0000000000175446
AUTHOR
A Venezia
Addition of either pioglitazone or a sulfonylurea in type 2 diabetic patients inadequately controlled with metformin alone: impact on cardiovascular events. A randomized controlled trial.
Abstract Background and aims Metformin is the first-line therapy in type 2 diabetes. In patients inadequately controlled with metformin, the addition of a sulfonylurea or pioglitazone are equally plausible options to improve glycemic control. However, these drugs have profound differences in their mechanism of action, side effects, and impact on cardiovascular risk factors. A formal comparison of these two therapies in terms of cardiovascular morbidity and mortality is lacking. The TOSCA.IT study was designed to explore the effects of adding pioglitazone or a sulfonylurea on cardiovascular events in type 2 diabetic patients inadequately controlled with metformin. Methods Multicentre, random…
A BRIEF DISSECTION'S GUIDE TO NORMAL MEDIASTINAL ANATOMY
The purpose of this article is to show the mediastinal dissection method used during the stage performed by a group of students from the Univrersity of palermo that, during the sumer of 2017, had the opportunity to spend a period of 4 weeks at the Department of Anatomy of The University of malta. The students were guided to practice dissection of some corpes to study various mediastinal organs. This experience permitted to the students to verify practically what they lernt in the books, and reperesented a unique opportunity for them to perform practice with cadavers, that is actually very difficult to do in italian universities.