0000000000164958

AUTHOR

Enzo Pasquale Scilingo

showing 5 related works from this author

Quantification of Different Regulatory Pathways Contributing to Heartbeat Dynamics during Multiple Stimuli: a Proof of the Concept.

2019

The dynamical interplay between brain and heart is mediated by several feedback mechanisms including the central autonomic network and baroreflex loop at a peripheral level, also for a short-term regulation. State of the art focused on the characterization of each regulatory pathway through a single stressor elicitation. However, no studies targeted the actual quantification of different mediating routes leading to the generation of heartbeat dynamics, particularly in case of combined exogenous stimuli. In this study, we propose a new approach based on computational modeling to quantify the contribution of multiple concurrent stimuli in modulating cardiovascular dynamics. In this prelimina…

HeartbeatComputer scienceStressorHealthy subjectsHeart Rate VariabilityHeartPhysiological Modelling030204 cardiovascular system & hematologyBaroreflexAutonomic Nervous SystemBiomedical Signal ProcessingCardiovascular System03 medical and health sciences0302 clinical medicineDynamics (music)Heart RateStress PhysiologicalSettore ING-INF/06 - Bioingegneria Elettronica E InformaticaHeart rate variabilityHumansRegulatory PathwayNeuroscience030217 neurology & neurosurgeryStress PsychologicalAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
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Quantifying multidimensional control mechanisms of cardiovascular dynamics during multiple concurrent stressors

2021

Heartbeat regulation is achieved through different routes originating from central autonomic network sources, as well as peripheral control mechanisms. While previous studies successfully characterized cardiovascular regulatory mechanisms during a single stressor, to the best of our knowledge, a combination of multiple concurrent elicitations leading to the activation of different autonomic regulatory routes has not been investigated yet. Therefore, in this study, we propose a novel modeling framework for the quantification of heartbeat regulatory mechanisms driven by different neural routes. The framework is evaluated using two heartbeat datasets gathered from healthy subjects undergoing p…

HeartbeatTilt testComputer scienceCold pressor test0206 medical engineeringEmotionsBiomedical Engineering02 engineering and technologyStressAutonomic Nervous SystemCardiovascular System030218 nuclear medicine & medical imaging03 medical and health sciencesNeural activity0302 clinical medicineHeart RateHumansCentral autonomic networkCardiac controlControl (linguistics)Heart rate variabilityStressorEmotion elicitationHealthy subjectsCognitionHeart020601 biomedical engineeringComputer Science ApplicationsPsychophysiologyCentral autonomic network; Cold pressor test; Emotion elicitation; Heart rate variability; Stress; Tilt test; Autonomic Nervous System; Emotions; Heart; Heart Rate; Humans; Cardiovascular SystemSettore ING-INF/06 - Bioingegneria Elettronica E InformaticaCentral autonomic network Cold pressor test Emotion elicitation Heart rate variability Stress Tilt testNeuroscience
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Causal brain-heart information transfer during visual emotional elicitation in healthy subjects: Preliminary evaluations and future perspectives

2017

Complex heartbeat dynamics is known to reflect subject's emotional state, thanks to numerous links to brain cortical and subcortical regions. Likewise, specific brain regions are deeply involved in vagally-mediated emotional processing and regulation. Nevertheless, although the brain-heart interplay has been studied during visual emotion elicitation, directional interactions have not been investigated so far. To fill this gap, in this study we investigate brain-heart dynamics during emotional elicitation in healthy subjects through measures of Granger causality (GC) between the two physiological systems. Data were gathered from 22 healthy volunteers who underwent pleasant/ unpleasant affect…

Information transferHeartbeatPhotic StimulationEmotionsBiomedical EngineeringSignal Processing; Biomedical Engineering; 1707; Health InformaticsHealth InformaticsElectroencephalography01 natural sciencesBrain mappingLateralization of brain function010305 fluids & plasmasDevelopmental psychology03 medical and health sciences0302 clinical medicineHeart Rate0103 physical sciencesmedicinePrefrontal cortexInternational Affective Picture System1707Brain Mappingmedicine.diagnostic_testBrainElectroencephalographyHealthy VolunteersSettore ING-INF/06 - Bioingegneria Elettronica E InformaticaSignal ProcessingPsychologyPhotic Stimulation030217 neurology & neurosurgeryCognitive psychology
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Towards Disentangling the Contribution of Different Pathways for the Regulation of Cardiac Activity: A Pilot Study

2020

Heartbeat is dynamically regulated through mediating routes associated with central and peripheral feedback mechanisms. Previous studies focused on the quantification of these mechanisms in the presence of a single stressor. In this pilot study we propose a model aimed to quantify the contribution of different heartbeat regulatory routes while multiple stressors are administrated to the subject. The model is tested with Heart rate Variability (HRV) series from 26 subjects undergoing physical and affective stressors. Results show that the physical stressor prevalently (74%) contributes in mediating cardiac vagal control dynamics in case of concurrent affective elicitation. These results may …

HeartbeatHeart rate Variabilitybusiness.industrySettore ING-INF/06 - Bioingegneria Elettronica E InformaticaStressorMedicineHeart rate variabilityCardiac activitybusinessNeuroscience
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Lateralization of directional brain-heart information transfer during visual emotional elicitation

2019

Previous studies have characterized the physiological interactions between central nervous system (brain) and peripheral cardiovascular system (heart) during affective elicitation in healthy subjects; however, questions related to the directionality of this functional interplay have been gaining less attention from the scientific community. Here, we explore brain-heart interactions during visual emotional elicitation in healthy subjects using measures of Granger causality (GC), a widely used descriptor of causal influences between two dynamical systems. The proposed approach inferences causality between instantaneous cardiovagal dynamics estimated from inhomogeneous point-process models of…

AdultInformation transferPhysiologyCentral nervous systemEmotions01 natural sciencesLateralization of brain function03 medical and health sciencesElectrocardiography0302 clinical medicineGranger causalityHeart RatePhysiology (medical)0103 physical sciencesmedicineinformation transferHumans010306 general physicsAffective computingaffective computingpoint processBrainElectroencephalographyHeartbrain-heart interactionAffective computing; Brain-heart interaction; Granger causality; Information transfer; Point processmedicine.anatomical_structureRespiratory Physiological PhenomenaGranger causalityFemalePsychologyNeuroscience030217 neurology & neurosurgeryPhotic Stimulation
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