Author: Hervé Maisonneuve

0000000000172641

AUTHOR

Hervé Maisonneuve

showing 1 related works from this author

PET-adapted treatment for newly diagnosed advanced Hodgkin lymphoma (AHL2011): a randomised, multicentre, non-inferiority, phase 3 study

2019

International audience; Background: Increased-dose bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone (BEACOPPescalated) improves progression-free survival in patients with advanced Hodgkin lymphoma compared with doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD), but is associated with increased risks of haematological toxicity, secondary myelodysplasia or leukaemia, and infertility. We investigated whether PET monitoring during treatment could allow dose de-escalation by switching regimen (BEACOPPescalated to ABVD) in early responders without loss of disease control compared with standard treatment without PET monitoring.Methods: AHL201…

AdultMalemedicine.medical_specialtyVincristineDacarbazine[SDV]Life Sciences [q-bio]Salvage therapy[SDV.CAN]Life Sciences [q-bio]/CancerProcarbazineGastroenterology03 medical and health sciencesYoung Adult0302 clinical medicineInternal medicinehemic and lymphatic diseasesAntineoplastic Combined Chemotherapy ProtocolsMedicineHumansComputingMilieux_MISCELLANEOUSNeoplasm Stagingbusiness.industryStandard treatmentmedicine.diseaseHodgkin Disease3. Good healthVinblastineDrug Therapy Computer-Assisted[SDV] Life Sciences [q-bio]OncologyABVD030220 oncology & carcinogenesisPositron-Emission TomographyFemalebusinessFebrile neutropenia030215 immunologymedicine.drug

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PEPhysical Sciences and Engineering
- PE2Fundamental Constituents of Matter
  - PE2_1Theory of fundamental interactions
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- PE1Mathematics
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LSLife Sciences
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SHSocial Sciences and Humanities
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