0000000000175280

AUTHOR

Anna Nicolaou

0000-0001-8052-2201

showing 5 related works from this author

Artefact co-construction in virtual exchange: 'Youth Entrepreneurship for Society'

2020

The aim of this research study around the co-construction and sharing of authentic and meaningful artefacts within the 'Youth Entrepreneurship for Society' virtual exchange was to find out how the implementation of artefact-based telecollaborative tasks fosters 21st competences and social entrepreneurship in English for Specific Purposes settings. The project tasks were informed by constructionism and supported virtual collaboration an effort to promote social justice. They revolved around social entrepreneurship in English for Specific Purposes contexts, aiming to connect the classroom with the outside world through the involvement of local organisations, while fostering students' twenty-f…

050101 languages & linguisticsLinguistics and LanguageEntrepreneurshipCo-constructionTwenty-first century competences05 social sciences050301 educationConstructionismSocial SciencesEnglish for specific purposesLanguage and LinguisticsComputer Science ApplicationsVirtual exchangePedagogyConstructionismLlenguatge i llengües EnsenyamentEnglish for Specific Purposes0501 psychology and cognitive sciencesSociologyEducational SciencesArtefact construction0503 educationCritical CALL
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High pancreatic n-3 fatty acids prevent STZ-induced diabetes in fat-1 mice: inflammatory pathway inhibition.

2011

OBJECTIVE Because of confounding factors, the effects of dietary n-3 polyunsaturated fatty acids (PUFA) on type 1 diabetes remain to be clarified. We therefore evaluated whether fat-1 transgenic mice, a well-controlled experimental model endogenously synthesizing n-3 PUFA, were protected against streptozotocin (STZ)-induced diabetes. We then aimed to elucidate the in vivo response at the pancreatic level. RESEARCH DESIGN AND METHODS β-Cell destruction was produced by multiple low-doses STZ (MLD-STZ). Blood glucose level, plasma insulin level, and plasma lipid analysis were then performed. Pancreatic mRNA expression of cytokines, the monocyte chemoattractant protein, and GLUT2 were evaluate…

Blood GlucoseFatty Acid DesaturasesMalemedicine.medical_specialtyEndocrinology Diabetes and Metabolismmedicine.medical_treatmentBlotting WesternMice TransgenicBiologyProinflammatory cytokineDiabetes Mellitus Experimentalchemistry.chemical_compoundMiceInternal medicineFatty Acids Omega-3Internal MedicinemedicineAnimalsInsulinCaenorhabditis elegans ProteinsUnsaturated fatty acidLipoxinReverse Transcriptase Polymerase Chain ReactionInsulinTranscription Factor RelAStreptozotocinImmunohistochemistryLipidsNitric oxide synthasemedicine.anatomical_structureEndocrinologyMetabolismchemistryHyperglycemiabiology.proteinGLUT2FemalePancreasmedicine.drugSignal TransductionDiabetes
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Inhibition of the HER2 pathway by n-3 polyunsaturated fatty acids prevents breast cancer in fat-1 transgenic mice

2013

Overexpression of the tyrosine kinase receptor, ErbB2/HER2/Neu, occurs in 25–30% of invasive breast cancer (BC) with poor patient prognosis. Due to confounding factors, inconsistencies still remain regarding the protective effects of n-3 polyunsaturated fatty acids (PUFAs) on BC. We therefore evaluated whether fat-1 transgenic mice, endogenously synthesizing n-3 PUFAs from n-6 PUFAs, were protected against BC development, and we then aimed to study in vivo a mechanism potentially involved in such protection. E0771 BC cells were implanted into fat-1 and wild-type (WT) mice. After tumorigenesis examination, we analyzed the expression of proteins involved in the HER2 signaling pathway and lipi…

Genetically modified mouseFatty Acid DesaturasesDocosahexaenoic AcidsReceptor ErbB-3Receptor ErbB-2Breast NeoplasmsMice TransgenicQD415-436Biologymedicine.disease_causexenograft preventionBiochemistryReceptor tyrosine kinaseProto-Oncogene Proteins c-mycMiceEndocrinologyDownregulation and upregulationCell Line TumorFatty Acids Omega-3medicineAnimalsHumansCaenorhabditis elegans ProteinsResearch ArticlesCell Proliferationchemistry.chemical_classificationCell growthCell BiologyXenograft Model Antitumor AssaysGene Expression Regulation NeoplasticMice Inbred C57BLchemistryDocosahexaenoic acidImmunologyn-3 tissue enrichmentbiology.proteinCancer researchFemaleSignal transductionCarcinogenesispolyunsaturated fatty acid-derived mediatorsPolyunsaturated fatty acidSignal TransductionJournal of Lipid Research
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Online Intercultural Exchanges Through Digital Storytelling

2017

This article focuses on the affordances of a digital storytelling project in developing students' language, digital and other skills: learning and innovation, creativity, critical thinking, problem solving, team working, and life and career skills. The project was undertaken by university English for Specific Purposes students and was conducted within an Online Intercultural Exchange between the Cyprus University of Technology and the University of Valencia. Its design was based on a Project-Based Learning (PBL) methodology. It incorporated active learning and multimodal resources and capabilities. The need for transforming language teaching pedagogies was borne in mind, as it is necessary …

060201 languages & linguisticsLinguistics and LanguageDigital storytellingmedia_common.quotation_subject05 social sciences050301 education06 humanities and the artsEnglish for specific purposesCreativityTeam workingComputer Science ApplicationsEducationCritical thinking0602 languages and literatureActive learningComputingMilieux_COMPUTERSANDEDUCATIONMathematics educationLanguage educationComputer Vision and Pattern RecognitionPsychologyAffordance0503 educationmedia_commonInternational Journal of Computer-Assisted Language Learning and Teaching
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Virtual Exchange Project Reflective Essay

2021

Essay instructions: students are asked to write a personal reflective essay about the virtual exchange project (around 400 words), following the guidelines provided. Essay instructions: students are asked to write a personal reflective essay about the virtual exchange project (around 400 words), following the guidelines provided.

Software_GENERALComputingMilieux_THECOMPUTINGPROFESSIONUNESCO::LINGÜÍSTICA
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