Intravesical gemcitabine in superficial bladder tumours preliminary results of a phase I-II study

INTRODUCTION & OBJECTIVES: Gemcttabme is a pro-drug requmng intracellular phosphorylation by deoxycytidine kinase to be activated. Preliminary experiences. suggesting the activtty and the good tolerability of the drug on superficial transitional cell carcinoma of the bladder (TCCB) when administered by intravesical route, have been recently published. The mm of the present study was to evaluate the ablative efftcacy of weekly intravesical instillations of gemcitabine against paptllary marker lesions left after TUR of superficial TCCB. The scientific background and the ethical acceptability of thts approach have been balidated by the European Organization for Research and Treatment ot Cancer…

Chromosomal polymorphism associated with Robertsonian fusion in Seriola dumerili (Risso, 1810) (Pisces: Carangidae)

The diploid numbers 2n= 48, and 2n= 47 have been determined for the greater amberjack, Seriola dumerili. A chromosome polymorphism due to Robertsonian fusion is present in this species. A simple sex-determining mechanism has not been observed.

UTILIZZO DI FONTI INFORMATIVE MULTIPLE E PUNTI DI CRITICITA’ PER INTERVENTI DI SANITA’ PUBBLICA IN TEMA DI MORTALITA’ INFANTILE. Un’esperienza condotta in SICILIA

La classificazione delle dipendenze e gli approcci teorici.

E' tutta questione di metodo. Dalle mafie tradizionali ai sistemi criminali

Leisure e costruzione dell’identità

Fici A., Cappello G., Macaluso M.,

.Chromosome sex determination and Y-autosome fusion in Blennius tentacularis Brunnich, 1765 (Pisces, Blennidae)

Diploid modal numbers of 2n=48 for females, and 2n=48 and 2n=47 for males of Blennius tentacularis caught in the Gulf of Palermo (Sicily) are established. Chromosome sex-determination is proposed for this species in which a Y-autosome fusion has been found.