0000000000167210

AUTHOR

Giuseppe M. Raffa

showing 2 related works from this author

Three-dimensional parametric modeling of bicuspid aortopathy and comparison with computational flow predictions

2016

Bicuspid aortic valve (BAV)-associated ascending aneurysmal aortopathy (namely “bicuspid aortopathy”) is a heterogeneous disease making surgeon predictions particularly challenging. Computational flow analysis can be used to evaluate the BAV-related hemodynamic disturbances, which likely lead to aneurysm enlargement and progression. However, the anatomic reconstruction process is time consuming so that predicting hemodynamic and structural evolution by computational modeling is unfeasible in routine clinical practice. The aim of the study was to design and develop a parametric program for three-dimensional (3D) representations of aneurysmal aorta and different BAV phenotypes starting fr…

MalePatient-Specific ModelingBicuspid aortic valveComputed Tomography AngiographyHeart Valve DiseasesBiomedical EngineeringMedicine (miscellaneous)Bioengineering—Three-dimensional anatomic reconstructionElectrocardiographyImaging Three-DimensionalBicuspid Aortic Valve DiseaseSettore ING-IND/12 - Misure Meccaniche E TermicheHumans—Finite-element analysiProspective StudiesAortaAgedRetrospective Studies—Aortic failureHemodynamicsModels CardiovascularComputational BiologySettore ING-IND/34 - Bioingegneria IndustrialeMiddle AgedBiomaterialAortic Aneurysm—Ascending thoracic aortic aneurysmAortic ValveFemaleStress MechanicalSoftware
researchProduct

Atlas-Based Evaluation of Hemodynamic in Ascending Thoracic Aortic Aneurysms

2021

Atlas-based analyses of patients with cardiovascular diseases have recently been explored to understand the mechanistic link between shape and pathophysiology. The construction of probabilistic atlases is based on statistical shape modeling (SSM) to assess key anatomic features for a given patient population. Such an approach is relevant to study the complex nature of the ascending thoracic aortic aneurysm (ATAA) as characterized by different patterns of aortic shapes and valve phenotypes. This study was carried out to develop an SSM of the dilated aorta with both bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV), and then assess the computational hemodynamic of virtual models ob…

Fluid Flow and Transfer ProcessesTechnologyQH301-705.5Process Chemistry and TechnologyTPhysicsQC1-999General Engineeringstatistical shape analysisSettore ING-IND/34 - Bioingegneria IndustrialeEngineering (General). Civil engineering (General)Computer Science Applicationscomputational fluid dynamicChemistryascending aortic aneurysmcardiovascular systemGeneral Materials Scienceascending aortic aneurysm; statistical shape analysis; computational fluid dynamicAscending aortic aneurysm Computational fluid dynamic Statistical shape analysisTA1-2040Biology (General)InstrumentationQD1-999Applied Sciences; Volume 12; Issue 1; Pages: 394
researchProduct