0000000000181306

AUTHOR

Svend Berger

showing 2 related works from this author

27Al NMR Study of the pH Dependent Hydrolysis Products of Al2(SO4)3 in Different Physiological Media

2018

Soluble inorganic aluminium compounds like aluminium sulfate or aluminium chloride have been challenged by the European Chemical Agency to induce germ cell mutagenicity. Before conducting mutagenicity tests, the hydrolysis products in water and in physiological solutions should be determined as a function of the concentration and pH. We used different 27Al NMR spectroscopic techniques (heteronuclear Overhauser effect spectroscopy (HOESY), exchange spectroscopy (EXSY), diffusion ordered (DOSY)) in this work to gain the information to study the aluminium species in solutions with Al2(SO4)3 concentrations of 50.0, 5.0, and 0.5 g/L and their pH and time dependent transformation. At low pH, thre…

0301 basic medicineAluminium chlorideInorganic chemistryPharmaceutical Sciencechemistry.chemical_elementNuclear Overhauser effectAluminium sulfate010402 general chemistry01 natural sciencesArticleAnalytical Chemistrylcsh:QD241-44103 medical and health scienceschemistry.chemical_compoundHydrolysislcsh:Organic chemistryAluminiumDrug DiscoverymedicinePhysical and Theoretical Chemistrychemistry.chemical_classificationOrganic ChemistryNMR0104 chemical sciences030104 developmental biologyhydrolysischemistryHeteronuclear moleculeChemistry (miscellaneous)REACHMolecular MedicineCounterionaluminium sulfate; hydrolysis; NMR; REACHaluminium sulfateTwo-dimensional nuclear magnetic resonance spectroscopymedicine.drugMolecules; Volume 23; Issue 4; Pages: 808
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Multilayer capsules: a promising microencapsulation system for transplantation of pancreatic islets

2001

In 1980, Lim and Sun introduced a microcapsule coated with an alginate/polylysine complex for encapsulation of pancreatic islets. Characteristic to this type of capsule is, that it consists of a plain membrane which is formed during a single procedural step. With such a simple process it is difficult to obtain instantly a membrane optimized with respect to all the properties requested for islet transplantation. To overcome these difficulties, it is recommended to build up the membrane in several consecutive steps, each optimized for a certain property. In this study, we have analysed such a multilayer microcapsule for the encapsulation of pancreatic islets. Therefore, empty and islet contai…

Transplantation HeterotopicMaterials scienceCompressive StrengthBiocompatibilityAlginatesDrug CompoundingAcrylic ResinsIslets of Langerhans TransplantationBiophysicsBiocompatible MaterialsBioengineeringPermeabilityRats Sprague-DawleyBiomaterialschemistry.chemical_compoundBiopolymersGlucuronic AcidMaterials TestingmedicineAnimalsPolyethyleneiminePolylysineParticle SizeMuscle SkeletalAcrylic resinCells CulturedHexuronic AcidsPancreatic isletsBiomaterialCapsuleProstheses and ImplantsFibrosisMicrospheresRatsQuaternary Ammonium CompoundsTransplantationmedicine.anatomical_structureMembranechemistryRats Inbred LewMechanics of MaterialsCarboxymethylcellulose Sodiumvisual_artPolylysineCeramics and Compositesvisual_art.visual_art_mediumFemalePolyethylenesBiomedical engineeringBiomaterials
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