161396
AUTHOR
J. Valle
showing 2 related works from this author
The Vegf Pathway in Patients with Pancreatic Neuroendocrine Tumors: Efficacy of Everolimus by Baseline Marker Level, and Prognostic and Predictive Ef…
2012
ABSTRACT Background RADIANT-3 was a phase III study investigating the effect of the mammalian target of rapamycin inhibitor everolimus on progression-free survival (PFS) in patients with advanced pancreatic neuroendocrine tumors (pNET; Yao et al, NEJM, 2011). Everolimus significantly improved PFS compared with placebo (11 vs 4.6 months, P Methods Baseline plasma levels of VEGF-A, PlGF, sVEGFR1, and sVEGFR2 were determined by ELISA using multiplexed MSD platform. The optimal cutoffs for these markers were explored using the “survival tree analysis” method. Interaction of treatment and baseline marker status ( Results PFS was significantly improved to a similar extent in patients receiving e…
Updated global analysis of the atmospheric neutrino data in terms of neutrino oscillations
2000
A global analysis of all the available atmospheric neutrino data is presented in terms of neutrino oscillations in the nu_mu -> nu_tau and nu_mu -> nu_s channels, where nu_s denotes a sterile neutrino. We perform our analysis of the contained events data as well as the upward-going neutrino-induced muon fluxes. In addition to the previous data samples of Frejus, Nusex, IMB and Kamioka experiments, we include the full data set of the 52 kton-yr of Super-Kamiokande, the recent 4.6 kton-yr contained events of Soudan2 and the results on upgoing muons from the MACRO and Baksan detectors. From the statistical analysis it emerges that the nu_mu -> nu_tau channel provides the best agreemen…