OBSTRUCTED DEFECATION SYNDROME AND CHRONIC CONSTIPATION: CLINICAL AND SURGICAL ANALYSIS AND PSYCHOLOGICAL IMPLICATIONS

Chronic constipation and Obstructed defecation Syndrome (ODS) represent a high-incidence pathological status that severely compromise of Quality of Life (QoL). Our multidisciplinary study is aimed to investigate how the resolution of ODS by surgical technique can improve long-term clinical symptoms and the state of physical and mental health and QoL, focusing on the dual interaction between psyche and intestine Chronic constipation and Obstructed Defectaion Syndrome represent a high-incidence pathological status that severely compromise of Quality of Life. Our multidisciplinary study is aimed to investigate how the resolution of ODS by surgical technique can improve long-term clinical sympt…

A MIXTURE OF VEGETABLE EXTRACTS (CHAMOMILLE, PASSIONFLOWER, CARAWAY, FENNEL), AND ENZYMES (BETA-GALACTOSIDASE) FOR IRRITABLE BOWEL SYNDROME (ibs): AN OBSERVATIONAL STUDY ("BIOVES")

Summary. Aims: Irritable bowel syndrome (IBS) is a functional intestinal disorder. This syndrome may creates psychological disorders in patients who are affected and severely limits daily activities and lifestyle. Methods: We investigated the effect of the natural product consisting of chamomile, fennel, caraway, passionflower and melissa (Spasmicol®), on IBS patients. For the study, 187 patients with IBS, enrolled by primary care doctors, were treated with Spasmicol® (Aristeia Farmaceutici s.r.l.), two tablets/daily, for 30 days. At the end of the study, patients were re-evaluated to analyse the effects of therapy. Results: After 30 days, patients showed a marked reduction of symptoms (abd…

Antitumoral activity of curcumin: an adjuvant therapeutic strategy

Curcumin, an active substance contained in an Indian spice called turmeric or curcuma, is well known for its anti-inflammatory and antioxidant properties. In recent times, it was taken into account and studied as an antitumoral molecule, by relying on its interference on several biological mechanisms, such as the inhibition of inflammatory mediators, the enhancement of detoxifying enzymes’ action and processes of cell growth and proliferation. Studies show how the high dosage of curcumin in vitro inhibits colorectal tumor cells, pancreatic tumor cells, lung cancer cells and glioblastoma’s cells, interfering in signaling pathways as Wnt/β-catenin, NF-kB and PI3K/Akt and leading to cell cycle…

Antinflammatory effect of Levorag® (THD) emulgel on radiation proctocolitis around a colo-anal anastomosis

RECURRENT RETROPERITONEAL ABSCESS AFTER BILIARY TRACT SURGERY IN AN ELEDERLY PATIENT: A MINIMALLY INVASIVE NONSURGICAL APPROIACH AND ITS CONSEQUENCES: A CASE REPORT

Abstract Introduction Hepatic abscess can be defined as an encapsulated collection of suppurative material within the liver parenchyma. Hepatic abscess can be distinguished as pyogenic, amebic, or fungal. Biliary tract disease remains the most common cause of hepatic abscess today, and the most common complications range from pleural effusion, empyema, and bronchohepatic fistula to subphrenic abscess and rupture into the peritoneal cavity, stomach, colon, vena cava, or kidney. A large abscess compressing the inferior vena cava and the hepatic veins may result in Budd-Chiari syndrome. In this report, we present a rare case of hepatic abscess with an unusual evolution that was treated with a …