0000000000184416

AUTHOR

R. Rosenberg

showing 2 related works from this author

Oral and Poster Papers Submitted for Presentation at the 5th Congress of the EUGMS “Geriatric Medicine in a Time of Generational Shift September 3–6,…

2008

GerontologyGeriatrics0303 health sciencesmedicine.medical_specialtyNutrition and Dietetics030309 nutrition & dieteticsGeriatrics gerontologybusiness.industrymedia_common.quotation_subjectAlternative medicineMedicine (miscellaneous)03 medical and health sciencesPresentation0302 clinical medicinemedicine030212 general & internal medicineGeriatrics and GerontologybusinessQuality of Life Researchmedia_commonThe Journal of Nutrition Health and Aging
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Drug treatment of panic disorder: early response to treatment as a predictor of final outcome

1990

One of the core problems in clinical research is the detection of early changes in target symptoms that predict future therapeutic outcome. To analyze potential predictors of outcome, data of a multicenter study on patients with panic disorder were used. A total of 1010 patients were randomly allocated either to alprazolam, imipramine or placebo treatment. Early improvement in the number of spontaneous panic attacks within the first week of treatment predicted outcome exclusively in the alprazolam group. In contrast, placebo responders and nonresponders were differentiated by early changes in anticipatory anxiety intensity. For tricyclic antidepressants such as imipramine an evaluation peri…

AdultMaleImipraminemedicine.medical_specialtyPlaceboImipramineDouble-Blind MethodInternal medicinemedicineHumansPsychiatryAgoraphobiaPsychiatric Status Rating Scaleschemistry.chemical_classificationAlprazolamPanic disorderPanicmedicine.diseaseAnxiety DisordersPanicPsychiatry and Mental healthClinical researchchemistryAlprazolamAnxietyFemalemedicine.symptomArousalPsychologyTricyclicmedicine.drugActa Psychiatrica Scandinavica
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