0000000000182390

AUTHOR

Giampiero Maglia

0000-0001-9518-5877

showing 6 related works from this author

Chronic Apical and Nonapical Right Ventricular Pacing in Patients with High-Grade Atrioventricular Block: Results of the Right Pace Study

2018

Objective. The aim of the study was to compare the two approaches to chronic right ventricular pacing currently adopted in clinical practice: right ventricular apical (RVA) and non-RVA pacing. Background. Chronic RVA pacing is associated with an increased risk of atrial fibrillation, morbidity, and even mortality. Non-RVA pacing may yield more physiologic ventricular activation and provide potential long-term benefits and has recently been adopted as standard procedure at many implanting centers. Methods. The Right Pace study was a multicenter, prospective, single-blind, nonrandomized trial involving 437 patients indicated for dual-chamber pacemaker implantation with a high percentage of RV…

Genetics and Molecular Biology (all)Malemedicine.medical_specialtyArticle SubjectImmunology and Microbiology (all)Heart Ventricleslcsh:Medicine030204 cardiovascular system & hematologyBiochemistryGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicineInternal medicinemedicine80 and overHumansIn patientSingle-Blind Method030212 general & internal medicineInterventricular septumProspective StudiesAtrioventricular BlockAgedAged 80 and overGeneral Immunology and Microbiologybusiness.industrylcsh:RCardiac Pacing ArtificialReproducibility of ResultsAtrial fibrillationGeneral MedicineVentricular pacingmedicine.diseaseIncreased riskmedicine.anatomical_structureHigh grade atrioventricular blockTreatment OutcomeBaseline characteristicsHeart failureArtificialCardiologyClinical StudyQuality of LifeCardiac PacingFemalebusinessAged; Aged 80 and over; Female; Heart Ventricles; Humans; Male; Prospective Studies; Quality of Life; Reproducibility of Results; Single-Blind Method; Treatment Outcome; Atrioventricular Block; Cardiac Pacing Artificial; Biochemistry Genetics and Molecular Biology (all); Immunology and Microbiology (all)BioMed Research International
researchProduct

Right ventricular lead placement and ventricular dyssynchrony in a pacemaker population: An acute analysis from the evaluation of apical and non-apic…

2016

Malemedicine.medical_specialtyPacemaker ArtificialVentricular leadHeart VentriclesVentricular Dysfunction RightPopulation030204 cardiovascular system & hematologyHeart Ventricle03 medical and health sciences0302 clinical medicineInternal medicineMedicineHumansSingle-Blind Method030212 general & internal medicineProspective StudieseducationVentricular dyssynchronyAgedAged 80 and overeducation.field_of_studybusiness.industryCardiac Pacing ArtificialSeptumMiddle Agedmedicine.diseaseApex (geometry)Electrodes ImplantedPacemakerDyssynchronyProspective StudiePosition (obstetrics)Population SurveillanceCardiologyRight ventricleFemaleApexCardiology and Cardiovascular MedicinebusinessHumanInternational journal of cardiology
researchProduct

Magnitude of QRS duration reduction after biventricular pacing identifies responders to cardiac resynchronization therapy

2016

Background Several studies have investigated the association between native QRS duration (QRSd) or QRS narrowing and response to biventricular pacing. However, their results have been conflicting. The aim of our study was to determine the association between the relative change in QRS narrowing index (QI) and clinical outcome and prognosis in patients who undergo cardiac resynchronization therapy (CRT) implantation. Methods and results We included 311 patients in whom a CRT device was implanted in accordance with current guidelines for CRT. On implantation, the native QRS, the QRSd and the QI during CRT were measured. After 6 months, 220 (71%) patients showed a 10% reduction in LVESV. The m…

Malemedicine.medical_specialtymedicine.medical_treatmentCardiac resynchronization therapyHeart failure030204 cardiovascular system & hematologyFollow-Up StudieCohort Studies03 medical and health sciencesQRS complexReverse remodeling0302 clinical medicineHeart RateCardiovascular DiseaseInternal medicinemedicineHumansPacingIn patientProspective Studiescardiovascular diseases030212 general & internal medicineReverse remodelingAgedCardiac resynchronization therapyVentricular RemodelingECGbusiness.industryHazard ratioArea under the curveMiddle Agedmedicine.diseaseSurvival RateProspective StudieCardiovascular DiseasesHeart failurecardiovascular systemCardiologyFemaleCohort StudieCardiology and Cardiovascular MedicinebusinessFollow-Up StudiesHumanInternational Journal of Cardiology
researchProduct

Is there a right place to pace the right ventricle? Evaluation of apical and septal positions in a pacemaker population: Study protocol for a prospec…

2014

Abstract Introduction The main objective of research in pacemaker therapy has been to provide the best physiologic way to pace the heart. Despite the good results provided by right ventricular pacing minimization and by biventricular pacing in specific subsets of heart failure patients, these options present many limitations for standard pacemaker recipients. In these patients, pacing the right ventricle at alternative sites could result in a lower degree of left intraventricular dyssynchrony. Despite the lack of strong evidence and the difficulty in placing and accurately classifying the final lead position, pacing at alternative right ventricular sites seems to have become a standard proc…

MalePacemaker Artificialmedicine.medical_specialtyHeart Ventriclesmedicine.medical_treatmentPopulationCardiac resynchronization therapySTUDY DESIGNSeverity of Illness IndexInternal medicinePACEMAKERmedicineHumansSingle-Blind MethodPharmacology (medical)Prospective StudieseducationVentricular dyssynchronyHeart Failureeducation.field_of_studyEjection fractionDYSSYNCHRONYbusiness.industryGeneral Medicinemedicine.diseaseImplantable cardioverter-defibrillatorHospitalizationmedicine.anatomical_structureEchocardiographyResearch DesignVentriclePACEMAKER; STUDY DESIGN; DYSSYNCHRONYHeart failureQuality of LifeCardiologyEnd-diastolic volumeFemalebusinessContemporary Clinical Trials
researchProduct

Update on Brugada Syndrome 2019

2021

Brugada syndrome (BrS) was first described in 1992 as an aberrant pattern of ST segment elevation in right precordial leads with a high incidence of sudden cardiac death (SCD) in patients with structurally normal heart. It represents 4% ∼ 12% of all SCD and 20% of SCD in patients with structurally normal heart. The extremely wide genetic heterogeneity of BrS and other inherited cardiac disorders makes this new area of genetic arrhytmology a fascinating one. This review shows the state of art in diagnosis, management, and treatment of BrS focusing all the aspects regarding genetics and Preimplant Genetic Diagnosis (PGD) of embryos, overlapping syndromes, risk stratification, familial screeni…

medicine.medical_specialtymedicine.medical_treatment030204 cardiovascular system & hematologyRisk Assessmentsudden cardiac deathSudden cardiac deathElectrocardiography03 medical and health sciences0302 clinical medicineInternal medicinemedicineHumansST segmentBrugada syndromeIn patient030212 general & internal medicineCardiac disordersBrugada syndromeMedicine(all)business.industryGenetic heterogeneityGeneral Medicinemedicine.diseaseImplantable cardioverter-defibrillatorBrugada Syndrome.Defibrillators ImplantableCardiologyhigh incidenceCardiology and Cardiovascular MedicinebusinessRisk assessmentCurrent Problems in Cardiology
researchProduct

Role of Rate Control and Regularization Through Pacing in Patients With Chronic Atrial Fibrillation and Preserved Ventricular Function: The VRR Study

2006

Aim: High heart rates in chronic atrial fibrillation (CAF) is one of the factors responsible for hemodynamic alterations and may lead to tachycardiomyopathies. The ventricular rate regulation (VRR) study evaluates the effect of ventricular rate regularization in CAF patients with preserved ventricular function, marked ventricular rate variability, and indications for pacemaker (PM) implantation owing to symptomatic pauses. Rate regularization was achieved using VRR algorithm (INSIGNIA® pacemakers, Guidant Corp., St. Paul, MN, USA). Methods: One month after PM implantation, 58 patients followed two 3-month crossover periods (VRR-OFF; VRR-ON) in which the VRR algorithm was randomized and comp…

Malemedicine.medical_specialtyHemodynamicsVentricular Dysfunction LeftHeart RateInternal medicineAtrial FibrillationmedicineHumansChronic atrial fibrillationIn patientLead (electronics)Ventricular functionbusiness.industryCardiac Pacing ArtificialRate controlAtrial fibrillationGeneral MedicineMiddle Agedmedicine.diseaseTreatment OutcomeWalk testAnesthesiaChronic DiseaseTachycardia VentricularCardiologyFemaleCardiology and Cardiovascular MedicinebusinessPacing and Clinical Electrophysiology
researchProduct