0000000000183132

AUTHOR

Li W.

Maximin Model Robust Discrete Choice Experiments

Discrete choice experiments have their genesis in conjoint analysis, which was based on first-order models. For this and other reasons, discrete choice experiments in practice are usually designed for estimation of main effects. In this paper, we explore the construction of maximin model robust designs when the experimenter is concerned about the presence of interactions. We consider three classes of models—main effects models, main effects models plus first-order interactions, and secondorder models, and we construct designs that maximize the minimum efficiency of the design for the three competing models. We do so first with standard linear models and then extend our analysis to nonlinear…

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Death in hospital following ICU discharge: insights from the LUNG SAFE study

Abstract Background To determine the frequency of, and factors associated with, death in hospital following ICU discharge to the ward. Methods The Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE study was an international, multicenter, prospective cohort study of patients with severe respiratory failure, conducted across 459 ICUs from 50 countries globally. This study aimed to understand the frequency and factors associated with death in hospital in patients who survived their ICU stay. We examined outcomes in the subpopulation discharged with no limitations of life sustaining treatments (‘treatment limitations’), and the subpopulations with tre…

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