0000000000163253

AUTHOR

Johannes Mellinghoff

0000-0002-5455-8953

showing 4 related works from this author

Postoperative continuous positive airway pressure to prevent pneumonia, re-intubation, and death after major abdominal surgery (PRISM): a multicentre…

2021

BackgroundRespiratory complications are an important cause of postoperative morbidity. We aimed to investigate whether continuous positive airway pressure (CPAP) administered immediately after major abdominal surgery could prevent postoperative morbidity.MethodsPRISM was an open-label, randomised, phase 3 trial done at 70 hospitals across six countries. Patients aged 50 years or older who were undergoing elective major open abdominal surgery were randomly assigned (1:1) to receive CPAP within 4 h of the end of surgery or usual postoperative care. Patients were randomly assigned using a computer-generated minimisation algorithm with inbuilt concealment. The primary outcome was a composite of…

Pulmonary and Respiratory Medicinemedicine.medical_treatmentPopulationNO03 medical and health sciences0302 clinical medicineCPAPAbdomenSettore MED/41 - ANESTESIOLOGIAIntubation IntratrachealmedicineHumansIntubation030212 general & internal medicineContinuous positive airway pressureAdverse effecteducationeducation.field_of_studyContinuous Positive Airway Pressurebusiness.industryrespiratory complications; continuous positive airway pressure; major abdominal surgeryPneumoniaMiddle Agedmedicine.diseaserespiratory tract diseasesIntratrachealPneumoniaTreatment Outcome030228 respiratory systemRespiratory failureAnesthesiaVomitingmedicine.symptomRespiratory InsufficiencyIntubationbusinessAbdominal surgery
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Corrigendum to “Personal protective equipment and intensive care unit healthcare worker safety in the COVID-19 Era (PPE-SAFE): An international surve…

2021

The authors regret errors were present in the published article. Counts of some of the adverse events were erroneous. Changes to the text include. Last sentence of the abstract should read. Adverse effects of PPE included heat (1266, 51%), thirst (1174, 47%), pressure areas (1088, 44%), headaches (696, 28%), Inability to use the bathroom (661, 27%) and extreme exhaustion (492, 20%). All but pressure areas were associated with longer shift durations. Last sentence of the results section of the manuscript should read. All but pressure areas were associated with longer duration of shifts wearing PPE (Table 4). Table 1 the total number of community/urban type of hospital should read 740 instead…

Extreme exhaustionCoronavirus disease 2019 (COVID-19)masks COVID19business.industryMEDLINEInternational surveyHealthcare worker030208 emergency & critical care medicineRegretmedicine.diseaseCritical Care and Intensive Care MedicineIntensive care unitlaw.invention03 medical and health sciences0302 clinical medicine030228 respiratory systemlawMedicineMedical emergencyCorrigendumbusinessPersonal protective equipmentJournal of Critical Care
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Personal protective equipment and intensive care unit healthcare worker safety in the COVID-19 era (PPE-SAFE): An international survey

2020

Purpose To survey healthcare workers (HCW) on availability and use of personal protective equipment (PPE) caring for COVID-19 patients in the intensive care unit (ICU). Materials and method A web-based survey distributed worldwide in April 2020. Results We received 2711 responses from 1797 (67%) physicians, 744 (27%) nurses, and 170 (6%) Allied HCW. For routine care, most (1557, 58%) reportedly used FFP2/N95 masks, waterproof long sleeve gowns (1623; 67%), and face shields/visors (1574; 62%). Powered Air-Purifying Respirators were used routinely and for intubation only by 184 (7%) and 254 (13%) respondents, respectively. Surgical masks were used for routine care by 289 (15%) and 47 (2%) for…

Face shieldMalebusiness.product_categoryHot TemperatureInfectious Disease TransmissionAllied Health PersonnelNursesCritical Care and Intensive Care MedicineOccupational safety and healthlaw.inventionPatient-to-Professional0302 clinical medicinelawSurveys and QuestionnairesPersonal protective equipmentHealth careMedicine and Health SciencesViralRespiratorRespiratory Protective DevicesHealth care workersHealth services researchHeadacheMasksMiddle AgedIntensive care unitEuropeIntensive Care UnitsFemaleSafetyCoronavirus InfectionsEye Protective DevicesThirstAdultmedicine.medical_specialtyCOVID-19; Health care workers; Intensive care; Personal protective equipment; Safety; Adult; Africa; Allied Health Personnel; Asia; Betacoronavirus; COVID-19; Coronavirus Infections; Europe; Eye Protective Devices; Female; Gloves Protective; Headache; Hot Temperature; Humans; Infectious Disease Transmission Patient-to-Professional; Intensive Care Units; Male; Masks; Middle Aged; North America; Nurses; Oceania; Pandemics; Personal Protective Equipment; Personnel Staffing and Scheduling; Physicians; Pneumonia Viral; Respiratory Protective Devices; SARS-CoV-2; South America; Surgical Attire; Surveys and Questionnaires; Thirst; Health Personnel; Occupational HealthInfectious Disease Transmission Patient-to-ProfessionalAsiaHealth PersonnelPneumonia ViralGlovesOceaniaPersonnel Staffing and SchedulingArticle03 medical and health sciencesBetacoronavirusIntensive carePhysiciansmedicineHumansSurgical AttirePersonal protective equipmentPandemicsOccupational Healthbusiness.industrySARS-CoV-2COVID-19030208 emergency & critical care medicinePneumoniaSouth AmericaProtective030228 respiratory systemCOVID-19Personal protective equipmentSafety Health care workersIntensive careIntensive careEmergency medicineAfricaNorth AmericabusinessGloves ProtectiveJournal of Critical Care
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Epidemiological characteristics, practice of ventilation, and clinical outcome in patients at risk of acute respiratory distress syndrome in intensiv…

2016

Background Scant information exists about the epidemiological characteristics and outcome of patients in the intensive care unit (ICU) at risk of acute respiratory distress syndrome (ARDS) and how ventilation is managed in these individuals. We aimed to establish the epidemiological characteristics of patients at risk of ARDS, describe ventilation management in this population, and assess outcomes compared with people at no risk of ARDS. Methods PRoVENT (PRactice of VENTilation in critically ill patients without ARDS at onset of ventilation) is an international, multicentre, prospective study undertaken at 119 ICUs in 16 countries worldwide. All patients aged 18 years or older who were rece…

MalePediatricsARDSmedicine.medical_treatmentlaw.inventionPositive-Pressure Respiration0302 clinical medicinelawRisk FactorsPrevalenceventilator–induced lung injuryProspective StudiesHospital MortalityProspective cohort studyTidal volumeeducation.field_of_studyRespiratory Distress SyndromeAcute respiratory distress syndrometidal volumeARDS critically ill ventilationMiddle AgedIntensive care unitIntensive Care UnitsCritical IllneFemaleHumanPulmonary and Respiratory Medicinemedicine.medical_specialtyCritical IllnessPopulationIntensive Care UnitLung injurymechanical ventilationNO03 medical and health sciencesIntensive caremedicineAcute respiratory distress syndrome mechanical ventilation ventilator–induced lung injury tidal volume positive end–expiratory pressureHumansMED/41 - ANESTESIOLOGIAeducationAgedMechanical ventilationbusiness.industryRisk FactorRespiratory Distress Syndrome Adult030208 emergency & critical care medicinemedicine.diseaseRespiration ArtificialMechanical ventilation Acute respiratory failure Acute respiratory distress syndromeProspective Studie030228 respiratory systemEmergency medicinepositive end–expiratory pressurebusiness
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