0000000000174868

AUTHOR

M. Nakamura

showing 4 related works from this author

The magnet of the scattering and neutrino detector for the SHiP experiment at CERN

2019

The Search for Hidden Particles (SHiP) experiment proposal at CERN demands a dedicated dipole magnet for its scattering and neutrino detector. This requires a very large volume to be uniformly magnetized at B > 1.2 T, with constraints regarding the inner instrumented volume as well as the external region, where no massive structures are allowed and only an extremely low stray field is admitted. In this paper we report the main technical challenges and the relevant design options providing a comprehensive design for the magnet of the SHiP Scattering and Neutrino Detector.

TechnologyPhysics - Instrumentation and Detectorswigglers and undulators)magnet: designPermanent magnet devicesPhysics::Instrumentation and Detectorsengineering01 natural sciences7. Clean energy09 Engineering030218 nuclear medicine & medical imagingradiation hardened magnetsSubatomär fysik0302 clinical medicineDipole magnetSubatomic PhysicsNeutrino detectorsDetectors and Experimental TechniquesInstruments & InstrumentationInstrumentationphysics.ins-detAcceleration cavities and magnets superconducting (high-temperature superconductor; radiation hardened magnets; normal-conducting; permanent magnet devices; wigglers and undulators)Mathematical PhysicsPhysics02 Physical SciencesLarge Hadron ColliderInstrumentation and Detectors (physics.ins-det)magnet: technologyNuclear & Particles Physicsbending magnetneutrino: detectorNeutrino detectornormal-conductingAcceleration cavities and magnets superconducting (high-temperature superconductorproposed experimentCERN LabRadiation hardened magnetsFOS: Physical sciencesNormal-conductingAccelerator Physics and InstrumentationNuclear physics03 medical and health sciences0103 physical sciencespermanent magnet devices[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]Wigglers and undulators)normal-conducting magnetsScience & Technology010308 nuclear & particles physicsScatteringLarge detector systems for particle and astroparticle physicsAcceleratorfysik och instrumenteringLarge detector systems for particle physicsHigh temperature superconductors Neutrons Permanent magnets Ships Superconducting magnets Wigglers Astroparticle physics Comprehensive designs Massive structures Neutrino detectors Normal-conducting Radiation-hardened Ship experiments Technical challenges Particle detectorsVolume (thermodynamics)MagnetAcceleration cavities and magnets superconducting (high-temperature superconductor; Large detector systems for particle and astroparticle physics; Neutrino detectors; Normal-conducting; Permanent magnet devices; Radiation hardened magnets; Wigglers and undulators)High Energy Physics::Experimentneutrino detectors
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TH-302 + Gemcitabine (G + T) vs Gemcitabine (G) in Patients with Previously Untreated advanced Pancreatic Cancer (PAC)

2012

ABSTRACT Background TH-302 is a hypoxia targeted prodrug with a hypoxia-triggered 2-nitroimidazole component designed to release the DNA alkylator, bromo-isophosphoramide mustard (Br-IPM), when reduced in severe hypoxia. A randomized Phase 2B study (NCT01144455) was conducted to assess the benefit of G + T to standard dose G as first-line therapy of PAC. Materials and methods An open-label multi-center study of two dose levels of TH-302 (240 mg/m2 or 340 mg/m2) in combination with G versus G alone (randomized 1:1:1). G (1000 mg/m2) and T were administered IV over 30-60 minutes on Days 1, 8 and 15 of a 28-day cycle. Patients on the G could crossover after progression and be randomized to a G…

medicine.medical_specialtyGastrointestinal tumorsPerformance statusbusiness.industryHematologySevere hypoxiaNeutropeniamedicine.diseaseRashGastroenterologyDiscontinuationNon colorectalOncologyInternal medicineToxicitymedicinemedicine.symptombusinessAnnals of Oncology
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Corrigendum to ‘An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs’ [J Hepatol 2021;75(3)…

2022

It has come to our attention that the name of one of the authors in our manuscript was incorrectly spelled ‘Jinyoung Byan’; the correct spelling is ‘Jinyoung Byun’ as in the author list above. In addition, the excel files of the supplementary tables were not included during the online publication of our article. These have now been made available online. We apologize for any inconvenience caused.

PBC
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3C 279 Event Horizon Telescope imaging

2020

3C 279 is an archetypal blazar with a prominent radio jet that show broadband flux density variability across the entire electromagnetic spectrum. We use an ultra-high angular resolution technique - global Very Long Baseline Interferometry (VLBI) at 1.3mm (230GHz) - to resolve the innermost jet of 3C 279 in order to study its fine-scale morphology close to the jet base where highly variable gamma-ray emission is thought to originate, according to various models. The source was observed during four days in April 2017 with the Event Horizon Telescope (EHT) at 230 GHz, including the phased Atacama Large Millimeter/submillimeter Array (ALMA), at an angular resolution of ~20uarcsec (at a redshif…

observational astronomygalactic and extragalactic astronomyAstrophysics and AstronomyInterferometryAstrophysics::High Energy Astrophysical PhenomenaRadio galaxiesPhysicsGalaxiesNatural Sciences
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