NANOSTRUCTURED LIPID CARRIERS CONTAINING RILUZOLE AND PHARMACEUTICAL FORMULATIONS CONTAINING SAID PARTICLES

2008

The present invention concerns the preparation, the physical-chemical, technological and pharmaceutical characterization of Riluzole-loaded nanoparticle vectors. The chosen production technology permitted to obtain these systems in a reproducible way, with high yields and low costs. In particular, a novel formulation of Riluzole loaded into lipid nanoparticles was developed which is able to carry to the Central Nervous System a higher amount of drug in comparison with the free drug. In vivo results demonstrated that the administration on rats of these formulation permits to obtain a lower deposit of Riluzole in organs such as liver, spleen, heart and kidneys; the consequence is a reduction …

Cationic Solid-lipid nanoparticles as DNA carriers.

2006

Solid-lipid nanoparticles for gene delivery to cells.

2006

POLYMERIC NANOPARTICLES OBTAINED BY PHOTOCROSSLINKING OF AN ACRYLOYLATED POLYASPARTAMIDE IN INVERSE EMULSION

2004

PHOTOCROSSLINKED POLYMERIC NANOPARTICLES OBTAINED FROM AN ACRYLOYLATED POLYASPARTAMIDE

2004

SOLID LIPID NANOPARTICLES (SLN) AS DRUG CARRIERS FOR NEUROPROTECTIVE AGENTS: PREPARATION, CHARACTERIZATION AND RELEASE STUDIES

2007

NANOSTRUCTURED LIPID CARRIER (NLC) CONTAINING FERULIC ACID: PREPARATION, CARACTERIZATION AND CYTOTOXICITY STUDIES

2007

SOLID LIPID NANOPARTICLES CONTAINING AN ANTIOXIDANT COMPOUND IN ALZHEIMER’S DISEASE

2008

NANOSTRUCTURED LIPID CARRIERS (NLC) FOR POORLY-WATER SOLUBLE DRUGS: PREPARATION, CHARACTERISATION AND IN VITRO RELEASE STUDIES

2004

VETTORI NANOPARTICELLARI LIPIDICI CONTENENTI RILUZOLO E COMPOSIZIONI FARMACEUTICHE CHE LI CONTENGONO

2006

NANOPARTICELLE LIPIDICHE SOLIDE CATIONICHE COME VETTORI NON VIRALI DEL DNA

2007

SOLID LIPID NANOPARTICLES (SLNs) CONTAINING FERULIC ACID AGAINST OXIDATIVE STRESS IN NEURODEGENERATIVE DISEASES

2008

NANOPARTICLES CONTAINING RIVASTIGMINE FOR THE TREATMENT OF ALZHEIMER DISEASE

2007

Cationic solid-lipid nanoparticles for gene delivery.

2006

NEW PEGYLATED NANOPARTICLE SYSTEMS BASED ON POLYASPARTAMIDE DERIVATIVES

2006