0000000000164130

AUTHOR

Lukas Stolz

showing 4 related works from this author

Impact of Proportionality of Secondary Mitral Regurgitation on Outcome After Transcatheter Mitral Valve Repair

2020

The purpose of this paper was to evaluate the impact of proportionality of secondary mitral regurgitation (SMR) in a large real-world registry of transcatheter edge-to-edge mitral valve repair (TMVr) BACKGROUND: Differences in the outcomes of recent randomized trials of TMVr for SMR may be explained by the proportionality of SMR severity to left ventricular (LV) volume.The ratio of pre-procedural effective regurgitant orifice area (EROA) to LV end-diastolic volume (LVEDV) was retrospectively assessed in patients undergoing TMVr for severe SMR between 2008 and 2019 from the EuroSMR registry. A recently proposed SMR proportionality scheme was adapted to stratify patients according to EROA/LVE…

medicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentRenal function030204 cardiovascular system & hematology030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinePredictive Value of TestsInternal medicinemedicineNatriuretic peptideHumansRadiology Nuclear Medicine and imagingRetrospective StudiesBody surface areaMitral valve repairMitral regurgitationEjection fractionbusiness.industryMortality rateMitral Valve Insufficiencymedicine.diseaseTreatment OutcomeHeart failureQuality of LifeCardiologyMitral ValveCardiology and Cardiovascular MedicinebusinessJACC: Cardiovascular Imaging
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Impact of Right Ventricular Dysfunction on Outcomes After Transcatheter Edge-to-Edge Repair for Secondary Mitral Regurgitation

2021

OBJECTIVES This study sought to assess the impact of right ventricular dysfunction (RVD) as defined by impaired right ventricular-to-pulmonary artery (RV-PA) coupling, on survival after edge-to-edge transcatheter mitral valve repair (TMVR) for severe secondary mitral regurgitation (SMR). BACKGROUND Conflicting data exist regarding the benefit of TMVR in severe SMR. A possible explanation could be differences in RVD. METHODS Using data from the EuroSMR (European Registry on Outcomes in Secondary Mitral Regurgitation) registry, this study compared the characteristics and outcomes of SMR patients undergoing TMVR, according to their RV-PA coupling, assessed by tricuspid annular plane systolic e…

medicine.medical_specialtyAdverse outcomesVentricular Dysfunction Right030204 cardiovascular system & hematology030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinePredictive Value of TestsInternal medicinemedicine.arterymedicineHumansRadiology Nuclear Medicine and imagingIn patientCardiac Surgical Procedures610 Medicine & healthMitral regurgitationbusiness.industryMitral Valve InsufficiencyRight ventricular dysfunctionTreatment Outcomemedicine.anatomical_structurePulmonary arteryCardiologyTranscatheter mitral valve repairCardiology and Cardiovascular MedicinebusinessArteryJACC: Cardiovascular Imaging
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Sex-Related Clinical Characteristics and Outcomes of Patients Undergoing Transcatheter Edge-to-Edge Repair for Secondary Mitral Regurgitation.

2021

OBJECTIVES The authors sought to assess sex-based differences in characteristics and outcomes of patients undergoing transcatheter edge-to-edge mitral valve repair (TMVR) for secondary mitral regurgitation (SMR). BACKGROUND Subgroup analysis from the COAPT (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart��Failure Patients with Functional Mitral Regurgitation) trial indicated potential sex-related differences in outcomes after TMVR. The impact of sex on results after TMVR in a real-world setting is unknown. METHODS The authors assessed clinical outcomes and echocardiographic parameters in women and men undergoing TMVR for SMR between 2008 and 2018 who were …

Malemedicine.medical_specialtymedicine.medical_treatmentSubgroup analysis030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineQuality of lifeInternal medicineMedicineHumans030212 general & internal medicine610 Medicine & healthHeart FailureHeart Valve Prosthesis ImplantationMitral regurgitationMitral valve repairbusiness.industryMitraClipHazard ratioMitral Valve InsufficiencySex relatedmedicine.diseaseTreatment OutcomeEchocardiographyHeart failureQuality of LifeFemaleCardiology and Cardiovascular MedicinebusinessJACC. Cardiovascular interventions
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Impact of Residual Mitral Regurgitation on Survival After Transcatheter Edge-to-Edge Repair for Secondary Mitral Regurgitation.

2021

OBJECTIVES The aim of this study was to assess the impact of residual mitral regurgitation (resMR) on mortality with respect to left ventricular dilatation (LV-Dil) or right ventricular dysfunction (RV-Dys) in patients with secondary mitral regurgitation (SMR) who underwent mitral valve transcatheter edge-to-edge repair (TEER). BACKGROUND The presence of LV-Dil and RV-Dys correlates with advanced stages of heart failure in SMR patients, which may impact the outcome after TEER. METHODS SMR patients in a European multicenter registry were evaluated. Investigated outcomes were 2-year all-cause mortality and improvement in New York Heart Association functional class with respect to MR reduction…

medicine.medical_specialtyVentricular Dysfunction Right030204 cardiovascular system & hematologyNew york heart association03 medical and health sciences0302 clinical medicineInternal medicinemedicine.arteryMitral valvemedicineHumans030212 general & internal medicineCardiac Surgical Procedures610 Medicine & healthHeart FailureMitral regurgitationbusiness.industryMortality rateHazard ratioMitral Valve Insufficiencymedicine.diseaseConfidence intervalmedicine.anatomical_structureTreatment OutcomeHeart failurePulmonary arteryCardiologyCardiology and Cardiovascular MedicinebusinessJACC. Cardiovascular interventions
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