SIMPLE, BIOCOMPATIBLE AND COST-EFFECTIVE INULIN BASED siRNA DELIVERY SYSTEMS

SIMPLE, BIOCOMPATIBLE AND COST-EFFECTIVE INULIN BASED siRNA DELIVERY SYSTEMS

Solubilizzazione di composti organici in micelle di copolimeri termo- e pH-sensibili

Inulin-Spermine derivatives for siRNA delivery

POLYMERIC FLUORESCENT NANOPARTICLES BASED ON A POLYASPARTAMIDE FOR IMAGING APPLICATIONS: EVALUATION OF GALACTOSE TARGETING ON HEPG2 CELL INTERNALIZATION

INULIN GRAFT CO-POLYMERS AS SELF-ASSEMBLING MICELLES FOR DRUG DELIVERY

Farmacologia Generale

Entrapment of an EGFR inhibitor into nanostructured lipid carriers (NLC) improves its antitumor activity against human hepatocarcinoma cells

Background: In hepatocellular carcinoma (HCC), different signaling pathways are de-regulated, and among them, the expression of the epidermal growth factor receptor (EGFR). Tyrphostin AG-1478 is a lipophilic low molecular weight inhibitor of EGFR, preferentially acting on liver tumor cells. In order to overcome its poor drug solubility and thus improving its anticancer activity, it was entrapped into nanostructured lipid carriers (NLC) by using safe ingredients for parenteral delivery. Results: Nanostructured lipid carriers (NLC) carrying tyrphostin AG-1478 were prepared by using the nanoprecipitation method and different matrix compositions. The best system in terms of mean size, PDI, zeta…

Inulin Coated Gold Nanoparticles As a Potential Tool For Cancer Therapy

Solubilization of oils in aqueous solution of star-like block copolymer with thermo- and pH-sensitive features

FUNCTIONALITATION OF HYDROPHOBIC SURFACES WITH A POLYASPARTAMIDE-BASED DERIVATIVE FOR BIOMEDICAL APPLICATION