0000000000161464
AUTHOR
E. Roca
showing 2 related works from this author
The Vegf Pathway in Patients with Pancreatic Neuroendocrine Tumors: Efficacy of Everolimus by Baseline Marker Level, and Prognostic and Predictive Ef…
2012
ABSTRACT Background RADIANT-3 was a phase III study investigating the effect of the mammalian target of rapamycin inhibitor everolimus on progression-free survival (PFS) in patients with advanced pancreatic neuroendocrine tumors (pNET; Yao et al, NEJM, 2011). Everolimus significantly improved PFS compared with placebo (11 vs 4.6 months, P Methods Baseline plasma levels of VEGF-A, PlGF, sVEGFR1, and sVEGFR2 were determined by ELISA using multiplexed MSD platform. The optimal cutoffs for these markers were explored using the “survival tree analysis” method. Interaction of treatment and baseline marker status ( Results PFS was significantly improved to a similar extent in patients receiving e…
Role of extension and compression in the evolution of the eastem margin of Iberia: the ESCI- València Trough seismic profile
1994
Carlos.Santisteban@uv.es The ESCI-València Trough deep seismic reflection profile crosses the eastern margin of Iberia and can be divided into three regions according to crustal structure. From NW to SE they are: a) the Ebro Basin, whit a 33 km thick continental crust wich remained almost undeformed during the Cenozoic and is very reflective in its lower part; b) the Continental Margin, made up of the Catalan-Valencian Domain and the Balearic Promontory with a thin (12 to 30 km thick) continental crust wich was deformed during the Cenozoic, extensional structures predominating the first domain and contractional structures in the second; and c) the Algerian Basin, with a 9 km thick oceanic c…