0000000000181247

AUTHOR

John E. Lewis

showing 2 related works from this author

Telomere Length, SIRT1, and Insulin in Male Master Athletes: The Path to Healthy Longevity?

2021

AbstractLower SIRT1 and insulin resistance are associated with accelerated telomere shortening. This study investigated whether the lifestyle of master athletes can attenuate these age-related changes and thereby slow aging. We compared insulin, SIRT1, and telomere length in highly trained male master athletes (n=52; aged 49.9±7.2 yrs) and age-matched non-athletes (n=19; aged 47.3±8.9 yrs). This is a cross-sectional study, in which all data were collected in one visit. Overnight fasted SIRT1 and insulin levels in whole blood were assessed using commercial kits. Relative telomere length was determined in leukocytes through qPCR analyses. Master athletes had higher SIRT1, lower insulin, and l…

0301 basic medicineAdultMalemedicine.medical_specialtyAgingmedicine.medical_treatmentLongevityPhysical Therapy Sports Therapy and Rehabilitation030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineInsulin resistanceSirtuin 1Internal medicinemedicineLeukocytesHumansInsulinOrthopedics and Sports MedicineHealthy longevityWhole bloodbiologyAthletesbusiness.industryInsulinMiddle AgedTelomerebiology.organism_classificationmedicine.diseaseTelomere030104 developmental biologyEndocrinologyCross-Sectional StudiesAthletesbusinessInternational journal of sports medicine
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26th Annual Computational Neuroscience Meeting (CNS*2017): Part 2

2017

International audience; No abstract available

0301 basic medicineCerebellumComputer science[SDV]Life Sciences [q-bio]General Neurosciencelcsh:QP351-495Meeting Abstractslcsh:RC321-57103 medical and health sciencesCellular and Molecular Neurosciencelcsh:Neurophysiology and neuropsychology030104 developmental biologymedicine.anatomical_structuremedicineNeuronlcsh:Neurosciences. Biological psychiatry. NeuropsychiatryNeuroscienceComputingMilieux_MISCELLANEOUScomputational neuroscienceBMC Neuroscience
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